These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 9705520)

  • 1. 4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase.
    Marx A; Amacker M; Stucki M; Hübscher U; Bickle TA; Giese B
    Nucleic Acids Res; 1998 Sep; 26(17):4063-7. PubMed ID: 9705520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases γ and β by thiated 3'-fluorothymidine analogue 5'-triphosphates.
    Wińska P; Miazga A; Poznański J; Kulikowski T
    Antiviral Res; 2010 Nov; 88(2):176-81. PubMed ID: 20739003
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
    Maga G; Amacker M; Hübscher U; Gosselin G; Imbach JL; Mathé C; Faraj A; Sommadossi JP; Spadari S
    Nucleic Acids Res; 1999 Feb; 27(4):972-8. PubMed ID: 9927728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of inhibition of the human immunodeficiency virus type 1 reverse transcriptase by d4TTP: an equivalent incorporation efficiency relative to the natural substrate dTTP.
    Vaccaro JA; Parnell KM; Terezakis SA; Anderson KS
    Antimicrob Agents Chemother; 2000 Jan; 44(1):217-21. PubMed ID: 10602755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 5'-triphosphate mimics (P3Ms) of 3'-azido-3',5'-dideoxythymidine and 3',5'-dideoxy-5'-difluoromethylenethymidine as HIV-1 reverse transcriptase inhibitors.
    Rajwanshi VK; Prhavc M; Fagan P; Brooks JL; Hurd T; Cook PD; Wang G
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(3):179-89. PubMed ID: 15892257
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate.
    Focher F; Maga G; Bendiscioli A; Capobianco M; Colonna F; Garbesi A; Spadari S
    Nucleic Acids Res; 1995 Aug; 23(15):2840-7. PubMed ID: 7544886
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
    Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
    Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanistic studies to understand the inhibition of wild type and mutant HIV-1 reverse transcriptase by Carbovir-triphosphate.
    Ray AS; Anderson KS
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):1247-50. PubMed ID: 11562995
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP; Nandy P; Avramis VI
    In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biochemical studies on the mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to 1-(beta-D-dioxolane)thymine triphosphate.
    Lennerstrand J; Chu CK; Schinazi RF
    Antimicrob Agents Chemother; 2007 Jun; 51(6):2078-84. PubMed ID: 17403997
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synergistic inhibition of HIV-1 reverse transcriptase by combinations of chain-terminating nucleotides.
    Villahermosa ML; Martinez-Irujo JJ; Cabodevilla F; Santiago E
    Biochemistry; 1997 Oct; 36(43):13223-31. PubMed ID: 9341211
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT.
    Yang G; Dutschman GE; Wang CJ; Tanaka H; Baba M; Anderson KS; Cheng YC
    Antiviral Res; 2007 Mar; 73(3):185-91. PubMed ID: 17109975
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibitory effects of 2'-deoxy-L-thymidine 5'-triphosphate on human immunodeficiency virus reverse transcriptase and eukaryotic DNA polymerases.
    Yamaguchi T; Saneyoshi M; Shudo K
    Nucleic Acids Symp Ser; 1993; (29):135-6. PubMed ID: 7504240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pronounced Inhibition Shift from HIV Reverse Transcriptase to Herpetic DNA Polymerases by Increasing the Flexibility of α-Carboxy Nucleoside Phosphonates.
    John J; Kim Y; Bennett N; Das K; Liekens S; Naesens L; Arnold E; Maguire AR; Götte M; Dehaen W; Balzarini J
    J Med Chem; 2015 Oct; 58(20):8110-27. PubMed ID: 26450273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chiral discrimination of enantiomeric 2'-deoxythymidine 5'-triphosphate by HIV-1 reverse transcriptase and eukaryotic DNA polymerases.
    Yamaguchi T; Iwanami N; Shudo K; Saneyoshi M
    Biochem Biophys Res Commun; 1994 Apr; 200(2):1023-7. PubMed ID: 7513992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.
    Menéndez-Arias L
    Virus Res; 2008 Jun; 134(1-2):124-46. PubMed ID: 18272247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
    Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of viral polymerases by chain-terminating substrates: a kinetic analysis.
    Wilson JE; Porter DJ; Reardon JE
    Methods Enzymol; 1996; 275():398-424. PubMed ID: 9026652
    [No Abstract]   [Full Text] [Related]  

  • 19. Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.
    von Janta-Lipinski M; Costisella B; Ochs H; Hübscher U; Hafkemeyer P; Matthes E
    J Med Chem; 1998 Jun; 41(12):2040-6. PubMed ID: 9622545
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of action of (-)-(2R,4R)-1-(2-hydroxymethyl-1,3-dioxolan-4-yl) thymine as an anti-HIV agent.
    Murakami E; Bao H; Basavapathruni A; Bailey CM; Du J; Steuer HM; Niu C; Whitaker T; Anderson KS; Otto MJ; Furman PA
    Antivir Chem Chemother; 2007; 18(2):83-92. PubMed ID: 17542153
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.