BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 9651384)

  • 1. Lipid products of phosphoinositide 3-kinase and phosphatidylinositol 4',5'-bisphosphate are both required for ADP-dependent platelet spreading.
    Heraud JM; Racaud-Sultan C; Gironcel D; Albigès-Rizo C; Giacomini T; Roques S; Martel V; Breton-Douillon M; Perret B; Chap H
    J Biol Chem; 1998 Jul; 273(28):17817-23. PubMed ID: 9651384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.
    Lova P; Paganini S; Hirsch E; Barberis L; Wymann M; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2003 Jan; 278(1):131-8. PubMed ID: 12407113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase function.
    Rozenvayn N; Flaumenhaft R
    J Biol Chem; 2001 Jun; 276(25):22410-9. PubMed ID: 11304526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.
    Gratacap MP; Payrastre B; Viala C; Mauco G; Plantavid M; Chap H
    J Biol Chem; 1998 Sep; 273(38):24314-21. PubMed ID: 9733717
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
    Campus F; Lova P; Bertoni A; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2005 Jul; 280(26):24386-95. PubMed ID: 15863506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol.
    Tang X; Downes CP
    J Biol Chem; 1997 May; 272(22):14193-9. PubMed ID: 9162050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets.
    Zhang J; Falck JR; Reddy KK; Abrams CS; Zhao W; Rittenhouse SE
    J Biol Chem; 1995 Sep; 270(39):22807-10. PubMed ID: 7559410
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb)beta(3).
    Yap CL; Anderson KE; Hughan SC; Dopheide SM; Salem HH; Jackson SP
    Blood; 2002 Jan; 99(1):151-8. PubMed ID: 11756165
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of the platelet p47 phosphoprotein is mediated by the lipid products of phosphoinositide 3-kinase.
    Toker A; Bachelot C; Chen CS; Falck JR; Hartwig JH; Cantley LC; Kovacsovics TJ
    J Biol Chem; 1995 Dec; 270(49):29525-31. PubMed ID: 7493994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells.
    Willars GB; Nahorski SR; Challiss RA
    J Biol Chem; 1998 Feb; 273(9):5037-46. PubMed ID: 9478953
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism.
    Kauffenstein G; Bergmeier W; Eckly A; Ohlmann P; Léon C; Cazenave JP; Nieswandt B; Gachet C
    FEBS Lett; 2001 Sep; 505(2):281-90. PubMed ID: 11566191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation.
    Kovacsovics TJ; Bachelot C; Toker A; Vlahos CJ; Duckworth B; Cantley LC; Hartwig JH
    J Biol Chem; 1995 May; 270(19):11358-66. PubMed ID: 7744773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phospholipase C-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5-bisphoshate, in carbamylcholine-stimulated islets of langerhans.
    Mitchell CJ; Kelly MM; Blewitt M; Wilson JR; Biden TJ
    J Biol Chem; 2001 Jun; 276(22):19072-7. PubMed ID: 11274217
    [TBL] [Abstract][Full Text] [Related]  

  • 14. alphaIIb beta 3-integrin mediated adhesion of human platelets to a fibrinogen matrix triggers phospholipase C activation and phosphatidylinositol 3',4'-biphosphate accumulation.
    Gironcel D; Racaud-Sultan C; Payrastre B; Haricot M; Borchert G; Kieffer N; Breton M; Chap H
    FEBS Lett; 1996 Jul; 389(3):253-6. PubMed ID: 8766710
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of phosphatidylinositol 3,4-bisphosphate is regulated by protein-tyrosine phosphorylation but the p85 alpha subunit of phosphatidylinositol 3-kinase may not be a target for tyrosine kinases in thrombin-stimulated human platelets.
    Yatomi Y; Ozaki Y; Satoh K; Kume S
    Biochim Biophys Acta; 1994 Jun; 1212(3):337-44. PubMed ID: 8199204
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate.
    Zhang J; Banfić H; Straforini F; Tosi L; Volinia S; Rittenhouse SE
    J Biol Chem; 1998 Jun; 273(23):14081-4. PubMed ID: 9603905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Platelet-derived-growth-factor-induced signalling in human platelets: phosphoinositide-3-kinase-dependent inhibition of platelet activation.
    Selheim F; Fukami MH; Holmsen H; Vassbotn FS
    Biochem J; 2000 Sep; 350 Pt 2(Pt 2):469-75. PubMed ID: 10947961
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.
    Krymskaya VP; Penn RB; Orsini MJ; Scott PH; Plevin RJ; Walker TR; Eszterhas AJ; Amrani Y; Chilvers ER; Panettieri RA
    Am J Physiol; 1999 Jul; 277(1):L65-78. PubMed ID: 10409232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A platelet biomarker for assessing phosphoinositide 3-kinase inhibition during cancer chemotherapy.
    Bowers RK; Marder P; Green LJ; Horn CL; Faber AL; Thomas JE
    Mol Cancer Ther; 2007 Sep; 6(9):2600-7. PubMed ID: 17766838
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphoinositide 3-kinase gamma and p85/phosphoinositide 3-kinase in platelets. Relative activation by thrombin receptor or beta-phorbol myristate acetate and roles in promoting the ligand-binding function of alphaIIbbeta3 integrin.
    Zhang J; Zhang J; Shattil SJ; Cunningham MC; Rittenhouse SE
    J Biol Chem; 1996 Mar; 271(11):6265-72. PubMed ID: 8626420
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.