These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 9634007)

  • 21. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
    Dolan ME; Pegg AE; Dumenco LL; Moschel RC; Gerson SL
    Carcinogenesis; 1991 Dec; 12(12):2305-9. PubMed ID: 1747932
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Beta-glucuronidase-cleavable prodrugs of O6-benzylguanine and O6-benzyl-2'-deoxyguanosine.
    Wei G; Loktionova NA; Pegg AE; Moschel RC
    J Med Chem; 2005 Jan; 48(1):256-61. PubMed ID: 15634019
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Reaction of O6-benzylguanine-resistant mutants of human O6-alkylguanine-DNA alkyltransferase with O6-benzylguanine in oligodeoxyribonucleotides.
    Pegg AE; Kanugula S; Edara S; Pauly GT; Moschel RC; Goodtzova K
    J Biol Chem; 1998 May; 273(18):10863-7. PubMed ID: 9556560
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inactivation of human O(6)-alkylguanine-DNA alkyltransferase by modified oligodeoxyribonucleotides containing O(6)-benzylguanine.
    Pegg AE; Goodtzova K; Loktionova NA; Kanugula S; Pauly GT; Moschel RC
    J Pharmacol Exp Ther; 2001 Mar; 296(3):958-65. PubMed ID: 11181929
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inactivation of O6-alkylguanine-DNA alkyltransferase. 1. Novel O6-(hetarylmethyl)guanines having basic rings in the side chain.
    McElhinney RS; Donnelly DJ; McCormick JE; Kelly J; Watson AJ; Rafferty JA; Elder RH; Middleton MR; Willington MA; McMurry TB; Margison GP
    J Med Chem; 1998 Dec; 41(26):5265-71. PubMed ID: 9857094
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine.
    Shankar S; Zalutsky MR; Friedman H; Vaidyanathan G
    Nucl Med Biol; 2006 Apr; 33(3):399-407. PubMed ID: 16631089
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design of a hypoxia-activated prodrug inhibitor of O6-alkylguanine-DNA alkyltransferase.
    Zhu R; Seow HA; Baumann RP; Ishiguro K; Penketh PG; Shyam K; Sartorelli AC
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6242-7. PubMed ID: 22932317
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
    Hansen RJ; Nagasubramanian R; Delaney SM; Cherian MM; Lin S; Kogan SC; Dolan ME
    J Pharmacol Exp Ther; 2005 Dec; 315(3):1247-55. PubMed ID: 16126841
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide.
    Kokkinakis DM; Bocangel DB; Schold SC; Moschel RC; Pegg AE
    Clin Cancer Res; 2001 Feb; 7(2):421-8. PubMed ID: 11234899
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Metabolism of O6-benzylguanine, an inactivator of O6-alkylguanine-DNA alkyltransferase.
    Dolan ME; Chae MY; Pegg AE; Mullen JH; Friedman HS; Moschel RC
    Cancer Res; 1994 Oct; 54(19):5123-30. PubMed ID: 7923129
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.
    Crone TM; Pegg AE
    Cancer Res; 1993 Oct; 53(20):4750-3. PubMed ID: 8402653
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine.
    Kanugula S; Goodtzova K; Edara S; Pegg AE
    Biochemistry; 1995 May; 34(21):7113-9. PubMed ID: 7766621
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM; Moschel RC; Chae MY; McLaughlin PJ; Zagon IS; Pegg AE
    Cancer Res; 1995 Sep; 55(18):4085-91. PubMed ID: 7664284
    [TBL] [Abstract][Full Text] [Related]  

  • 34. [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine].
    Wan Y; Wu D; Gao H
    Zhonghua Zhong Liu Za Zhi; 2000 Jul; 22(4):290-3. PubMed ID: 11778552
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Phase I clinical and pharmacological study of O6-benzylguanine followed by carmustine in patients with advanced cancer.
    Schilsky RL; Dolan ME; Bertucci D; Ewesuedo RB; Vogelzang NJ; Mani S; Wilson LR; Ratain MJ
    Clin Cancer Res; 2000 Aug; 6(8):3025-31. PubMed ID: 10955780
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Resistance of the human O6-alkylguanine-DNA alkyltransferase containing arginine at codon 160 to inactivation by O6-benzylguanine.
    Edara S; Kanugula S; Goodtzova K; Pegg AE
    Cancer Res; 1996 Dec; 56(24):5571-5. PubMed ID: 8971155
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model.
    Liu L; Lee K; Wasan E; Gerson SL
    Cancer Res; 1996 Apr; 56(8):1880-5. PubMed ID: 8620508
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine.
    Zhu R; Liu MC; Luo MZ; Penketh PG; Baumann RP; Shyam K; Sartorelli AC
    J Med Chem; 2011 Nov; 54(21):7720-8. PubMed ID: 21955333
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Heterogeneity of O6-alkylguanine-DNA-alkyltransferase measured by flow cytometric analysis in blood and bone marrow mononuclear cells.
    Liu L; Lee K; Schupp J; Koç ON; Gerson SL
    Clin Cancer Res; 1998 Feb; 4(2):475-81. PubMed ID: 9516939
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Leukocyte O6-alkylguanine-DNA alkyltransferase from human donors is uniformly sensitive to O6-benzylguanine.
    Gerson SL; Schupp J; Liu L; Pegg AE; Srinivasen S
    Clin Cancer Res; 1999 Mar; 5(3):521-4. PubMed ID: 10100702
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.