BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 9697843)

  • 1. Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting.
    Rada C; Ehrenstein MR; Neuberger MS; Milstein C
    Immunity; 1998 Jul; 9(1):135-41. PubMed ID: 9697843
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications.
    Kim N; Bozek G; Lo JC; Storb U
    J Exp Med; 1999 Jul; 190(1):21-30. PubMed ID: 10429667
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process.
    Frey S; Bertocci B; Delbos F; Quint L; Weill JC; Reynaud CA
    Immunity; 1998 Jul; 9(1):127-34. PubMed ID: 9697842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.
    Alabyev B; Manser T
    J Immunol; 2002 Oct; 169(7):3819-24. PubMed ID: 12244177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.
    Ehrenstein MR; Neuberger MS
    EMBO J; 1999 Jun; 18(12):3484-90. PubMed ID: 10369687
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination.
    Martin A; Li Z; Lin DP; Bardwell PD; Iglesias-Ussel MD; Edelmann W; Scharff MD
    J Exp Med; 2003 Oct; 198(8):1171-8. PubMed ID: 14568978
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein.
    Phung QH; Winter DB; Cranston A; Tarone RE; Bohr VA; Fishel R; Gearhart PJ
    J Exp Med; 1998 Jun; 187(11):1745-51. PubMed ID: 9607916
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern.
    Wiesendanger M; Kneitz B; Edelmann W; Scharff MD
    J Exp Med; 2000 Feb; 191(3):579-84. PubMed ID: 10662804
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of bcl-2 alters usage of mutational hot spots in germinal center B cells.
    Kuo P; Alban A; Gebhard D; Diamond B
    Mol Immunol; 1997 Oct; 34(14):1011-8. PubMed ID: 9488052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
    Chezar I; Lobel-Lavi L; Steinitz M; Laskov R
    Mol Immunol; 2008 Nov; 46(1):80-90. PubMed ID: 18718665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Severe attenuation of the B cell immune response in Msh2-deficient mice.
    Vora KA; Tumas-Brundage KM; Lentz VM; Cranston A; Fishel R; Manser T
    J Exp Med; 1999 Feb; 189(3):471-82. PubMed ID: 9927509
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts.
    Andrew SE; Xu XS; Baross-Francis A; Narayanan L; Milhausen K; Liskay RM; Jirik FR; Glazer PM
    Carcinogenesis; 2000 Jul; 21(7):1291-5. PubMed ID: 10874005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Msh2 deficiency increases the mutation frequency in all parts of the mouse colon.
    Zhang S; Lloyd R; Bowden G; Glickman BW; de Boer JG
    Environ Mol Mutagen; 2002; 40(4):243-50. PubMed ID: 12489114
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Msh2 deficiency enhances somatic Apc and p53 mutations in Apc+/-Msh2-/- mice.
    Sohn KJ; Choi M; Song J; Chan S; Medline A; Gallinger S; Kim YI
    Carcinogenesis; 2003 Feb; 24(2):217-24. PubMed ID: 12584170
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation.
    Rada C; Di Noia JM; Neuberger MS
    Mol Cell; 2004 Oct; 16(2):163-71. PubMed ID: 15494304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Msh2 DNA mismatch repair gene deficiency and the food-borne mutagen 2-amino-1-methy1-6-phenolimidazo [4,5-b] pyridine (PhIP) synergistically affect mutagenesis in mouse colon.
    Zhang S; Lloyd R; Bowden G; Glickman BW; de Boer JG
    Oncogene; 2001 Sep; 20(42):6066-72. PubMed ID: 11593414
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine.
    Berry SE; Davis TW; Schupp JE; Hwang HS; de Wind N; Kinsella TJ
    Cancer Res; 2000 Oct; 60(20):5773-80. PubMed ID: 11059773
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice.
    Yang X; Stedra J; Cerny J
    J Exp Med; 1996 Mar; 183(3):959-70. PubMed ID: 8642299
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.
    Cui A; Di Niro R; Vander Heiden JA; Briggs AW; Adams K; Gilbert T; O'Connor KC; Vigneault F; Shlomchik MJ; Kleinstein SH
    J Immunol; 2016 Nov; 197(9):3566-3574. PubMed ID: 27707999
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrum.
    Zhang S; Lloyd R; Bowden G; Glickman BW; de Boer JG
    Mutat Res; 2002 Mar; 500(1-2):67-74. PubMed ID: 11890935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.