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6. Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. Troutman JM; Chehade KA; Kiegiel K; Andres DA; Spielmann HP Bioorg Med Chem Lett; 2004 Oct; 14(19):4979-82. PubMed ID: 15341963 [TBL] [Abstract][Full Text] [Related]
7. Novel limonene phosphonate and farnesyl diphosphate analogues: design, synthesis, and evaluation as potential protein-farnesyl transferase inhibitors. Eummer JT; Gibbs BS; Zahn TJ; Sebolt-Leopold JS; Gibbs RA Bioorg Med Chem; 1999 Feb; 7(2):241-50. PubMed ID: 10218815 [TBL] [Abstract][Full Text] [Related]
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9. Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein: farnesyl transferase. Cohen LH; Pieterman E; van Leeuwen RE; Du J; Negre-Aminou P; Valentijn AR; Overhand M; van der Marel GA; van Boom JH Biochem Pharmacol; 1999 Feb; 57(4):365-73. PubMed ID: 9933024 [TBL] [Abstract][Full Text] [Related]
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11. Inhibitors of farnesyl:protein transferase--a possible cancer chemotherapeutic. Scholten JD; Zimmerman K; Oxender M; Sebolt-Leopold J; Gowan R; Leonard D; Hupe DJ Bioorg Med Chem; 1996 Sep; 4(9):1537-43. PubMed ID: 8894110 [TBL] [Abstract][Full Text] [Related]
12. Preparation of alpha-phosphono lactams via electrophilic phosphorus reagents: an application in the synthesis of lactam-based farnesyl transferase Inhibitors. Du Y; Wiemer DF J Org Chem; 2002 Aug; 67(16):5709-17. PubMed ID: 12153273 [TBL] [Abstract][Full Text] [Related]
13. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. Chehade KA; Kiegiel K; Isaacs RJ; Pickett JS; Bowers KE; Fierke CA; Andres DA; Spielmann HP J Am Chem Soc; 2002 Jul; 124(28):8206-19. PubMed ID: 12105898 [TBL] [Abstract][Full Text] [Related]
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17. New synthetic methodology for the construction of 7-substituted farnesyl diphosphate analogs. Placzek AT; Gibbs RA Org Lett; 2011 Jul; 13(14):3576-9. PubMed ID: 21699139 [TBL] [Abstract][Full Text] [Related]
18. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase. Lingham RB; Silverman KC; Jayasuriya H; Kim BM; Amo SE; Wilson FR; Rew DJ; Schaber MD; Bergstrom JD; Koblan KS; Graham SL; Kohl NE; Gibbs JB; Singh SB J Med Chem; 1998 Nov; 41(23):4492-501. PubMed ID: 9804689 [TBL] [Abstract][Full Text] [Related]
19. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents. Cohen LH; Valentijn AR; Roodenburg L; Van Leeuwen RE; Huisman RH; Lutz RJ; Van der Marel GA; Van Boom JH Biochem Pharmacol; 1995 Mar; 49(6):839-45. PubMed ID: 7702642 [TBL] [Abstract][Full Text] [Related]
20. Photoaffinity labeling of yeast farnesyl protein transferase and enzymatic synthesis of a Ras protein incorporating a photoactive isoprenoid. Edelstein RL; Distefano MD Biochem Biophys Res Commun; 1997 Jun; 235(2):377-82. PubMed ID: 9199201 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]