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7. SHP-2 binds to Tyr763 and Tyr1009 in the PDGF beta-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis. Rönnstrand L; Arvidsson AK; Kallin A; Rorsman C; Hellman U; Engström U; Wernstedt C; Heldin CH Oncogene; 1999 Jun; 18(25):3696-702. PubMed ID: 10391677 [TBL] [Abstract][Full Text] [Related]
8. The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases. Shi ZQ; Lu W; Feng GS J Biol Chem; 1998 Feb; 273(9):4904-8. PubMed ID: 9478933 [TBL] [Abstract][Full Text] [Related]
9. Shp-2 has a positive regulatory role in ES cell differentiation and proliferation. Qu CK; Feng GS Oncogene; 1998 Jul; 17(4):433-9. PubMed ID: 9696036 [TBL] [Abstract][Full Text] [Related]
10. Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2. Saxton TM; Henkemeyer M; Gasca S; Shen R; Rossi DJ; Shalaby F; Feng GS; Pawson T EMBO J; 1997 May; 16(9):2352-64. PubMed ID: 9171349 [TBL] [Abstract][Full Text] [Related]
11. Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins. Yokote K; Hellman U; Ekman S; Saito Y; Rönnstrand L; Saito Y; Heldin CH; Mori S Oncogene; 1998 Mar; 16(10):1229-39. PubMed ID: 9546424 [TBL] [Abstract][Full Text] [Related]
12. Localization and down-regulating role of the protein tyrosine phosphatase PTP2C in membrane ruffles of PDGF-stimulated cells. Cossette LJ; Hoglinger O; Mou L; Shen SH Exp Cell Res; 1996 Mar; 223(2):459-66. PubMed ID: 8601424 [TBL] [Abstract][Full Text] [Related]
13. Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation. Bazenet CE; Gelderloos JA; Kazlauskas A Mol Cell Biol; 1996 Dec; 16(12):6926-36. PubMed ID: 8943348 [TBL] [Abstract][Full Text] [Related]
14. SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis. Ivins Zito C; Kontaridis MI; Fornaro M; Feng GS; Bennett AM J Cell Physiol; 2004 May; 199(2):227-36. PubMed ID: 15040005 [TBL] [Abstract][Full Text] [Related]
15. Transforming growth factor beta 1 downregulates the platelet-derived growth factor alpha-receptor subtype on human lung fibroblasts in vitro. Bonner JC; Badgett A; Lindroos PM; Osornio-Vargas AR Am J Respir Cell Mol Biol; 1995 Oct; 13(4):496-505. PubMed ID: 7546780 [TBL] [Abstract][Full Text] [Related]
17. Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584. Vogel W; Ullrich A Cell Growth Differ; 1996 Dec; 7(12):1589-97. PubMed ID: 8959326 [TBL] [Abstract][Full Text] [Related]
18. Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. You M; Yu DH; Feng GS Mol Cell Biol; 1999 Mar; 19(3):2416-24. PubMed ID: 10022928 [TBL] [Abstract][Full Text] [Related]
19. The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with rasGAP. Bazenet CE; Kazlauskas A Oncogene; 1994 Feb; 9(2):517-25. PubMed ID: 8290262 [TBL] [Abstract][Full Text] [Related]
20. Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src. Schlesinger TK; Demali KA; Johnson GL; Kazlauskas A Biochem J; 1999 Dec; 344 Pt 2(Pt 2):519-26. PubMed ID: 10567236 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]