263 related articles for article (PubMed ID: 9694074)
1. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.
Mareya SM; Sorrentino BP; Blakley RL
Cancer Gene Ther; 1998; 5(4):225-35. PubMed ID: 9694074
[TBL] [Abstract][Full Text] [Related]
2. Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells.
Allay JA; Galipeau J; Blakley RL; Sorrentino BP
Stem Cells; 1998; 16 Suppl 1():223-33. PubMed ID: 11012166
[TBL] [Abstract][Full Text] [Related]
3. Retroviral coexpression of thymidylate synthase and dihydrofolate reductase confers fluoropyrimidine and antifolate resistance.
Fantz CR; Shaw D; Moore JG; Spencer HT
Biochem Biophys Res Commun; 1998 Feb; 243(1):6-12. PubMed ID: 9473470
[TBL] [Abstract][Full Text] [Related]
4. Increased resistance to nitrogen mustards and antifolates following in vitro selection of murine fibroblasts and primary hematopoietic cells transduced with a bicistronic retroviral vector expressing the rat glutathione S-transferase A3 and a mutant dihydrofolate reductase.
Belzile JP; Karatzas A; Shiu HY; Létourneau S; Palerme JS; Cournoyer D
Cancer Gene Ther; 2003 Aug; 10(8):637-46. PubMed ID: 12872145
[TBL] [Abstract][Full Text] [Related]
5. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
McIvor RS
Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
[TBL] [Abstract][Full Text] [Related]
6. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Diddens H; Niethammer D; Jackson RC
Cancer Res; 1983 Nov; 43(11):5286-92. PubMed ID: 6225514
[TBL] [Abstract][Full Text] [Related]
7. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.
Takebe N; Zhao SC; Adhikari D; Mineishi S; Sadelain M; Hilton J; Colvin M; Banerjee D; Bertino JR
Mol Ther; 2001 Jan; 3(1):88-96. PubMed ID: 11162315
[TBL] [Abstract][Full Text] [Related]
8. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
[TBL] [Abstract][Full Text] [Related]
9. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.
Vinh DB; McIvor RS
J Pharmacol Exp Ther; 1993 Nov; 267(2):989-96. PubMed ID: 8246174
[TBL] [Abstract][Full Text] [Related]
10. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
Mayer-Kuckuk P; Banerjee D; Malhotra S; Doubrovin M; Iwamoto M; Akhurst T; Balatoni J; Bornmann W; Finn R; Larson S; Fong Y; Gelovani Tjuvajev J; Blasberg R; Bertino JR
Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3400-5. PubMed ID: 11891321
[TBL] [Abstract][Full Text] [Related]
11. Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.
James RI; May C; Vagt MD; Studebaker R; McIvor RS
Exp Hematol; 1997 Nov; 25(12):1286-95. PubMed ID: 9357973
[TBL] [Abstract][Full Text] [Related]
12. In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.
Blakley RL; Sorrentino BP
Hum Mutat; 1998; 11(4):259-63. PubMed ID: 9554740
[TBL] [Abstract][Full Text] [Related]
13. Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
Capiaux GM; Budak-Alpdogan T; Alpdogan O; Bornmann W; Takebe N; Banerjee D; Maley F; Bertino JR
Cancer Gene Ther; 2004 Dec; 11(12):767-73. PubMed ID: 15359285
[TBL] [Abstract][Full Text] [Related]
14. Molecular mechanisms of resistance to antifolates, a review.
Banerjee D; Ercikan-Abali E; Waltham M; Schnieders B; Hochhauser D; Li WW; Fan J; Gorlick R; Goker E; Bertino JR
Acta Biochim Pol; 1995; 42(4):457-64. PubMed ID: 8852336
[TBL] [Abstract][Full Text] [Related]
15. Cancer research: from folate antagonism to molecular targets.
Bertino JR
Best Pract Res Clin Haematol; 2009 Dec; 22(4):577-82. PubMed ID: 19959110
[TBL] [Abstract][Full Text] [Related]
16. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.
Affleck JG; Nowickyj SM; Walker VK
Cell Biol Toxicol; 2010 Apr; 26(2):117-26. PubMed ID: 19337845
[TBL] [Abstract][Full Text] [Related]
17. Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants.
Patel M; Sleep SE; Lewis WS; Spencer HT; Mareya SM; Sorrentino BP; Blakley RL
Hum Gene Ther; 1997 Nov; 8(17):2069-77. PubMed ID: 9414255
[TBL] [Abstract][Full Text] [Related]
18. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
Takebe N; Xu LC; MacKenzie KL; Bertino JR; Moore MA
Cancer Gene Ther; 2002 Mar; 9(3):308-20. PubMed ID: 11896448
[TBL] [Abstract][Full Text] [Related]
19. Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors.
Takebe N; Nakahara S; Zhao SC; Adhikari D; Ural AU; Iwamoto M; Banerjee D; Bertino JR
Cancer Gene Ther; 2000 Jun; 7(6):910-9. PubMed ID: 10880023
[TBL] [Abstract][Full Text] [Related]
20. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate.
Fanin R; Banerjee D; Volkenandt M; Waltham M; Li WW; Dicker AP; Schweitzer BI; Bertino JR
Mol Pharmacol; 1993 Jul; 44(1):13-21. PubMed ID: 8341268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
