176 related articles for article (PubMed ID: 9654084)
1. A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
Kobayashi H; Sugino D; She MY; Ohi H; Hirashima Y; Shinohara H; Fujie M; Shibata K; Terao T
Eur J Biochem; 1998 May; 253(3):817-26. PubMed ID: 9654084
[TBL] [Abstract][Full Text] [Related]
2. [Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis].
Kobayashi H
Nihon Sanka Fujinka Gakkai Zasshi; 1996 Aug; 48(8):623-32. PubMed ID: 8808830
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Kobayashi H; Shinohara H; Fujie M; Gotoh J; Itoh M; Takeuchi K; Terao T
Int J Cancer; 1995 Nov; 63(3):455-62. PubMed ID: 7591248
[TBL] [Abstract][Full Text] [Related]
4. Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro.
Kobayashi H; Gotoh J; Hirashima Y; Fujie M; Sugino D; Terao T
J Biol Chem; 1995 Apr; 270(14):8361-6. PubMed ID: 7713945
[TBL] [Abstract][Full Text] [Related]
5. cDNA transfection of amino-terminal fragment of urokinase efficiently inhibits cancer cell invasion and metastasis.
Zhu F; Jia S; Xing G; Gao L; Zhang L; He F
DNA Cell Biol; 2001 May; 20(5):297-305. PubMed ID: 11410166
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.
Kobayashi H; Shinohara H; Takeuchi K; Itoh M; Fujie M; Saitoh M; Terao T
Cancer Res; 1994 Feb; 54(3):844-9. PubMed ID: 8306348
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of tumor cell invasion through matrigel by a peptide derived from the domain II region in urinary trypsin inhibition.
Kobayashi H; Gotoh J; Kanayama N; Hirashima Y; Terao T; Sugino D
Cancer Res; 1995 May; 55(9):1847-52. PubMed ID: 7728751
[TBL] [Abstract][Full Text] [Related]
8. Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Suzuki M; Kobayashi H; Tanaka Y; Hirashima Y; Kanayama N; Takei Y; Saga Y; Suzuki M; Itoh H; Terao T
Int J Cancer; 2003 Apr; 104(3):289-302. PubMed ID: 12569552
[TBL] [Abstract][Full Text] [Related]
9. Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Kobayashi H; Shinohara H; Ohi H; Sugimura M; Terao T; Fujie M
Clin Exp Metastasis; 1994 Mar; 12(2):117-28. PubMed ID: 8306525
[TBL] [Abstract][Full Text] [Related]
10. A hybrid protein of urokinase growth-factor domain and plasminogen-activator inhibitor type 2 inhibits urokinase activity and binds to the urokinase receptor.
Ballance DJ; Marshall JM; Cottingham IR; Steven J; Berry SJ; Cederholm-Williams SA; Goodey AR; Courtney M
Eur J Biochem; 1992 Jul; 207(1):177-83. PubMed ID: 1321039
[TBL] [Abstract][Full Text] [Related]
11. A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Kobayashi H; Suzuki M; Kanayama N; Terao T
Clin Exp Metastasis; 2004; 21(2):159-66. PubMed ID: 15168733
[TBL] [Abstract][Full Text] [Related]
12. Overexpression of a hybrid gene consisting of the amino-terminal fragment of urokinase and carboxyl-terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro.
Takei Y; Mizukami H; Saga Y; Kobayashi H; Suzuki M; Matsushita T; Ozawa K; Suzuki M
Int J Cancer; 2005 Jan; 113(1):54-8. PubMed ID: 15386422
[TBL] [Abstract][Full Text] [Related]
13. Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells.
Kobayashi H; Fujie M; Shinohara H; Ohi H; Sugimura M; Terao T
Int J Cancer; 1994 May; 57(3):378-84. PubMed ID: 8168999
[TBL] [Abstract][Full Text] [Related]
14. Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis.
Tanaka Y; Kobayashi H; Suzuki M; Hirashima Y; Kanayama N; Terao T
Int J Cancer; 2004 Apr; 109(3):336-47. PubMed ID: 14961570
[TBL] [Abstract][Full Text] [Related]
15. A hybrid protein comprising ATF domain of pro-UK and VAS, an angiogenesis inhibitor, is a potent candidate for targeted cancer therapy.
Sun Q; Xu Q; Dong X; Cao L; Huang X; Hu Q; Hua ZC
Int J Cancer; 2008 Aug; 123(4):942-50. PubMed ID: 18528863
[TBL] [Abstract][Full Text] [Related]
16. High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread.
Sato S; Kopitz C; Schmalix WA; Muehlenweg B; Kessler H; Schmitt M; Krüger A; Magdolen V
FEBS Lett; 2002 Sep; 528(1-3):212-6. PubMed ID: 12297307
[TBL] [Abstract][Full Text] [Related]
17. Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Kobayashi H; Gotoh J; Terao T
Eur J Cell Biol; 1996 Dec; 71(4):380-6. PubMed ID: 8980909
[TBL] [Abstract][Full Text] [Related]
18. A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
Kobayashi H; Suzuki M; Tanaka Y; Kanayama N; Terao T
J Biol Chem; 2003 Mar; 278(10):7790-9. PubMed ID: 12496270
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.
Suzuki M; Kobayashi H; Kanayama N; Saga Y; Suzuki M; Lin CY; Dickson RB; Terao T
J Biol Chem; 2004 Apr; 279(15):14899-908. PubMed ID: 14747469
[TBL] [Abstract][Full Text] [Related]
20. Suppression of urokinase expression and tumor metastasis by bikunin overexpression [mini-review].
Kobayashi H
Hum Cell; 2001 Sep; 14(3):233-6. PubMed ID: 11774742
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
