BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 9651162)

  • 1. Synthesis and evaluation of peptidyl Michael acceptors that inactivate human rhinovirus 3C protease and inhibit virus replication.
    Kong JS; Venkatraman S; Furness K; Nimkar S; Shepherd TA; Wang QM; Aubé J; Hanzlik RP
    J Med Chem; 1998 Jul; 41(14):2579-87. PubMed ID: 9651162
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements.
    Webber SE; Okano K; Little TL; Reich SH; Xin Y; Fuhrman SA; Matthews DA; Love RA; Hendrickson TF; Patick AK; Meador JW; Ferre RA; Brown EL; Ford CE; Binford SL; Worland ST
    J Med Chem; 1998 Jul; 41(15):2786-805. PubMed ID: 9667969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements.
    Dragovich PS; Prins TJ; Zhou R; Webber SE; Marakovits JT; Fuhrman SA; Patick AK; Matthews DA; Lee CA; Ford CE; Burke BJ; Rejto PA; Hendrickson TF; Tuntland T; Brown EL; Meador JW; Ferre RA; Harr JE; Kosa MB; Worland ST
    J Med Chem; 1999 Apr; 42(7):1213-24. PubMed ID: 10197965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.
    Dragovich PS; Webber SE; Babine RE; Fuhrman SA; Patick AK; Matthews DA; Lee CA; Reich SH; Prins TJ; Marakovits JT; Littlefield ES; Zhou R; Tikhe J; Ford CE; Wallace MB; Meador JW; Ferre RA; Brown EL; Binford SL; Harr JE; DeLisle DM; Worland ST
    J Med Chem; 1998 Jul; 41(15):2806-18. PubMed ID: 9667970
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics.
    Dragovich PS; Prins TJ; Zhou R; Fuhrman SA; Patick AK; Matthews DA; Ford CE; Meador JW; Ferre RA; Worland ST
    J Med Chem; 1999 Apr; 42(7):1203-12. PubMed ID: 10197964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies.
    Dragovich PS; Webber SE; Babine RE; Fuhrman SA; Patick AK; Matthews DA; Reich SH; Marakovits JT; Prins TJ; Zhou R; Tikhe J; Littlefield ES; Bleckman TM; Wallace MB; Little TL; Ford CE; Meador JW; Ferre RA; Brown EL; Binford SL; DeLisle DM; Worland ST
    J Med Chem; 1998 Jul; 41(15):2819-34. PubMed ID: 9667971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides.
    Kati WM; Sham HL; McCall JO; Montgomery DA; Wang GT; Rosenbrook W; Miesbauer L; Buko A; Norbeck DW
    Arch Biochem Biophys; 1999 Feb; 362(2):363-75. PubMed ID: 9989947
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human rhinovirus 3C protease as a potential target for the development of antiviral agents.
    Wanga QM; Chen SH
    Curr Protein Pept Sci; 2007 Feb; 8(1):19-27. PubMed ID: 17305557
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics.
    Dragovich PS; Prins TJ; Zhou R; Johnson TO; Hua Y; Luu HT; Sakata SK; Brown EL; Maldonado FC; Tuntland T; Lee CA; Fuhrman SA; Zalman LS; Patick AK; Matthews DA; Wu EY; Guo M; Borer BC; Nayyar NK; Moran T; Chen L; Rejto PA; Rose PW; Guzman MC; Dovalsantos EZ; Lee S; McGee K; Mohajeri M; Liese A; Tao J; Kosa MB; Liu B; Batugo MR; Gleeson JP; Wu ZP; Liu J; Meador JW; Ferre RA
    J Med Chem; 2003 Oct; 46(21):4572-85. PubMed ID: 14521419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New anti-viral drugs for the treatment of the common cold.
    Maugeri C; Alisi MA; Apicella C; Cellai L; Dragone P; Fioravanzo E; Florio S; Furlotti G; Mangano G; Ombrato R; Luisi R; Pompei R; Rincicotti V; Russo V; Vitiello M; Cazzolla N
    Bioorg Med Chem; 2008 Mar; 16(6):3091-107. PubMed ID: 18248816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-covalent inhibitors of rhinovirus 3C protease.
    Baxter A; Chambers M; Edfeldt F; Edman K; Freeman A; Johansson C; King S; Morley A; Petersen J; Rawlins P; Spadola L; Thong B; Van de Poël H; Williams N
    Bioorg Med Chem Lett; 2011 Jan; 21(2):777-80. PubMed ID: 21183345
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A continuous colorimetric assay for rhinovirus-14 3C protease using peptide p-nitroanilides as substrates.
    Wang QM; Johnson RB; Cox GA; Villarreal EC; Loncharich RJ
    Anal Biochem; 1997 Oct; 252(2):238-45. PubMed ID: 9344409
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease.
    Patick AK; Brothers MA; Maldonado F; Binford S; Maldonado O; Fuhrman S; Petersen A; Smith GJ; Zalman LS; Burns-Naas LA; Tran JQ
    Antimicrob Agents Chemother; 2005 Jun; 49(6):2267-75. PubMed ID: 15917520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and structure-activity relationships of novel inhibitors of human rhinovirus 3C protease.
    Kawatkar SP; Gagnon M; Hoesch V; Tiong-Yip C; Johnson K; Ek M; Nilsson E; Lister T; Olsson L; Patel J; Yu Q
    Bioorg Med Chem Lett; 2016 Jul; 26(14):3248-3252. PubMed ID: 27265257
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors.
    Im I; Lee ES; Choi SJ; Lee JY; Kim YC
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3632-6. PubMed ID: 19464175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors.
    Namoto K; Sirockin F; Sellner H; Wiesmann C; Villard F; Moreau RJ; Valeur E; Paulding SC; Schleeger S; Schipp K; Loup J; Andrews L; Swale R; Robinson M; Farady CJ
    Bioorg Med Chem Lett; 2018 Mar; 28(5):906-909. PubMed ID: 29433930
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes.
    Matthews DA; Dragovich PS; Webber SE; Fuhrman SA; Patick AK; Zalman LS; Hendrickson TF; Love RA; Prins TJ; Marakovits JT; Zhou R; Tikhe J; Ford CE; Meador JW; Ferre RA; Brown EL; Binford SL; Brothers MA; DeLisle DM; Worland ST
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11000-7. PubMed ID: 10500114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression and purification of recombinant rhinovirus 14 3CD proteinase and its comparison to the 3C proteinase.
    Davis GJ; Wang QM; Cox GA; Johnson RB; Wakulchik M; Dotson CA; Villarreal EC
    Arch Biochem Biophys; 1997 Oct; 346(1):125-30. PubMed ID: 9328292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease.
    Webber SE; Tikhe J; Worland ST; Fuhrman SA; Hendrickson TF; Matthews DA; Love RA; Patick AK; Meador JW; Ferre RA; Brown EL; DeLisle DM; Ford CE; Binford SL
    J Med Chem; 1996 Dec; 39(26):5072-82. PubMed ID: 8978838
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors.
    Dragovich PS; Zhou R; Webber SE; Prins TJ; Kwok AK; Okano K; Fuhrman SA; Zalman LS; Maldonado FC; Brown EL; Meador JW; Patick AK; Ford CE; Brothers MA; Binford SL; Matthews DA; Ferre RA; Worland ST
    Bioorg Med Chem Lett; 2000 Jan; 10(1):45-8. PubMed ID: 10636240
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.