152 related articles for article (PubMed ID: 9703475)
1. Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents.
Reddy NL; Fan W; Magar SS; Perlman ME; Yost E; Zhang L; Berlove D; Fischer JB; Burke-Howie K; Wolcott T; Durant GJ
J Med Chem; 1998 Aug; 41(17):3298-302. PubMed ID: 9703475
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels.
Maillard MC; Perlman ME; Amitay O; Baxter D; Berlove D; Connaughton S; Fischer JB; Guo JQ; Hu LY; McBurney RN; Nagy PI; Subbarao K; Yost EA; Zhang L; Durant GJ
J Med Chem; 1998 Jul; 41(16):3048-61. PubMed ID: 9685245
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and anticonvulsant activity of a class of 2-amino 3-hydroxypropanamide and 2-aminoacetamide derivatives.
Ghidini E; Delcanale M; De Fanti R; Rizzi A; Mazzuferi M; Rodi D; Simonato M; Lipreri M; Bassani F; Battipaglia L; Bergamaschi M; Villetti G
Bioorg Med Chem; 2006 May; 14(10):3263-74. PubMed ID: 16460950
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and anticonvulsant evaluation of N-substituted isoquinoline AMPA receptor antagonists.
Gitto R; De Luca L; Pagano B; Citraro R; De Sarro G; Costa L; Ciranna L; Chimirri A
Bioorg Med Chem; 2008 Mar; 16(5):2379-84. PubMed ID: 18077172
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, anticonvulsant activity, and structure-activity relationships of sodium channel blocking 3-aminopyrroles.
Unverferth K; Engel J; Höfgen N; Rostock A; Günther R; Lankau HJ; Menzer M; Rolfs A; Liebscher J; Müller B; Hofmann HJ
J Med Chem; 1998 Jan; 41(1):63-73. PubMed ID: 9438023
[TBL] [Abstract][Full Text] [Related]
6. Solution-phase parallel synthesis and evaluation of anticonvulsant activity of N-substituted-3,4-dihydroisoquinoline-2(1H)-carboxamides.
Gitto R; Pagano B; Citraro R; Scicchitano F; De Sarro G; Chimirri A
Eur J Med Chem; 2009 Mar; 44(3):1349-54. PubMed ID: 18406016
[TBL] [Abstract][Full Text] [Related]
7. Anticonvulsant activity and interactions with neuronal voltage-dependent sodium channel of analogues of ameltolide.
Vamecq J; Lambert D; Poupaert JH; Masereel B; Stables JP
J Med Chem; 1998 Aug; 41(18):3307-13. PubMed ID: 9719582
[TBL] [Abstract][Full Text] [Related]
8. A structure-activity relationship study of novel phenylacetamides which are sodium channel blockers.
Roufos I; Hays S; Schwarz RD
J Med Chem; 1996 Mar; 39(7):1514-20. PubMed ID: 8691482
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.
Gitto R; Ferro S; Agnello S; De Luca L; De Sarro G; Russo E; Vullo D; Supuran CT; Chimirri A
Bioorg Med Chem; 2009 May; 17(10):3659-64. PubMed ID: 19398204
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist.
Reddy NL; Hu LY; Cotter RE; Fischer JB; Wong WJ; McBurney RN; Weber E; Holmes DL; Wong ST; Prasad R
J Med Chem; 1994 Jan; 37(2):260-7. PubMed ID: 8295213
[TBL] [Abstract][Full Text] [Related]
11. Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.
Benes J; Parada A; Figueiredo AA; Alves PC; Freitas AP; Learmonth DA; Cunha RA; Garrett J; Soares-da-Silva P
J Med Chem; 1999 Jul; 42(14):2582-7. PubMed ID: 10411478
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and potential anticonvulsant activity of new N-3-substituted 5,5-cyclopropanespirohydantoins.
Zhu Q; Pan Y; Xu Z; Li R; Qiu G; Xu W; Ke X; Wu L; Hu X
Eur J Med Chem; 2009 Jan; 44(1):296-302. PubMed ID: 18396358
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, physicochemical properties, anticonvulsant activities and voltage-sensitive calcium channels affinity of N-substituted amides of alpha-(4-phenylpiperazino)-GABA. Part 3: Search for new anticonvulsant compounds.
Malawska B; Antkiewicz-Michaluk L
Pharmazie; 1999 Apr; 54(4):239-43. PubMed ID: 10234733
[TBL] [Abstract][Full Text] [Related]
14. Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton.
Gitto R; Caruso R; Pagano B; De Luca L; Citraro R; Russo E; De Sarro G; Chimirri A
J Med Chem; 2006 Sep; 49(18):5618-22. PubMed ID: 16942035
[TBL] [Abstract][Full Text] [Related]
15. 3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: a new class of AMPA receptor antagonists.
Chimirri A; De Sarro G; De Sarro A; Gitto R; Quartarone S; Zappalà M; Constanti A; Libri V
J Med Chem; 1998 Aug; 41(18):3409-16. PubMed ID: 9719593
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones.
Patel HJ; Sarra J; Caruso F; Rossi M; Doshi U; Stephani RA
Bioorg Med Chem Lett; 2006 Sep; 16(17):4644-7. PubMed ID: 16793262
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of thio-containing compounds with serum HDL-cholesterol-elevating properties.
Elokdah H; Sulkowski TS; Abou-Gharbia M; Butera JA; Chai SY; McFarlane GR; McKean ML; Babiak JL; Adelman SJ; Quinet EM
J Med Chem; 2004 Jan; 47(3):681-95. PubMed ID: 14736248
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of new N-substituted-N'-(3,5-di/1,3,5-trimethylpyrazole-4-yl)thiourea/urea derivatives.
Kaymakçioğlu BK; Rollas S; Körceğez E; Aricioğlu F
Eur J Pharm Sci; 2005 Sep; 26(1):97-103. PubMed ID: 15990284
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and anticonvulsant activity of 4-(2-(2,6-dimethylphenylamino)-2-oxoethylamino)-N-(substituted)butanamides: a pharmacophoric hybrid approach.
Yogeeswari P; Sriram D; Sahitya P; Ragavendran JV; Ranganadh V
Bioorg Med Chem Lett; 2007 Jul; 17(13):3712-5. PubMed ID: 17481896
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and structure activity relationship of guanidines as NPY Y5 antagonists.
Aquino CJ; Ramanjulu JM; Heyer D; Daniels AJ; Palazzo F; Dezube M
Bioorg Med Chem; 2004 May; 12(10):2691-708. PubMed ID: 15110851
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
