BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

60 related articles for article (PubMed ID: 9667955)

  • 1. Enhancement of oral absorption in selective 5-HT1D receptor agonists: fluorinated 3-[3-(piperidin-1-yl)propyl]indoles.
    Castro JL; Collins I; Russell MG; Watt AP; Sohal B; Rathbone D; Beer MS; Stanton JA
    J Med Chem; 1998 Jul; 41(15):2667-70. PubMed ID: 9667955
    [No Abstract]   [Full Text] [Related]  

  • 2. 3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.
    Chambers MS; Street LJ; Goodacre S; Hobbs SC; Hunt P; Jelley RA; Matassa VG; Reeve AJ; Sternfeld F; Beer MS; Stanton JA; Rathbone D; Watt AP; MacLeod AM
    J Med Chem; 1999 Feb; 42(4):691-705. PubMed ID: 10052976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F; Guiblin AR; Jelley RA; Matassa VG; Reeve AJ; Hunt PA; Beer MS; Heald A; Stanton JA; Sohal B; Watt AP; Street LJ
    J Med Chem; 1999 Feb; 42(4):677-90. PubMed ID: 10052975
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.
    van Niel MB; Collins I; Beer MS; Broughton HB; Cheng SK; Goodacre SC; Heald A; Locker KL; MacLeod AM; Morrison D; Moyes CR; O'Connor D; Pike A; Rowley M; Russell MG; Sohal B; Stanton JA; Thomas S; Verrier H; Watt AP; Castro JL
    J Med Chem; 1999 Jun; 42(12):2087-104. PubMed ID: 10377215
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3-[2-(Pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype.
    Castro JL; Street LJ; Guiblin AR; Jelley RA; Russell MG; Sternfeld F; Beer MS; Stanton JA; Matassa VG
    J Med Chem; 1997 Oct; 40(22):3497-500. PubMed ID: 9357514
    [No Abstract]   [Full Text] [Related]  

  • 6. Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide.
    Choi SK; Green D; Ho A; Klein U; Marquess D; Taylor R; Turner SD
    J Med Chem; 2008 Jun; 51(12):3609-16. PubMed ID: 18507369
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.
    Vacher B; Bonnaud B; Funes P; Jubault N; Koek W; Assié MB; Cosi C; Kleven M
    J Med Chem; 1999 May; 42(9):1648-60. PubMed ID: 10229633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.
    MacLeod AM; Street LJ; Reeve AJ; Jelley RA; Sternfeld F; Beer MS; Stanton JA; Watt AP; Rathbone D; Matassa VG
    J Med Chem; 1997 Oct; 40(22):3501-3. PubMed ID: 9357515
    [No Abstract]   [Full Text] [Related]  

  • 9. 4-Hydroxy-1-[3-(5-(1,2,4-triazol-4-yl)-1H-indol-3-yl)propyl]piperidines: selective h5-HT1D agonists for the treatment of migraine.
    Bourrain S; Neduvelil JG; Beer MS; Stanton JA; Showell GA; MacLeod AM
    Bioorg Med Chem Lett; 1999 Dec; 9(23):3369-74. PubMed ID: 10612601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
    Mattsson C; Sonesson C; Sandahl A; Greiner HE; Gassen M; Plaschke J; Leibrock J; Böttcher H
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4230-4. PubMed ID: 16055331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists.
    Russell MG; Matassa VG; Pengilley RR; van Niel MB; Sohal B; Watt AP; Hitzel L; Beer MS; Stanton JA; Broughton HB; Castro JL
    J Med Chem; 1999 Dec; 42(24):4981-5001. PubMed ID: 10585208
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 8-Piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines: potent, selective, orally bioavailable 5-HT1 receptor ligands.
    Heightman TD; Gaster LM; Pardoe SL; Pilleux JP; Hadley MS; Middlemiss DN; Price GW; Roberts C; Scott CM; Watson JM; Gordon LJ; Holland VA; Powles J; Riley GJ; Stean TO; Trail BK; Upton N; Austin NE; Ayrton AD; Coleman T; Cutler L
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4370-4. PubMed ID: 16039851
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
    Holenz J; Mercè R; Díaz JL; Guitart X; Codony X; Dordal A; Romero G; Torrens A; Mas J; Andaluz B; Hernández S; Monroy X; Sánchez E; Hernández E; Pérez R; Cubí R; Sanfeliu O; Buschmann H
    J Med Chem; 2005 Mar; 48(6):1781-95. PubMed ID: 15771424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists.
    Holmberg P; Sohn D; Leideborg R; Caldirola P; Zlatoidsky P; Hanson S; Mohell N; Rosqvist S; Nordvall G; Johansson AM; Johansson R
    J Med Chem; 2004 Jul; 47(16):3927-30. PubMed ID: 15267230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro and in vivo pharmacological characterization of PF-01354082, a novel partial agonist selective for the 5-HT(4) receptor.
    Mikami T; Komada T; Sugimoto H; Suzuki K; Ohmi T; Kimura N; Naganeo R; Nakata E; Nakatani K; Toga T; Eda H; Sakakibara M
    Eur J Pharmacol; 2009 May; 609(1-3):5-12. PubMed ID: 19285067
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole.
    May JA; Chen HH; Rusinko A; Lynch VM; Sharif NA; McLaughlin MA
    J Med Chem; 2003 Sep; 46(19):4188-95. PubMed ID: 12954071
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of new serotonin 5-HT7 receptor ligands. Determinants of 5-HT7/5-HT1A receptor selectivity.
    Medina RA; Sallander J; Benhamú B; Porras E; Campillo M; Pardo L; López-Rodríguez ML
    J Med Chem; 2009 Apr; 52(8):2384-92. PubMed ID: 19326916
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel actions of inverse agonists on 5-HT2C receptor systems.
    Berg KA; Stout BD; Cropper JD; Maayani S; Clarke WP
    Mol Pharmacol; 1999 May; 55(5):863-72. PubMed ID: 10220565
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT1A partial agonists.
    Dounay AB; Barta NS; Bikker JA; Borosky SA; Campbell BM; Crawford T; Denny L; Evans LM; Gray DL; Lee P; Lenoir EA; Xu W
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1159-63. PubMed ID: 19147349
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors.
    Watson J; Brough S; Coldwell MC; Gager T; Ho M; Hunter AJ; Jerman J; Middlemiss DN; Riley GJ; Brown AM
    Br J Pharmacol; 1998 Dec; 125(7):1413-20. PubMed ID: 9884068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.