These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 9634000)

  • 1. Increased concentrations of methylated 6-mercaptopurine metabolites and 6-thioguanine nucleotides in human leukemic cells in vitro by methotrexate.
    Giverhaug T; Loennechen T; Aarbakke J
    Biochem Pharmacol; 1998 May; 55(10):1641-6. PubMed ID: 9634000
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo.
    Giverhaug T; Fuskevaag OM; Aarbakke J
    Cancer Chemother Pharmacol; 1997; 40(4):367-70. PubMed ID: 9225958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase.
    Krynetski EY; Krynetskaia NF; Yanishevski Y; Evans WE
    Mol Pharmacol; 1995 Jun; 47(6):1141-7. PubMed ID: 7603453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.
    Dervieux T; Blanco JG; Krynetski EY; Vanin EF; Roussel MF; Relling MV
    Cancer Res; 2001 Aug; 61(15):5810-6. PubMed ID: 11479220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro.
    Liliemark J; Pettersson B; Peterson C
    Leuk Res; 1992; 16(3):275-80. PubMed ID: 1373210
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment.
    Zaza G; Cheok M; Yang W; Panetta JC; Pui CH; Relling MV; Evans WE
    Blood; 2005 Sep; 106(5):1778-85. PubMed ID: 15905191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Establishment of thiopurine S-methyltransferase gene knockdown in jurkat T-lymphocytes: an in vitro model of TPMT polymorphism.
    Misdaq M; Andag R; Oellerich M; Asif AR; von Ahsen N
    Ther Drug Monit; 2012 Oct; 34(5):584-92. PubMed ID: 22972540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine.
    Estlin EJ
    Cancer Treat Rev; 2001 Dec; 27(6):351-63. PubMed ID: 11908928
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Utility of measuring 6-methylmercaptopurine and 6-thioguanine nucleotide levels in managing inflammatory bowel disease patients treated with 6-mercaptopurine in a clinical practice setting.
    Mardini HE; Arnold GL
    J Clin Gastroenterol; 2003; 36(5):390-5. PubMed ID: 12702978
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Maintenance therapy for acute lymphoblastic leukemia: basic science and clinical translations.
    Toksvang LN; Lee SHR; Yang JJ; Schmiegelow K
    Leukemia; 2022 Jul; 36(7):1749-1758. PubMed ID: 35654820
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intensification of mercaptopurine/methotrexate maintenance chemotherapy may increase the risk of relapse for some children with acute lymphoblastic leukemia.
    Schmiegelow K; Björk O; Glomstein A; Gustafsson G; Keiding N; Kristinsson J; Mäkipernaa A; Rosthøj S; Szumlanski C; Sørensen TM; Weinshilboum R
    J Clin Oncol; 2003 Apr; 21(7):1332-9. PubMed ID: 12663723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G; Westerhof GR; Kathmann I; Rademaker BC; Rijksen G; Schornagel JH
    Cancer Res; 1989 May; 49(9):2455-9. PubMed ID: 2706633
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells.
    Karim H; Ghalali A; Lafolie P; Vitols S; Fotoohi AK
    Biochem Biophys Res Commun; 2013 Jul; 437(2):280-6. PubMed ID: 23811272
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia.
    Lennard L; Lilleyman JS; Van Loon J; Weinshilboum RM
    Lancet; 1990 Jul; 336(8709):225-9. PubMed ID: 1973780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.
    Coulthard SA; Hogarth LA; Little M; Matheson EC; Redfern CP; Minto L; Hall AG
    Mol Pharmacol; 2002 Jul; 62(1):102-9. PubMed ID: 12065760
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial.
    Nielsen SN; Grell K; Nersting J; Abrahamsson J; Lund B; Kanerva J; Jónsson ÓG; Vaitkeviciene G; Pruunsild K; Hjalgrim LL; Schmiegelow K
    Lancet Oncol; 2017 Apr; 18(4):515-524. PubMed ID: 28258828
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.
    Dervieux T; Hancock M; Evans W; Pui CH; Relling MV
    Leukemia; 2002 Feb; 16(2):209-12. PubMed ID: 11840287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells.
    Adamson PC; Balis FM; Hawkins ME; Murphy RF; Poplack DG
    Biochem Pharmacol; 1993 Nov; 46(9):1627-36. PubMed ID: 8240420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.
    Wong DR; Pierik M; Seinen ML; van Bodegraven AA; Gilissen LP; Bus P; Bakker JA; Masclee AA; Neef C; Engels LG; Hooymans PM
    J Crohns Colitis; 2014 Feb; 8(2):120-8. PubMed ID: 23932783
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia.
    Adamson PC; Poplack DG; Balis FM
    Leuk Res; 1994 Nov; 18(11):805-10. PubMed ID: 7967706
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.