These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 9716710)

  • 1. Effects of temperature and mexiletine on the F1473S Na+ channel mutation causing paramyotonia congenita.
    Fleischhauer R; Mitrovic N; Deymeer F; Lehmann-Horn F; Lerche H
    Pflugers Arch; 1998 Oct; 436(5):757-65. PubMed ID: 9716710
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A1152D mutation of the Na+ channel causes paramyotonia congenita and emphasizes the role of DIII/S4-S5 linker in fast inactivation.
    Bouhours M; Luce S; Sternberg D; Willer JC; Fontaine B; Tabti N
    J Physiol; 2005 Jun; 565(Pt 2):415-27. PubMed ID: 15790667
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians.
    Zhao J; Duprè N; Puymirat J; Chahine M
    J Physiol; 2012 Jun; 590(11):2629-44. PubMed ID: 22250216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization and cold sensitivity of T1313A, a new mutation of the skeletal muscle sodium channel causing paramyotonia congenita in humans.
    Bouhours M; Sternberg D; Davoine CS; Ferrer X; Willer JC; Fontaine B; Tabti N
    J Physiol; 2004 Feb; 554(Pt 3):635-47. PubMed ID: 14617673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mexiletine block of disease-associated mutations in S6 segments of the human skeletal muscle Na(+) channel.
    Takahashi MP; Cannon SC
    J Physiol; 2001 Dec; 537(Pt 3):701-14. PubMed ID: 11744749
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different effects on gating of three myotonia-causing mutations in the inactivation gate of the human muscle sodium channel.
    Mitrović N; George AL; Lerche H; Wagner S; Fahlke C; Lehmann-Horn F
    J Physiol; 1995 Aug; 487(1):107-14. PubMed ID: 7473241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block.
    Desaphy JF; De Luca A; Didonna MP; George AL; Camerino Conte D
    J Physiol; 2004 Jan; 554(Pt 2):321-34. PubMed ID: 14608015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.
    Sasaki K; Makita N; Sunami A; Sakurada H; Shirai N; Yokoi H; Kimura A; Tohse N; Hiraoka M; Kitabatake A
    Mol Pharmacol; 2004 Aug; 66(2):330-6. PubMed ID: 15266024
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
    Wang GK; Russell C; Wang SY
    J Physiol; 2004 Feb; 554(Pt 3):621-33. PubMed ID: 14608007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gating of myotonic Na channel mutants defines the response to mexiletine and a potent derivative.
    Desaphy JF; De Luca A; Tortorella P; De Vito D; George AL; Conte Camerino D
    Neurology; 2001 Nov; 57(10):1849-57. PubMed ID: 11723275
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A C-terminal skeletal muscle sodium channel mutation associated with myotonia disrupts fast inactivation.
    Wu FF; Gordon E; Hoffman EP; Cannon SC
    J Physiol; 2005 Jun; 565(Pt 2):371-80. PubMed ID: 15774523
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effects of paramyotonia congenita mutations F1473S and F1705I on sodium channel gating.
    Groome JR; Larsen MF; Coonts A
    Channels (Austin); 2008; 2(1):39-50. PubMed ID: 18690054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The human skeletal muscle Na channel mutation R669H associated with hypokalemic periodic paralysis enhances slow inactivation.
    Struyk AF; Scoggan KA; Bulman DE; Cannon SC
    J Neurosci; 2000 Dec; 20(23):8610-7. PubMed ID: 11102465
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role in fast inactivation of conserved amino acids in the IV/S4-S5 loop of the human muscle Na+ channel.
    Mitrovic N; Lerche H; Heine R; Fleischhauer R; Pika-Hartlaub U; Hartlaub U; George AL; Lehmann-Horn F
    Neurosci Lett; 1996 Aug; 214(1):9-12. PubMed ID: 8873119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A human muscle Na+ channel mutation in the voltage sensor IV/S4 affects channel block by the pentapeptide KIFMK.
    Peter W; Mitrovic N; Schiebe M; Lehmann-Horn F; Lerche H
    J Physiol; 1999 Jul; 518(Pt 1):13-22. PubMed ID: 10373685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.
    Weckbecker K; Würz A; Mohammadi B; Mansuroglu T; George AL; Lerche H; Dengler R; Lehmann-Horn F; Mitrovic N
    Neuromuscul Disord; 2000 Jan; 10(1):31-9. PubMed ID: 10677861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of cold sensitivity of paramyotonia congenita mutation R1448H and overlap syndrome mutation M1360V.
    Mohammadi B; Mitrovic N; Lehmann-Horn F; Dengler R; Bufler J
    J Physiol; 2003 Mar; 547(Pt 3):691-8. PubMed ID: 12562902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3.
    Ruan Y; Denegri M; Liu N; Bachetti T; Seregni M; Morotti S; Severi S; Napolitano C; Priori SG
    Circ Res; 2010 Apr; 106(8):1374-83. PubMed ID: 20339117
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Class Ic antiarrhythmics block human skeletal muscle Na channel during myotonia-like stimulation.
    Aoike F; Takahashi MP; Sakoda S
    Eur J Pharmacol; 2006 Feb; 532(1-2):24-31. PubMed ID: 16473348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced slow inactivation by V445M: a sodium channel mutation associated with myotonia.
    Takahashi MP; Cannon SC
    Biophys J; 1999 Feb; 76(2):861-8. PubMed ID: 9929487
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.