191 related articles for article (PubMed ID: 9647670)
21. Selective protection and relative importance of the carboxylic acid groups of zaragozic acid A for squalene synthase inhibition.
Biftu T; Acton JJ; Berger GD; Bergstrom JD; Dufresne C; Kurtz MM; Marquis RW; Parsons WH; Rew DR; Wilson KE
J Med Chem; 1994 Feb; 37(3):421-4. PubMed ID: 8308869
[TBL] [Abstract][Full Text] [Related]
22. [Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].
Corsini A; Arnaboldi L; Quarato P; Ferri N; Granata A; Fumagalli R; Paoletti R
C R Seances Soc Biol Fil; 1997; 191(2):169-94. PubMed ID: 9255346
[TBL] [Abstract][Full Text] [Related]
23. Inhibition of squalene synthase of rat liver by novel 3' substituted quinuclidines.
McTaggart F; Brown GR; Davidson RG; Freeman S; Holdgate GA; Mallion KB; Mirrlees DJ; Smith GJ; Ward WH
Biochem Pharmacol; 1996 Jun; 51(11):1477-87. PubMed ID: 8630089
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
Flint OP; Masters BA; Gregg RE; Durham SK
Toxicol Appl Pharmacol; 1997 Jul; 145(1):91-8. PubMed ID: 9221828
[TBL] [Abstract][Full Text] [Related]
25. Farnesol biosynthesis in Candida albicans: cellular response to sterol inhibition by zaragozic acid B.
Hornby JM; Kebaara BW; Nickerson KW
Antimicrob Agents Chemother; 2003 Jul; 47(7):2366-9. PubMed ID: 12821501
[TBL] [Abstract][Full Text] [Related]
26. The preparation of zaragozic acid A analogues by directed biosynthesis.
Chen TS; Petuch B; MacConnell J; White R; Dezeny G; Arison B; Bergstrom JD; Colwell L; Huang L; Monaghan RL
J Antibiot (Tokyo); 1994 Nov; 47(11):1290-4. PubMed ID: 8002393
[TBL] [Abstract][Full Text] [Related]
27. Total synthesis of the squalene synthase inhibitor zaragozic acid C.
Nakamura S
Chem Pharm Bull (Tokyo); 2005 Jan; 53(1):1-10. PubMed ID: 15635219
[TBL] [Abstract][Full Text] [Related]
28. The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors.
Chan C; Andreotti D; Cox B; Dymock BW; Hutson JL; Keeling SE; McCarthy AD; Procopiou PA; Ross BC; Sareen M; Scicinski JJ; Sharratt PJ; Snowden MA; Watson NS
J Med Chem; 1996 Jan; 39(1):207-16. PubMed ID: 8568810
[TBL] [Abstract][Full Text] [Related]
29. Inhibitors of cholesterol biosynthesis increase hepatic low-density lipoprotein receptor protein degradation.
Ness GC; Zhao Z; Lopez D
Arch Biochem Biophys; 1996 Jan; 325(2):242-8. PubMed ID: 8561503
[TBL] [Abstract][Full Text] [Related]
30. The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues.
Procopiou PA; Cox B; Kirk BE; Lester MG; McCarthy AD; Sareen M; Sharratt PJ; Snowden MA; Spooner SJ; Watson NS; Widdowson J
J Med Chem; 1996 Mar; 39(7):1413-22. PubMed ID: 8691471
[TBL] [Abstract][Full Text] [Related]
31. Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor.
Vukelic S; Stojadinovic O; Pastar I; Vouthounis C; Krzyzanowska A; Das S; Samuels HH; Tomic-Canic M
J Biol Chem; 2010 Jan; 285(3):1980-8. PubMed ID: 19903814
[TBL] [Abstract][Full Text] [Related]
32. Protein farnesyltransferase: measurement of enzymatic activity in 96-well format using TopCount microplate scintillation counting technology.
Harwood HJ
Anal Biochem; 1995 Apr; 226(2):268-78. PubMed ID: 7793628
[TBL] [Abstract][Full Text] [Related]
33. Inhibition of squalene synthase upregulates PCSK9 expression in rat liver.
Bedi M; Niesen M; Lopez D
Arch Biochem Biophys; 2008 Feb; 470(2):116-9. PubMed ID: 18054775
[TBL] [Abstract][Full Text] [Related]
34. A symmetry-based formal synthesis of zaragozic acid A.
Freeman-Cook KD; Halcomb RL
J Org Chem; 2000 Sep; 65(19):6153-9. PubMed ID: 10987953
[TBL] [Abstract][Full Text] [Related]
35. Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives.
Ponpipom MM; Girotra NN; Bugianesi RL; Roberts CD; Berger GD; Burk RM; Marquis RW; Parsons WH; Bartizal KF; Bergstom JD
J Med Chem; 1994 Nov; 37(23):4031-51. PubMed ID: 7966163
[TBL] [Abstract][Full Text] [Related]
36. Selective inhibition of cholesterol biosynthesis in brain cells by squalestatin 1.
Crick DC; Suders J; Kluthe CM; Andres DA; Waechter CJ
J Neurochem; 1995 Sep; 65(3):1365-73. PubMed ID: 7643114
[TBL] [Abstract][Full Text] [Related]
37. Aspergillus flavus squalene synthase as an antifungal target: Expression, activity, and inhibition.
Song J; Shang N; Baig N; Yao J; Shin C; Kim BK; Li Q; Malwal SR; Oldfield E; Feng X; Guo RT
Biochem Biophys Res Commun; 2019 May; 512(3):517-523. PubMed ID: 30904161
[TBL] [Abstract][Full Text] [Related]
38. Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes.
Pant A; Kocarek TA
Drug Metab Dispos; 2016 Mar; 44(3):352-5. PubMed ID: 26700959
[TBL] [Abstract][Full Text] [Related]
39. The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. II. Structure elucidation.
Sidebottom PJ; Highcock RM; Lane SJ; Procopiou PA; Watson NS
J Antibiot (Tokyo); 1992 May; 45(5):648-58. PubMed ID: 1624367
[TBL] [Abstract][Full Text] [Related]
40. Antimicrobial activity of viridiofungins.
Onishi JC; Milligan JA; Basilio A; Bergstrom J; Curotto J; Huang L; Meinz M; Nallin-Omstead M; Pelaez F; Rew D; Salvatore M; Thompson J; Vicente F; Kurtz MB
J Antibiot (Tokyo); 1997 Apr; 50(4):334-8. PubMed ID: 9186560
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
