BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

63 related articles for article (PubMed ID: 9652956)

  • 1. [Biochemistry of presenilin 1].
    Takashima A
    Rinsho Shinkeigaku; 1997 Dec; 37(12):1097-8. PubMed ID: 9652956
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells.
    Takashima A; Sato M; Mercken M; Tanaka S; Kondo S; Honda T; Sato K; Murayama M; Noguchi K; Nakazato Y; Takahashi H
    Biochem Biophys Res Commun; 1996 Oct; 227(2):423-6. PubMed ID: 8878531
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.
    Mercken M; Takahashi H; Honda T; Sato K; Murayama M; Nakazato Y; Noguchi K; Imahori K; Takashima A
    FEBS Lett; 1996 Jul; 389(3):297-303. PubMed ID: 8766720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
    Podlisny MB; Citron M; Amarante P; Sherrington R; Xia W; Zhang J; Diehl T; Levesque G; Fraser P; Haass C; Koo EH; Seubert P; St George-Hyslop P; Teplow DB; Selkoe DJ
    Neurobiol Dis; 1997; 3(4):325-37. PubMed ID: 9173929
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.
    Citron M; Eckman CB; Diehl TS; Corcoran C; Ostaszewski BL; Xia W; Levesque G; St George Hyslop P; Younkin SG; Selkoe DJ
    Neurobiol Dis; 1998 Aug; 5(2):107-16. PubMed ID: 9746908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
    Levey AI; Heilman CJ; Lah JJ; Nash NR; Rees HD; Wakai M; Mirra SS; Rye DB; Nochlin D; Bird TD; Mufson EJ
    Ann Neurol; 1997 Jun; 41(6):742-53. PubMed ID: 9189035
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F; Czech C; Esclaire F; Elyaman W; Yardin C; Baclet MC; Touchet N; Tremp G; Pradier L; Hugon J
    J Neurosci Res; 2002 Aug; 69(4):530-9. PubMed ID: 12210846
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.
    Uemura K; Kitagawa N; Kohno R; Kuzuya A; Kageyama T; Chonabayashi K; Shibasaki H; Shimohama S
    J Neurosci Res; 2003 Oct; 74(2):184-91. PubMed ID: 14515347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mapping the APP/presenilin (PS) binding domains: the hydrophilic N-terminus of PS2 is sufficient for interaction with APP and can displace APP/PS1 interaction.
    Pradier L; Carpentier N; Delalonde L; Clavel N; Bock MD; Buée L; Mercken L; Tocqué B; Czech C
    Neurobiol Dis; 1999 Feb; 6(1):43-55. PubMed ID: 10078972
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T; Imaizumi K; Sato N; Miyoshi K; Kudo T; Hitomi J; Morihara T; Yoneda T; Gomi F; Mori Y; Nakano Y; Takeda J; Tsuda T; Itoyama Y; Murayama O; Takashima A; St George-Hyslop P; Takeda M; Tohyama M
    Nat Cell Biol; 1999 Dec; 1(8):479-85. PubMed ID: 10587643
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH; Hof PR; Chen X; Gluck K; Austin G; Younkin SG; Younkin LH; DeGasperi R; Gama Sosa MA; Robakis NK; Haroutunian V; Elder GA
    Exp Neurol; 2004 Aug; 188(2):224-37. PubMed ID: 15246822
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
    Li YM; Xu M; Lai MT; Huang Q; Castro JL; DiMuzio-Mower J; Harrison T; Lellis C; Nadin A; Neduvelil JG; Register RB; Sardana MK; Shearman MS; Smith AL; Shi XP; Yin KC; Shafer JA; Gardell SJ
    Nature; 2000 Jun; 405(6787):689-94. PubMed ID: 10864326
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex.
    Xia W; Ostaszewski BL; Kimberly WT; Rahmati T; Moore CL; Wolfe MS; Selkoe DJ
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):673-81. PubMed ID: 11114265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
    Hashimoto Y; Tsukamoto E; Niikura T; Yamagishi Y; Ishizaka M; Aiso S; Takashima A; Nishimoto I
    J Neurosci Res; 2004 Feb; 75(3):417-28. PubMed ID: 14743455
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The presenilin 1 C92S mutation increases abeta 42 production.
    Lewis PA; Perez-Tur J; Golde TE; Hardy J
    Biochem Biophys Res Commun; 2000 Oct; 277(1):261-3. PubMed ID: 11027672
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein.
    Hamano T; Mutoh T; Tabira T; Araki W; Kuriyama M; Mihara T; Yano S; Yamamoto H
    Brain Res Mol Brain Res; 2005 Jun; 137(1-2):70-6. PubMed ID: 15950763
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The coat protein complex II, COPII, protein Sec13 directly interacts with presenilin-1.
    Nielsen AL
    Biochem Biophys Res Commun; 2009 Oct; 388(3):571-5. PubMed ID: 19682973
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
    Sato N; Urano F; Yoon Leem J; Kim SH; Li M; Donoviel D; Bernstein A; Lee AS; Ron D; Veselits ML; Sisodia SS; Thinakaran G
    Nat Cell Biol; 2000 Dec; 2(12):863-70. PubMed ID: 11146649
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES; Martinez M; Brunkan AL; Goate A
    J Neurochem; 2005 Jan; 92(2):294-301. PubMed ID: 15663477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.