These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 9689499)

  • 1. C16 and C17 derivatives of estradiol as inhibitors of 17 beta-hydroxysteroid dehydrogenase type 1: chemical synthesis and structure-activity relationships.
    Sam KM; Boivin RP; Tremblay MR; Auger S; Poirier D
    Drug Des Discov; 1998 May; 15(3):157-80. PubMed ID: 9689499
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of type 2 17beta-hydroxysteroid dehydrogenase by estradiol derivatives bearing a lactone on the D-ring: structure-activity relationships.
    Bydal P; Auger S; Poirier D
    Steroids; 2004 May; 69(5):325-42. PubMed ID: 15219411
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone.
    Möller G; Deluca D; Gege C; Rosinus A; Kowalik D; Peters O; Droescher P; Elger W; Adamski J; Hillisch A
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6740-4. PubMed ID: 19836949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone.
    Laplante Y; Cadot C; Fournier MA; Poirier D
    Bioorg Med Chem; 2008 Feb; 16(4):1849-60. PubMed ID: 18035543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. C6-(N,N-butyl-methyl-heptanamide) derivatives of estrone and estradiol as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Chemical synthesis and biological evaluation.
    Cadot C; Laplante Y; Kamal F; Luu-The V; Poirier D
    Bioorg Med Chem; 2007 Jan; 15(2):714-26. PubMed ID: 17110114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of 16-(bromoalkyl)-estradiols having inhibitory effect on human placental estradiol 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD type 1).
    Tremblay MR; Auger S; Poirier D
    Bioorg Med Chem; 1995 May; 3(5):505-23. PubMed ID: 7648200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Estradiol-adenosine hybrid compounds designed to inhibit type 1 17beta-hydroxysteroid dehydrogenase.
    Poirier D; Boivin RP; Tremblay MR; Bérubé M; Qiu W; Lin SX
    J Med Chem; 2005 Dec; 48(26):8134-47. PubMed ID: 16366595
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overview of a rational approach to design type I 17beta-hydroxysteroid dehydrogenase inhibitors without estrogenic activity: chemical synthesis and biological evaluation.
    Tremblay MR; Poirier D
    J Steroid Biochem Mol Biol; 1998 Aug; 66(4):179-91. PubMed ID: 9744515
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
    Allan GM; Lawrence HR; Cornet J; Bubert C; Fischer DS; Vicker N; Smith A; Tutill HJ; Purohit A; Day JM; Mahon MF; Reed MJ; Potter BV
    J Med Chem; 2006 Feb; 49(4):1325-45. PubMed ID: 16480268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of simplified hybrid inhibitors of type 1 17beta-hydroxysteroid dehydrogenase via cross-metathesis and sonogashira coupling Reactions.
    Bérubé M; Poirier D
    Org Lett; 2004 Sep; 6(18):3127-30. PubMed ID: 15330604
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Estrone and estradiol C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase.
    Poirier D; Chang HJ; Azzi A; Boivin RP; Lin SX
    Mol Cell Endocrinol; 2006 Mar; 248(1-2):236-8. PubMed ID: 16337735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors.
    Laplante Y; Rancourt C; Poirier D
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):146-53. PubMed ID: 18812208
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and evaluation of estradiol derivatives with 16 alpha-(bromoalkylamide), 16 alpha-(bromoalkyl) or 16 alpha-(bromoalkynyl) side chain as inhibitors of 17 beta-hydroxysteroid dehydrogenase type 1 without estrogenic activity.
    Pelletier JD; Poirier D
    Bioorg Med Chem; 1996 Oct; 4(10):1617-28. PubMed ID: 8931931
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
    Vicker N; Lawrence HR; Allan GM; Bubert C; Smith A; Tutill HJ; Purohit A; Day JM; Mahon MF; Reed MJ; Potter BV
    ChemMedChem; 2006 Apr; 1(4):464-81. PubMed ID: 16892382
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors.
    Numazawa M; Kamiyama T; Tachibana M; Oshibe M
    J Med Chem; 1996 May; 39(11):2245-52. PubMed ID: 8667367
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxidations of 17beta-estradiol and estrone and their interconversions catalyzed by liver, mammary gland and mammary tumor after acute and chronic treatment of rats with indole-3-carbinol or beta-naphthoflavone.
    Ritter CL; Prigge WF; Reichert MA; Malejka-Giganti D
    Can J Physiol Pharmacol; 2001 Jun; 79(6):519-32. PubMed ID: 11430590
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dydrogesterone (Duphaston) and its 20-dihydro-derivative as selective estrogen enzyme modulators in human breast cancer cell lines. Effect on sulfatase and on 17beta-hydroxysteroid dehydrogenase (17beta-HSD) activity.
    Chetrite GS; Thole HH; Philippe JC; Pasqualini JR
    Anticancer Res; 2004; 24(3a):1433-8. PubMed ID: 15274306
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A 6beta-(thiaheptanamide) derivative of estradiol as inhibitor of 17beta-hydroxysteroid dehydrogenase type 1.
    Poirier D; Dionne P; Auger S
    J Steroid Biochem Mol Biol; 1998 Jan; 64(1-2):83-90. PubMed ID: 9569013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemical synthesis of 16beta-propylaminoacyl derivatives of estradiol and their inhibitory potency on type 1 17beta-hydroxysteroid dehydrogenase and binding affinity on steroid receptors.
    Tremblay MR; Lin SX; Poirier D
    Steroids; 2001 Nov; 66(11):821-31. PubMed ID: 11576622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD-II) activity in human placenta: its relationship to placental weight and birth weight and its possible role in hypertension.
    Hofmann M; Pollow K; Bahlmann F; Casper F; Steiner E; Brockerhoff P
    J Perinat Med; 2001; 29(1):23-30. PubMed ID: 11234613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.