These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 9657673)

  • 1. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
    Long SB; Casey PJ; Beese LS
    Biochemistry; 1998 Jul; 37(27):9612-8. PubMed ID: 9657673
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase.
    Turek-Etienne TC; Strickland CL; Distefano MD
    Biochemistry; 2003 Apr; 42(13):3716-24. PubMed ID: 12667062
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue.
    Strickland CL; Windsor WT; Syto R; Wang L; Bond R; Wu Z; Schwartz J; Le HV; Beese LS; Weber PC
    Biochemistry; 1998 Nov; 37(47):16601-11. PubMed ID: 9843427
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein farnesyltransferase: structure and implications for substrate binding.
    Dunten P; Kammlott U; Crowther R; Weber D; Palermo R; Birktoft J
    Biochemistry; 1998 Jun; 37(22):7907-12. PubMed ID: 9609683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.
    Troutman JM; Subramanian T; Andres DA; Spielmann HP
    Biochemistry; 2007 Oct; 46(40):11310-21. PubMed ID: 17854205
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation.
    Pickett JS; Bowers KE; Hartman HL; Fu HW; Embry AC; Casey PJ; Fierke CA
    Biochemistry; 2003 Aug; 42(32):9741-8. PubMed ID: 12911316
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase.
    Reigard SA; Zahn TJ; Haworth KB; Hicks KA; Fierke CA; Gibbs RA
    Biochemistry; 2005 Aug; 44(33):11214-23. PubMed ID: 16101305
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release.
    Troutman JM; Andres DA; Spielmann HP
    Biochemistry; 2007 Oct; 46(40):11299-309. PubMed ID: 17877368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
    Reid TS; Terry KL; Casey PJ; Beese LS
    J Mol Biol; 2004 Oct; 343(2):417-33. PubMed ID: 15451670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
    Terry KL; Casey PJ; Beese LS
    Biochemistry; 2006 Aug; 45(32):9746-55. PubMed ID: 16893176
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.
    Subramanian T; Liu S; Troutman JM; Andres DA; Spielmann HP
    Chembiochem; 2008 Nov; 9(17):2872-82. PubMed ID: 18985644
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Photoaffinity labeling of yeast farnesyl protein transferase and enzymatic synthesis of a Ras protein incorporating a photoactive isoprenoid.
    Edelstein RL; Distefano MD
    Biochem Biophys Res Commun; 1997 Jun; 235(2):377-82. PubMed ID: 9199201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups.
    Micali E; Chehade KA; Isaacs RJ; Andres DA; Spielmann HP
    Biochemistry; 2001 Oct; 40(41):12254-65. PubMed ID: 11591144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies.
    Wu Z; Demma M; Strickland CL; Radisky ES; Poulter CD; Le HV; Windsor WT
    Biochemistry; 1999 Aug; 38(35):11239-49. PubMed ID: 10471273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computational and conformational evaluation of FTase alternative substrates: insight into a novel enzyme binding pocket.
    Henriksen BS; Zahn TJ; Evanseck JD; Firestine SM; Gibbs RA
    J Chem Inf Model; 2005; 45(4):1047-52. PubMed ID: 16045300
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
    Long SB; Casey PJ; Beese LS
    Structure; 2000 Feb; 8(2):209-22. PubMed ID: 10673434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reaction path of protein farnesyltransferase at atomic resolution.
    Long SB; Casey PJ; Beese LS
    Nature; 2002 Oct; 419(6907):645-50. PubMed ID: 12374986
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase.
    Chehade KA; Kiegiel K; Isaacs RJ; Pickett JS; Bowers KE; Fierke CA; Andres DA; Spielmann HP
    J Am Chem Soc; 2002 Jul; 124(28):8206-19. PubMed ID: 12105898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state.
    Huang C; Hightower KE; Fierke CA
    Biochemistry; 2000 Mar; 39(10):2593-602. PubMed ID: 10704208
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Positively charged side chains in protein farnesyltransferase enhance catalysis by stabilizing the formation of the diphosphate leaving group.
    Bowers KE; Fierke CA
    Biochemistry; 2004 May; 43(18):5256-65. PubMed ID: 15122891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.