BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 9722627)

  • 1. The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression.
    Smith MD; Dawson SJ; Boxer LM; Latchman DS
    Nucleic Acids Res; 1998 Sep; 26(18):4100-7. PubMed ID: 9722627
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor.
    Smith MD; Ensor EA; Coffin RS; Boxer LM; Latchman DS
    J Biol Chem; 1998 Jul; 273(27):16715-22. PubMed ID: 9642226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins.
    Smith MD; Dawson SJ; Latchman DS
    Mol Cell Biol; 1997 Jan; 17(1):345-54. PubMed ID: 8972215
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct domains of Brn-3a regulate apoptosis and neurite outgrowth in vivo.
    Faulkes DJ; Ensor E; Le Rouzic E; Latchman DS
    Neuroreport; 2004 Jun; 15(9):1421-5. PubMed ID: 15194866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The effects of Brn-3a on neuronal differentiation and apoptosis are differentially modulated by EWS and its oncogenic derivative EWS/Fli-1.
    Gascoyne DM; Thomas GR; Latchman DS
    Oncogene; 2004 May; 23(21):3830-40. PubMed ID: 15021903
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Brn-3a, a neuronal transcription factor of the POU gene family: indications for its involvement in cancer and angiogenesis.
    Chiarugi V; Del Rosso M; Magnelli L
    Mol Biotechnol; 2002 Oct; 22(2):123-7. PubMed ID: 12405260
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interaction between Brn-3a and Src-1 co-activates Brn-3a-mediated transactivation.
    Dennis JH; Budhram-Mahadeo V; Latchman DS
    Biochem Biophys Res Commun; 2002 Jun; 294(2):487-95. PubMed ID: 12051737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53.
    Sugars KL; Budhram-Mahadeo V; Packham G; Latchman DS
    Nucleic Acids Res; 2001 Nov; 29(22):4530-40. PubMed ID: 11713302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Brn-3a transcription factor.
    Latchman DS
    Int J Biochem Cell Biol; 1998 Nov; 30(11):1153-7. PubMed ID: 9839440
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Brn-3c transcription factor contains a neuronal-specific activation domain.
    Smith MD; Morris PJ; Latchman DS
    Neuroreport; 1998 Mar; 9(5):851-6. PubMed ID: 9579678
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor.
    Budhram-Mahadeo V; Morris PJ; Smith MD; Midgley CA; Boxer LM; Latchman DS
    J Biol Chem; 1999 May; 274(21):15237-44. PubMed ID: 10329733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells.
    Budhram-Mahadeo V; Morris P; Ndisang D; Irshad S; Lozano G; Pedley B; Latchman DS
    Neurosci Lett; 2002 Dec; 334(1):1-4. PubMed ID: 12431761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis.
    Budhram-Mahadeo V; Moore A; Morris PJ; Ward T; Weber B; Sassone-Corsi P; Latchman DS
    Int J Biochem Cell Biol; 2001 Oct; 33(10):1027-39. PubMed ID: 11470235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis.
    Ensor E; Smith MD; Latchman DS
    J Biol Chem; 2001 Feb; 276(7):5204-12. PubMed ID: 11053412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.
    Hudson CD; Morris PJ; Latchman DS; Budhram-Mahadeo VS
    J Biol Chem; 2005 Mar; 280(12):11851-8. PubMed ID: 15598651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitro.
    Smith MD; Melton LA; Ensor EA; Packham G; Anderson P; Kinloch RA; Latchman DS
    Mol Cell Neurosci; 2001 Mar; 17(3):460-70. PubMed ID: 11273642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor.
    Smith MD; Morris PJ; Dawson SJ; Schwartz ML; Schlaepfer WW; Latchman DS
    J Biol Chem; 1997 Aug; 272(34):21325-33. PubMed ID: 9261145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.
    Morris PJ; Theil T; Ring CJ; Lillycrop KA; Moroy T; Latchman DS
    Mol Cell Biol; 1994 Oct; 14(10):6907-14. PubMed ID: 7935408
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The pro-oncoprotein EWS (Ewing's Sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription.
    Thomas GR; Latchman DS
    Cancer Biol Ther; 2002; 1(4):428-32. PubMed ID: 12432261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c.
    Milton NG; Bessis A; Changeux JP; Latchman DS
    J Biol Chem; 1995 Jun; 270(25):15143-7. PubMed ID: 7797498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.