BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 9685218)

  • 1. Difference in dominant negative activities between mutant thyroid hormone receptors alpha1 and beta1 with an identical truncation in the extreme carboxyl-terminal tau4 domain.
    Nishiyama K; Andoh S; Kitahara A; Natsume H; Mikami T; Genma R; Nakamura H
    Mol Cell Endocrinol; 1998 Mar; 138(1-2):95-104. PubMed ID: 9685218
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional properties of a mutant T3 receptor beta (R338W) identified in a subject with pituitary resistance to thyroid hormone.
    Sasaki S; Nakamura H; Tagami T; Miyoshi Y; Nakao K
    Mol Cell Endocrinol; 1995 Aug; 113(1):109-17. PubMed ID: 8674808
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Mol Endocrinol; 1993 Oct; 7(10):1319-30. PubMed ID: 8264663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R; Zhu XG; Pineda MA; Cheng SY; Weintraub BD
    Mol Med; 1995 Mar; 1(3):306-19. PubMed ID: 8529109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA alpha 2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition.
    Meier-Heusler SC; Zhu X; Juge-Aubry C; Pernin A; Burger AG; Cheng SY; Meier CA
    Mol Cell Endocrinol; 1995 Jan; 107(1):55-66. PubMed ID: 7796935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG; Yu CL; McPhie P; Wong R; Cheng SY
    Endocrinology; 1996 Feb; 137(2):712-21. PubMed ID: 8593822
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA; Parkison C; Chen A; Ashizawa K; Meier-Heusler SC; Muchmore P; Cheng SY; Weintraub BD
    J Clin Invest; 1993 Oct; 92(4):1986-93. PubMed ID: 8408652
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Similar ligand-induced conformational changes of thyroid hormone receptors regulate homo- and heterodimeric functions.
    Bendik I; Pfahl M
    J Biol Chem; 1995 Feb; 270(7):3107-14. PubMed ID: 7852392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Endocrinology; 1996 Jul; 137(7):2833-41. PubMed ID: 8770904
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dominant-negative mutant thyroid hormone receptors prevent transcription from Xenopus thyroid hormone receptor beta gene promoter in response to thyroid hormone in Xenopus tadpoles in vivo.
    Ulisse S; Esslemont G; Baker BS; Krishna V; Chatterjee K; Tata JR
    Proc Natl Acad Sci U S A; 1996 Feb; 93(3):1205-9. PubMed ID: 8577741
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y; Nagaya T; Tsukaguchi H; Takamatsu J; Seo H
    Endocrinology; 1996 Oct; 137(10):4082-6. PubMed ID: 8828460
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spectrum of transcriptional, dimerization, and dominant negative properties of twenty different mutant thyroid hormone beta-receptors in thyroid hormone resistance syndrome.
    Collingwood TN; Adams M; Tone Y; Chatterjee VK
    Mol Endocrinol; 1994 Sep; 8(9):1262-77. PubMed ID: 7838159
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A; Miyamoto T; Refetoff S; DeGroot LJ
    Mol Endocrinol; 1990 Dec; 4(12):1988-94. PubMed ID: 2082193
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the thyroid hormone response element in the skeletal alpha-actin gene: negative regulation of T3 receptor binding by the retinoid X receptor.
    Muscat GE; Griggs R; Downes M; Emery J
    Cell Growth Differ; 1993 Apr; 4(4):269-79. PubMed ID: 8388243
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T; Suzuki S; Liu RT; DeGroot LJ
    J Clin Endocrinol Metab; 1995 Jul; 80(7):2033-40. PubMed ID: 7608251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dominant negative and DNA-binding properties of mutant thyroid hormone receptors that are defective in homodimerization but not heterodimerization.
    Kitajima K; Nagaya T; Jameson JL
    Thyroid; 1995 Oct; 5(5):343-53. PubMed ID: 8563470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription.
    Suen CS; Yen PM; Chin WW
    J Biol Chem; 1994 Jan; 269(2):1314-22. PubMed ID: 8288596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retinoid X receptor-alpha and apolipoprotein AI regulatory protein 1 differentially modulate 3,5,3'-triiodothyronine-induced transcription.
    Rhee M; Ikeda M; Chin WW
    Endocrinology; 1995 Jun; 136(6):2697-704. PubMed ID: 7750494
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.