BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 9685249)

  • 1. Synthesis of 7-arylmorphinans. Probing the "address" requirements for selectivity at opioid delta receptors.
    Gao P; Larson DL; Portoghese PS
    J Med Chem; 1998 Jul; 41(16):3091-8. PubMed ID: 9685249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 14-Desoxy analogues of naltrindole and 7-spiroindanyloxymorphone: the role of the 14-hydroxy group at delta opioid receptors.
    Kshirsagar TA; Fang X; Portoghese PS
    J Med Chem; 1998 Jul; 41(14):2657-60. PubMed ID: 9651172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
    Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
    J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
    Ananthan S; Khare NK; Saini SK; Seitz LE; Bartlett JL; Davis P; Dersch CM; Porreca F; Rothman RB; Bilsky EJ
    J Med Chem; 2004 Mar; 47(6):1400-12. PubMed ID: 14998329
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors.
    Ohkawa S; DiGiacomo B; Larson DL; Takemori AE; Portoghese PS
    J Med Chem; 1997 May; 40(11):1720-5. PubMed ID: 9171881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands.
    Fang X; Larson DL; Portoghese PS
    J Med Chem; 1997 Sep; 40(19):3064-70. PubMed ID: 9301669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 7-Arylidenenaltrexones as selective delta1 opioid receptor antagonists.
    Ohkawa S; Portoghese PS
    J Med Chem; 1998 Oct; 41(21):4177-80. PubMed ID: 9767654
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of naltrexone-derived delta-opioid antagonists. Role of conformation of the delta address moiety.
    Portoghese PS; Sultana M; Moe ST; Takemori AE
    J Med Chem; 1994 Mar; 37(5):579-85. PubMed ID: 8126697
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.
    McLamore S; Ullrich T; Rothman RB; Xu H; Dersch C; Coop A; Davis P; Porreca F; Jacobson AE; Rice KC
    J Med Chem; 2001 Apr; 44(9):1471-4. PubMed ID: 11311071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. delta Opioid affinity and selectivity of 4-hydroxy-3-methoxyindolomorphinan analogues related to naltrindole.
    Coop A; Rothman RB; Dersch C; Partilla J; Porreca F; Davis P; Jacobson AE; Rice KC
    J Med Chem; 1999 May; 42(9):1673-9. PubMed ID: 10229636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BU48: a novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice.
    Broom DC; Guo L; Coop A; Husbands SM; Lewis JW; Woods JH; Traynor JR
    J Pharmacol Exp Ther; 2000 Sep; 294(3):1195-200. PubMed ID: 10945877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design of peptidomimetic delta opioid receptor antagonists using the message-address concept.
    Portoghese PS; Sultana M; Takemori AE
    J Med Chem; 1990 Jun; 33(6):1714-20. PubMed ID: 2160538
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Opioid agonist and antagonist activities of morphindoles related to naltrindole.
    Portoghese PS; Larson DL; Sultana M; Takemori AE
    J Med Chem; 1992 Nov; 35(23):4325-9. PubMed ID: 1333013
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and delta-opioid receptor antagonist activity of a naltrindole analogue with a regioisomeric indole moiety.
    Portoghese PS; Ohkawa S; Moe ST; Takemori AE
    J Med Chem; 1994 Jun; 37(12):1886-8. PubMed ID: 8021929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.
    Ananthan S; Kezar HS; Saini SK; Khare NK; Davis P; Dersch CM; Porreca F; Rothman RB
    Bioorg Med Chem Lett; 2003 Feb; 13(3):529-32. PubMed ID: 12565965
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of novel opioid ligands with a C-homomorphinan skeleton.
    Ishikawa K; Mochizuki Y; Hirayama S; Nemoto T; Nagai K; Itoh K; Fujii H
    Bioorg Med Chem; 2016 May; 24(10):2199-205. PubMed ID: 27079125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Side chain methyl substitution in the delta-opioid receptor antagonist TIPP has an important effect on the activity profile.
    Tourwé D; Mannekens E; Diem TN; Verheyden P; Jaspers H; Tóth G; Péter A; Kertész I; Török G; Chung NN; Schiller PW
    J Med Chem; 1998 Dec; 41(26):5167-76. PubMed ID: 9857087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The selectivity of the opioid antagonist, naltrindole, for delta-opioid receptors.
    Rogers H; Hayes AG; Birch PJ; Traynor JR; Lawrence AJ
    J Pharm Pharmacol; 1990 May; 42(5):358-9. PubMed ID: 1976787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
    Salvadori S; Balboni G; Guerrini R; Tomatis R; Bianchi C; Bryant SD; Cooper PS; Lazarus LH
    J Med Chem; 1997 Sep; 40(19):3100-8. PubMed ID: 9301674
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel ligands for the opioid receptors: synthesis and structure-activity relationships among 5'-aryl and 5'-heteroaryl 17-cyclopropylmethyl-4,5 alpha-epoxypyrido[2',3':6,7]morphinans.
    Ananthan S; Khare NK; Saini SK; Davis P; Dersch CM; Porreca F; Rothman RB
    Bioorg Med Chem; 2003 Sep; 11(18):4143-54. PubMed ID: 12927876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.