348 related articles for article (PubMed ID: 9657673)
1. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
Long SB; Casey PJ; Beese LS
Biochemistry; 1998 Jul; 37(27):9612-8. PubMed ID: 9657673
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase.
Turek-Etienne TC; Strickland CL; Distefano MD
Biochemistry; 2003 Apr; 42(13):3716-24. PubMed ID: 12667062
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue.
Strickland CL; Windsor WT; Syto R; Wang L; Bond R; Wu Z; Schwartz J; Le HV; Beese LS; Weber PC
Biochemistry; 1998 Nov; 37(47):16601-11. PubMed ID: 9843427
[TBL] [Abstract][Full Text] [Related]
4. Protein farnesyltransferase: structure and implications for substrate binding.
Dunten P; Kammlott U; Crowther R; Weber D; Palermo R; Birktoft J
Biochemistry; 1998 Jun; 37(22):7907-12. PubMed ID: 9609683
[TBL] [Abstract][Full Text] [Related]
5. Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.
Troutman JM; Subramanian T; Andres DA; Spielmann HP
Biochemistry; 2007 Oct; 46(40):11310-21. PubMed ID: 17854205
[TBL] [Abstract][Full Text] [Related]
6. Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation.
Pickett JS; Bowers KE; Hartman HL; Fu HW; Embry AC; Casey PJ; Fierke CA
Biochemistry; 2003 Aug; 42(32):9741-8. PubMed ID: 12911316
[TBL] [Abstract][Full Text] [Related]
7. Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase.
Reigard SA; Zahn TJ; Haworth KB; Hicks KA; Fierke CA; Gibbs RA
Biochemistry; 2005 Aug; 44(33):11214-23. PubMed ID: 16101305
[TBL] [Abstract][Full Text] [Related]
8. Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release.
Troutman JM; Andres DA; Spielmann HP
Biochemistry; 2007 Oct; 46(40):11299-309. PubMed ID: 17877368
[TBL] [Abstract][Full Text] [Related]
9. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
Reid TS; Terry KL; Casey PJ; Beese LS
J Mol Biol; 2004 Oct; 343(2):417-33. PubMed ID: 15451670
[TBL] [Abstract][Full Text] [Related]
10. Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Terry KL; Casey PJ; Beese LS
Biochemistry; 2006 Aug; 45(32):9746-55. PubMed ID: 16893176
[TBL] [Abstract][Full Text] [Related]
11. Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.
Subramanian T; Liu S; Troutman JM; Andres DA; Spielmann HP
Chembiochem; 2008 Nov; 9(17):2872-82. PubMed ID: 18985644
[TBL] [Abstract][Full Text] [Related]
12. Photoaffinity labeling of yeast farnesyl protein transferase and enzymatic synthesis of a Ras protein incorporating a photoactive isoprenoid.
Edelstein RL; Distefano MD
Biochem Biophys Res Commun; 1997 Jun; 235(2):377-82. PubMed ID: 9199201
[TBL] [Abstract][Full Text] [Related]
13. Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups.
Micali E; Chehade KA; Isaacs RJ; Andres DA; Spielmann HP
Biochemistry; 2001 Oct; 40(41):12254-65. PubMed ID: 11591144
[TBL] [Abstract][Full Text] [Related]
14. Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies.
Wu Z; Demma M; Strickland CL; Radisky ES; Poulter CD; Le HV; Windsor WT
Biochemistry; 1999 Aug; 38(35):11239-49. PubMed ID: 10471273
[TBL] [Abstract][Full Text] [Related]
15. Computational and conformational evaluation of FTase alternative substrates: insight into a novel enzyme binding pocket.
Henriksen BS; Zahn TJ; Evanseck JD; Firestine SM; Gibbs RA
J Chem Inf Model; 2005; 45(4):1047-52. PubMed ID: 16045300
[TBL] [Abstract][Full Text] [Related]
16. The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
Long SB; Casey PJ; Beese LS
Structure; 2000 Feb; 8(2):209-22. PubMed ID: 10673434
[TBL] [Abstract][Full Text] [Related]
17. Reaction path of protein farnesyltransferase at atomic resolution.
Long SB; Casey PJ; Beese LS
Nature; 2002 Oct; 419(6907):645-50. PubMed ID: 12374986
[TBL] [Abstract][Full Text] [Related]
18. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase.
Chehade KA; Kiegiel K; Isaacs RJ; Pickett JS; Bowers KE; Fierke CA; Andres DA; Spielmann HP
J Am Chem Soc; 2002 Jul; 124(28):8206-19. PubMed ID: 12105898
[TBL] [Abstract][Full Text] [Related]
19. Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state.
Huang C; Hightower KE; Fierke CA
Biochemistry; 2000 Mar; 39(10):2593-602. PubMed ID: 10704208
[TBL] [Abstract][Full Text] [Related]
20. Positively charged side chains in protein farnesyltransferase enhance catalysis by stabilizing the formation of the diphosphate leaving group.
Bowers KE; Fierke CA
Biochemistry; 2004 May; 43(18):5256-65. PubMed ID: 15122891
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
