These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 9721209)

  • 1. Characterization of the human dihydropyrimidine dehydrogenase gene.
    Wei X; Elizondo G; Sapone A; McLeod HL; Raunio H; Fernandez-Salguero P; Gonzalez FJ
    Genomics; 1998 Aug; 51(3):391-400. PubMed ID: 9721209
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural organization of the human dihydropyrimidine dehydrogenase gene.
    Johnson MR; Wang K; Tillmanns S; Albin N; Diasio RB
    Cancer Res; 1997 May; 57(9):1660-3. PubMed ID: 9135003
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A high-throughput denaturing high-performance liquid chromatography method for the identification of variant alleles associated with dihydropyrimidine dehydrogenase deficiency.
    Ezzeldin H; Okamoto Y; Johnson MR; Diasio RB
    Anal Biochem; 2002 Jul; 306(1):63-73. PubMed ID: 12069415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype.
    Johnson MR; Wang K; Diasio RB
    Clin Cancer Res; 2002 Mar; 8(3):768-74. PubMed ID: 11895907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.
    van Kuilenburg AB; Haasjes J; Richel DJ; Zoetekouw L; Van Lenthe H; De Abreu RA; Maring JG; Vreken P; van Gennip AH
    Clin Cancer Res; 2000 Dec; 6(12):4705-12. PubMed ID: 11156223
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.
    Raida M; Schwabe W; Häusler P; Van Kuilenburg AB; Van Gennip AH; Behnke D; Höffken K
    Clin Cancer Res; 2001 Sep; 7(9):2832-9. PubMed ID: 11555601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Known variant DPYD alleles do not explain DPD deficiency in cancer patients.
    Collie-Duguid ES; Etienne MC; Milano G; McLeod HL
    Pharmacogenetics; 2000 Apr; 10(3):217-23. PubMed ID: 10803677
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diagnosis of dihydropyrimidine dehydrogenase deficiency in a neonate with thymine-uraciluria.
    Au KM; Lai CK; Yuen YP; Shek CC; Lam CW; Chan AY
    Hong Kong Med J; 2003 Apr; 9(2):130-2. PubMed ID: 12668826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of three novel mutations in the dihydropyrimidine dehydrogenase gene associated with altered pre-mRNA splicing or protein function.
    Van Kuilenburg AB; Meinsma R; Beke E; Bobba B; Boffi P; Enns GM; Witt DR; Dobritzsch D
    Biol Chem; 2005 Apr; 386(4):319-24. PubMed ID: 15899693
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency.
    van Kuilenburg AB; Muller EW; Haasjes J; Meinsma R; Zoetekouw L; Waterham HR; Baas F; Richel DJ; van Gennip AH
    Clin Cancer Res; 2001 May; 7(5):1149-53. PubMed ID: 11350878
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of a novel mutation in the dihydropyrimidine dehydrogenase gene in a patient with a lethal outcome following 5-fluorouracil administration and the determination of its frequency in a population of 500 patients with colorectal carcinoma.
    Morel A; Boisdron-Celle M; Fey L; Lainé-Cessac P; Gamelin E
    Clin Biochem; 2007 Jan; 40(1-2):11-7. PubMed ID: 17046731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutational analysis of the human dihydropyrimidine dehydrogenase gene by denaturing high-performance liquid chromatography.
    Fischer J; Schwab M; Eichelbaum M; Zanger UM
    Genet Test; 2003; 7(2):97-105. PubMed ID: 12885330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.
    Wei X; McLeod HL; McMurrough J; Gonzalez FJ; Fernandez-Salguero P
    J Clin Invest; 1996 Aug; 98(3):610-5. PubMed ID: 8698850
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutational spectrum of dihydropyrimidine dehydrogenase gene (DPYD) in the Tunisian population.
    Ben Fredj R; Gross E; Chouchen L; B'Chir F; Ben Ahmed S; Neubauer S; Kiechle M; Saguem S
    C R Biol; 2007 Oct; 330(10):764-9. PubMed ID: 17905396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lack of correlation between phenotype and genotype for the polymorphically expressed dihydropyrimidine dehydrogenase in a family of Pakistani origin.
    Fernandez-Salguero PM; Sapone A; Wei X; Holt JR; Jones S; Idle JR; Gonzalez FJ
    Pharmacogenetics; 1997 Apr; 7(2):161-3. PubMed ID: 9170156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FRA1E common fragile site breaks map within a 370kilobase pair region and disrupt the dihydropyrimidine dehydrogenase gene (DPYD).
    Hormozian F; Schmitt JG; Sagulenko E; Schwab M; Savelyeva L
    Cancer Lett; 2007 Feb; 246(1-2):82-91. PubMed ID: 16556484
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-throughput genotyping by DHPLC of the dihydropyrimidine dehydrogenase gene implicated in (fluoro)pyrimidine catabolism.
    Gross E; Seck K; Neubauer S; Mayr J; Hellebrand H; Ratanaphan A; Lutz V; Stockinger H; Kiechle M
    Int J Oncol; 2003 Feb; 22(2):325-32. PubMed ID: 12527930
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients.
    Ezzeldin HH; Lee AM; Mattison LK; Diasio RB
    Clin Cancer Res; 2005 Dec; 11(24 Pt 1):8699-705. PubMed ID: 16361556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cloning and initial characterization of the human DPYD gene promoter.
    Collie-Duguid ES; Johnston SJ; Powrie RH; Milano G; Etienne MC; Rochat B; Watson GC; McLeod HL
    Biochem Biophys Res Commun; 2000 Apr; 271(1):28-35. PubMed ID: 10777676
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea.
    Meinsma R; Fernandez-Salguero P; Van Kuilenburg AB; Van Gennip AH; Gonzalez FJ
    DNA Cell Biol; 1995 Jan; 14(1):1-6. PubMed ID: 7832988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.