120 related articles for article (PubMed ID: 9685244)
1. Bis-substituted malonic acid hydroxamate derivatives as inhibitors of human neutrophil collagenase (MMP8).
Graf von Roedern E; Brandstetter H; Engh RA; Bode W; Grams F; Moroder L
J Med Chem; 1998 Jul; 41(16):3041-7. PubMed ID: 9685244
[TBL] [Abstract][Full Text] [Related]
2. Structure of malonic acid-based inhibitors bound to human neutrophil collagenase. A new binding mode explains apparently anomalous data.
Brandstetter H; Engh RA; Von Roedern EG; Moroder L; Huber R; Bode W; Grams F
Protein Sci; 1998 Jun; 7(6):1303-9. PubMed ID: 9655333
[TBL] [Abstract][Full Text] [Related]
3. Design and synthesis of malonic acid-based inhibitors of human neutrophil collagenase (MMP8).
Graf von Roedern E; Grams F; Brandstetter H; Moroder L
J Med Chem; 1998 Jan; 41(3):339-45. PubMed ID: 9464365
[TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases.
Pikul S; McDow Dunham KL; Almstead NG; De B; Natchus MG; Anastasio MV; McPhail SJ; Snider CE; Taiwo YO; Chen L; Dunaway CM; Gu F; Mieling GE
J Med Chem; 1999 Jan; 42(1):87-94. PubMed ID: 9888835
[TBL] [Abstract][Full Text] [Related]
5. High-resolution solution structure of the catalytic fragment of human collagenase-3 (MMP-13) complexed with a hydroxamic acid inhibitor.
Moy FJ; Chanda PK; Chen JM; Cosmi S; Edris W; Levin JI; Powers R
J Mol Biol; 2000 Sep; 302(3):671-89. PubMed ID: 10986126
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes.
Chen L; Rydel TJ; Gu F; Dunaway CM; Pikul S; Dunham KM; Barnett BL
J Mol Biol; 1999 Oct; 293(3):545-57. PubMed ID: 10543949
[TBL] [Abstract][Full Text] [Related]
7. X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
Grams F; Reinemer P; Powers JC; Kleine T; Pieper M; Tschesche H; Huber R; Bode W
Eur J Biochem; 1995 Mar; 228(3):830-41. PubMed ID: 7737183
[TBL] [Abstract][Full Text] [Related]
8. Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453.
Kohno T; Hochigai H; Yamashita E; Tsukihara T; Kanaoka M
Biochem Biophys Res Commun; 2006 May; 344(1):315-22. PubMed ID: 16603129
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor.
Rowsell S; Hawtin P; Minshull CA; Jepson H; Brockbank SM; Barratt DG; Slater AM; McPheat WL; Waterson D; Henney AM; Pauptit RA
J Mol Biol; 2002 May; 319(1):173-81. PubMed ID: 12051944
[TBL] [Abstract][Full Text] [Related]
10. Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes.
Huguet F; Melet A; Alves de Sousa R; Lieutaud A; Chevalier J; Maigre L; Deschamps P; Tomas A; Leulliot N; Pages JM; Artaud I
ChemMedChem; 2012 Jun; 7(6):1020-30. PubMed ID: 22489069
[TBL] [Abstract][Full Text] [Related]
11. Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
Noe MC; Natarajan V; Snow SL; Wolf-Gouveia LA; Mitchell PG; Lopresti-Morrow L; Reeves LM; Yocum SA; Otterness I; Bliven MA; Carty TJ; Barberia JT; Sweeney FJ; Liras JL; Vaughn M
Bioorg Med Chem Lett; 2005 Jul; 15(14):3385-8. PubMed ID: 15953722
[TBL] [Abstract][Full Text] [Related]
12. Binding preferences of hydroxamate inhibitors of the matrix metalloproteinase human fibroblast collagenase.
Toba S; Damodaran KV; Merz KM
J Med Chem; 1999 Apr; 42(7):1225-34. PubMed ID: 10197966
[TBL] [Abstract][Full Text] [Related]
13. Structure of recombinant mouse collagenase-3 (MMP-13).
Botos I; Meyer E; Swanson SM; Lemaître V; Eeckhout Y; Meyer EF
J Mol Biol; 1999 Oct; 292(4):837-44. PubMed ID: 10525409
[TBL] [Abstract][Full Text] [Related]
14. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.
Grembecka J; Mucha A; Cierpicki T; Kafarski P
J Med Chem; 2003 Jun; 46(13):2641-55. PubMed ID: 12801228
[TBL] [Abstract][Full Text] [Related]
15. The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors.
Chirgadze NY; Sall DJ; Briggs SL; Clawson DK; Zhang M; Smith GF; Schevitz RW
Protein Sci; 2000 Jan; 9(1):29-36. PubMed ID: 10739244
[TBL] [Abstract][Full Text] [Related]
16. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
Costanzo MJ; Almond HR; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Corcoran TW; Giardino EC; Kauffman JA; Lewis JM; de Garavilla L; Haertlein BJ; Maryanoff BE
J Med Chem; 2005 Mar; 48(6):1984-2008. PubMed ID: 15771442
[TBL] [Abstract][Full Text] [Related]
17. NMR solution structure of the catalytic fragment of human fibroblast collagenase complexed with a sulfonamide derivative of a hydroxamic acid compound.
Moy FJ; Chanda PK; Chen JM; Cosmi S; Edris W; Skotnicki JS; Wilhelm J; Powers R
Biochemistry; 1999 Jun; 38(22):7085-96. PubMed ID: 10353819
[TBL] [Abstract][Full Text] [Related]
18. (R)-3-Amidinophenylalanine-derived inhibitors of factor Xa with a novel active-site binding mode.
Mueller MM; Sperl S; Stürzebecher J; Bode W; Moroder L
Biol Chem; 2002; 383(7-8):1185-91. PubMed ID: 12437104
[TBL] [Abstract][Full Text] [Related]
19. A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs.
Rossello A; Nuti E; Catalani MP; Carelli P; Orlandini E; Rapposelli S; Tuccinardi T; Atkinson SJ; Murphy G; Balsamo A
Bioorg Med Chem Lett; 2005 May; 15(9):2311-4. PubMed ID: 15837315
[TBL] [Abstract][Full Text] [Related]
20. Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H2 synthase peroxidase activity.
Lee J; Chubb AJ; Moman E; McLoughlin BM; Sharkey CT; Kelly JG; Nolan KB; Devocelle M; Fitzgerald DJ
Org Biomol Chem; 2005 Oct; 3(20):3678-85. PubMed ID: 16211102
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
