These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 9703471)

  • 1. 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase.
    Perry PJ; Gowan SM; Reszka AP; Polucci P; Jenkins TC; Kelland LR; Neidle S
    J Med Chem; 1998 Aug; 41(17):3253-60. PubMed ID: 9703471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones.
    Perry PJ; Reszka AP; Wood AA; Read MA; Gowan SM; Dosanjh HS; Trent JO; Jenkins TC; Kelland LR; Neidle S
    J Med Chem; 1998 Nov; 41(24):4873-84. PubMed ID: 9822556
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone.
    Huang HS; Chiou JF; Fong Y; Hou CC; Lu YC; Wang JY; Shih JW; Pan YR; Lin JJ
    J Med Chem; 2003 Jul; 46(15):3300-7. PubMed ID: 12852760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones.
    Huang HS; Chou CL; Guo CL; Yuan CL; Lu YC; Shieh FY; Lin JJ
    Bioorg Med Chem; 2005 Mar; 13(5):1435-44. PubMed ID: 15698759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase.
    Perry PJ; Read MA; Davies RT; Gowan SM; Reszka AP; Wood AA; Kelland LR; Neidle S
    J Med Chem; 1999 Jul; 42(14):2679-84. PubMed ID: 10411488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity correlations of the cytotoxic bifunctional 1,4-diamidoanthraquinone derivatives.
    Huang HS; Chiu HF; Lee AL; Guo CL; Yuan CL
    Bioorg Med Chem; 2004 Dec; 12(23):6163-70. PubMed ID: 15519160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives.
    Huang HS; Huang KF; Li CL; Huang YY; Chiang YH; Huang FC; Lin JJ
    Bioorg Med Chem; 2008 Jul; 16(14):6976-86. PubMed ID: 18571928
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tri-, tetra- and heptacyclic perylene analogues as new potential antineoplastic agents based on DNA telomerase inhibition.
    Sissi C; Lucatello L; Paul Krapcho A; Maloney DJ; Boxer MB; Camarasa MV; Pezzoni G; Menta E; Palumbo M
    Bioorg Med Chem; 2007 Jan; 15(1):555-62. PubMed ID: 17035038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NSC746364, NSC746365, and NSC746366: the spectra of cytotoxicity and molecular correlates of response to telomerase activity.
    Huang HS; Huang KF; Lee CC; Chen CL; Li CL; Lin JJ
    Anticancer Drugs; 2010 Feb; 21(2):169-80. PubMed ID: 19884821
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular modeling studies on G-quadruplex complexes of telomerase inhibitors: structure-activity relationships.
    Read MA; Wood AA; Harrison JR; Gowan SM; Kelland LR; Dosanjh HS; Neidle S
    J Med Chem; 1999 Nov; 42(22):4538-46. PubMed ID: 10579817
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology.
    Chen CL; Chang DM; Chen TC; Lee CC; Hsieh HH; Huang FC; Huang KF; Guh JH; Lin JJ; Huang HS
    Eur J Med Chem; 2013 Feb; 60():29-41. PubMed ID: 23279865
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivatives.
    Lee CC; Huang KF; Lin PY; Huang FC; Chen CL; Chen TC; Guh JH; Lin JJ; Huang HS
    Eur J Med Chem; 2012 Jan; 47(1):323-36. PubMed ID: 22100139
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of human telomerase by a G-quadruplex-interactive compound.
    Sun D; Thompson B; Cathers BE; Salazar M; Kerwin SM; Trent JO; Jenkins TC; Neidle S; Hurley LH
    J Med Chem; 1997 Jul; 40(14):2113-6. PubMed ID: 9216827
    [No Abstract]   [Full Text] [Related]  

  • 14. Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro.
    Hayakawa N; Nozawa K; Ogawa A; Kato N; Yoshida K; Akamatsu Ki; Tsuchiya M; Nagasaka A; Yoshida S
    Biochemistry; 1999 Aug; 38(35):11501-7. PubMed ID: 10471302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular modelling and cytotoxicity of substituted anthraquinones as inhibitors of human telomerase.
    Cairns D; Michalitsi E; Jenkins TC; Mackay SP
    Bioorg Med Chem; 2002 Mar; 10(3):803-7. PubMed ID: 11814869
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,11-dione homologues.
    Huang HS; Chen TC; Chen RH; Huang KF; Huang FC; Jhan JR; Chen CL; Lee CC; Lo Y; Lin JJ
    Bioorg Med Chem; 2009 Nov; 17(21):7418-28. PubMed ID: 19804981
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aminoacyl-anthraquinone conjugates as telomerase inhibitors: synthesis, biophysical and biological evaluation.
    Zagotto G; Sissi C; Lucatello L; Pivetta C; Cadamuro SA; Fox KR; Neidle S; Palumbo M
    J Med Chem; 2008 Sep; 51(18):5566-74. PubMed ID: 18754611
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors.
    Read M; Harrison RJ; Romagnoli B; Tanious FA; Gowan SH; Reszka AP; Wilson WD; Kelland LR; Neidle S
    Proc Natl Acad Sci U S A; 2001 Apr; 98(9):4844-9. PubMed ID: 11309493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
    Izbicka E; Wheelhouse RT; Raymond E; Davidson KK; Lawrence RA; Sun D; Windle BE; Hurley LH; Von Hoff DD
    Cancer Res; 1999 Feb; 59(3):639-44. PubMed ID: 9973212
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oligonucleotide N3'-->P5' phosphoramidates as efficient telomerase inhibitors.
    Herbert BS; Pongracz K; Shay JW; Gryaznov SM
    Oncogene; 2002 Jan; 21(4):638-42. PubMed ID: 11850790
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.