BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 9642078)

  • 1. Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands.
    Rahuel J; García-Echeverría C; Furet P; Strauss A; Caravatti G; Fretz H; Schoepfer J; Gay B
    J Mol Biol; 1998 Jun; 279(4):1013-22. PubMed ID: 9642078
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.
    Nioche P; Liu WQ; Broutin I; Charbonnier F; Latreille MT; Vidal M; Roques B; Garbay C; Ducruix A
    J Mol Biol; 2002 Feb; 315(5):1167-77. PubMed ID: 11827484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain.
    Furet P; Gay B; García-Echeverría C; Rahuel J; Fretz H; Schoepfer J; Caravatti G
    J Med Chem; 1997 Oct; 40(22):3551-6. PubMed ID: 9357522
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
    Ogura K; Tsuchiya S; Terasawa H; Yuzawa S; Hatanaka H; Mandiyan V; Schlessinger J; Inagaki F
    J Mol Biol; 1999 Jun; 289(3):439-45. PubMed ID: 10356320
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.
    Eck MJ; Shoelson SE; Harrison SC
    Nature; 1993 Mar; 362(6415):87-91. PubMed ID: 7680435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain.
    Furet P; Gay B; Caravatti G; García-Echeverría C; Rahuel J; Schoepfer J; Fretz H
    J Med Chem; 1998 Aug; 41(18):3442-9. PubMed ID: 9719597
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.
    Gay B; Furet P; García-Echeverría C; Rahuel J; Chène P; Fretz H; Schoepfer J; Caravatti G
    Biochemistry; 1997 May; 36(19):5712-8. PubMed ID: 9153411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermodynamic and structural analysis of phosphotyrosine polypeptide binding to Grb2-SH2.
    McNemar C; Snow ME; Windsor WT; Prongay A; Mui P; Zhang R; Durkin J; Le HV; Weber PC
    Biochemistry; 1997 Aug; 36(33):10006-14. PubMed ID: 9254595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
    Oishi S; Karki RG; Kang SU; Wang X; Worthy KM; Bindu LK; Nicklaus MC; Fisher RJ; Burke TR
    J Med Chem; 2005 Feb; 48(3):764-72. PubMed ID: 15689160
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase.
    Siegal G; Davis B; Kristensen SM; Sankar A; Linacre J; Stein RC; Panayotou G; Waterfield MD; Driscoll PC
    J Mol Biol; 1998 Feb; 276(2):461-78. PubMed ID: 9512716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.
    Liu WQ; Vidal M; Olszowy C; Million E; Lenoir C; Dhôtel H; Garbay C
    J Med Chem; 2004 Feb; 47(5):1223-33. PubMed ID: 14971902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Solution structure and dynamics of G1TE, a nonphosphorylated cyclic peptide inhibitor for the Grb2 SH2 domain.
    Lou YC; Lung FD; Pai MT; Tzeng SR; Wei SY; Roller PP; Cheng JW
    Arch Biochem Biophys; 1999 Dec; 372(2):309-14. PubMed ID: 10600169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
    Ettmayer P; France D; Gounarides J; Jarosinski M; Martin MS; Rondeau JM; Sabio M; Topiol S; Weidmann B; Zurini M; Bair KW
    J Med Chem; 1999 Mar; 42(6):971-80. PubMed ID: 10090780
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.
    Wei CQ; Gao Y; Lee K; Guo R; Li B; Zhang M; Yang D; Burke TR
    J Med Chem; 2003 Jan; 46(2):244-54. PubMed ID: 12519063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands.
    Yao ZJ; King CR; Cao T; Kelley J; Milne GW; Voigt JH; Burke TR
    J Med Chem; 1999 Jan; 42(1):25-35. PubMed ID: 9888830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differentiation of peptide molecular recognition by phospholipase C gamma-1 Src homology-2 domain and a mutant Tyr phosphatase PTP1bC215S.
    MacLean D; Sefler AM; Zhu G; Decker SJ; Saltiel AR; Singh J; McNamara D; Dobrusin EM; Sawyer TK
    Protein Sci; 1995 Jan; 4(1):13-20. PubMed ID: 7773170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin.
    Shi YH; Song YL; Lin DH; Tan J; Roller PP; Li Q; Long YQ; Song GQ
    Biochem Biophys Res Commun; 2005 May; 330(4):1254-61. PubMed ID: 15823578
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory effects of rosmarinic acid on Lck SH2 domain binding to a synthetic phosphopeptide.
    Ahn SC; Oh WK; Kim BY; Kang DO; Kim MS; Heo GY; Ahn JS
    Planta Med; 2003 Jul; 69(7):642-6. PubMed ID: 12898421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Grb2 SH2 domain-binding peptide analogs as potential anticancer agents.
    Lung FD; Tsai JY
    Biopolymers; 2003; 71(2):132-40. PubMed ID: 12767115
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution.
    Tong L; Warren TC; King J; Betageri R; Rose J; Jakes S
    J Mol Biol; 1996 Mar; 256(3):601-10. PubMed ID: 8604142
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.