428 related articles for article (PubMed ID: 9730826)
1. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.
Wang H; Dick R; Yin H; Licad-Coles E; Kroetz DL; Szklarz G; Harlow G; Halpert JR; Correia MA
Biochemistry; 1998 Sep; 37(36):12536-45. PubMed ID: 9730826
[TBL] [Abstract][Full Text] [Related]
2. Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.
Xue L; Wang HF; Wang Q; Szklarz GD; Domanski TL; Halpert JR; Correia MA
Chem Res Toxicol; 2001 May; 14(5):483-91. PubMed ID: 11368545
[TBL] [Abstract][Full Text] [Related]
3. Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5' modification, purification, spectral characterization, reconstitution conditions, and catalytic activities.
Gillam EM; Guo Z; Ueng YF; Yamazaki H; Cock I; Reilly PE; Hooper WD; Guengerich FP
Arch Biochem Biophys; 1995 Mar; 317(2):374-84. PubMed ID: 7893152
[TBL] [Abstract][Full Text] [Related]
4. Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver.
Shou M; Martinet M; Korzekwa KR; Krausz KW; Gonzalez FJ; Gelboin HV
Pharmacogenetics; 1998 Oct; 8(5):391-401. PubMed ID: 9825831
[TBL] [Abstract][Full Text] [Related]
5. Cooperativity in oxidations catalyzed by cytochrome P450 3A4.
Ueng YF; Kuwabara T; Chun YJ; Guengerich FP
Biochemistry; 1997 Jan; 36(2):370-81. PubMed ID: 9003190
[TBL] [Abstract][Full Text] [Related]
6. Structure-function relationships of rat liver CYP3A9 to its human liver orthologs: site-directed active site mutagenesis to a progesterone dihydroxylase.
Xue L; Zgoda VG; Arison B; Correia MA
Arch Biochem Biophys; 2003 Jan; 409(1):113-26. PubMed ID: 12464250
[TBL] [Abstract][Full Text] [Related]
7. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.
Gallagher EP; Kunze KL; Stapleton PL; Eaton DL
Toxicol Appl Pharmacol; 1996 Dec; 141(2):595-606. PubMed ID: 8975785
[TBL] [Abstract][Full Text] [Related]
8. Differential inhibition of aflatoxin B1 oxidation by gestodene action on human liver microsomes.
Kim BR; Oh HS; Kim DH
Biochem Mol Biol Int; 1997 Nov; 43(4):839-46. PubMed ID: 9385444
[TBL] [Abstract][Full Text] [Related]
9. Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes.
Ueng YF; Shimada T; Yamazaki H; Guengerich FP
Chem Res Toxicol; 1995 Mar; 8(2):218-25. PubMed ID: 7766804
[TBL] [Abstract][Full Text] [Related]
10. Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome p450 3A enzymes.
He YQ; Roussel F; Halpert JR
Arch Biochem Biophys; 2001 May; 389(2):264-70. PubMed ID: 11339816
[TBL] [Abstract][Full Text] [Related]
11. Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.
Kamdem LK; Meineke I; Gödtel-Armbrust U; Brockmöller J; Wojnowski L
Chem Res Toxicol; 2006 Apr; 19(4):577-86. PubMed ID: 16608170
[TBL] [Abstract][Full Text] [Related]
12. Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity.
Pelkonen P; Lang MA; Negishi M; Wild CP; Juvonen RO
Chem Res Toxicol; 1997 Jan; 10(1):85-90. PubMed ID: 9074807
[TBL] [Abstract][Full Text] [Related]
13. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP
J Biol Chem; 1996 Nov; 271(44):27438-44. PubMed ID: 8910324
[TBL] [Abstract][Full Text] [Related]
14. Expression of cytochrome P450 3A7 in Escherichia coli: effects of 5' modification and catalytic characterization of recombinant enzyme expressed in bicistronic format with NADPH-cytochrome P450 reductase.
Gillam EM; Wunsch RM; Ueng YF; Shimada T; Reilly PE; Kamataki T; Guengerich FP
Arch Biochem Biophys; 1997 Oct; 346(1):81-90. PubMed ID: 9328287
[TBL] [Abstract][Full Text] [Related]
15. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
Gallagher EP; Wienkers LC; Stapleton PL; Kunze KL; Eaton DL
Cancer Res; 1994 Jan; 54(1):101-8. PubMed ID: 8261428
[TBL] [Abstract][Full Text] [Related]
16. Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs.
Mancy A; Antignac M; Minoletti C; Dijols S; Mouries V; Duong NT; Battioni P; Dansette PM; Mansuy D
Biochemistry; 1999 Oct; 38(43):14264-70. PubMed ID: 10572000
[TBL] [Abstract][Full Text] [Related]
17. Structure-function analysis of human cytochrome P-450 2B6 using a novel substrate, site-directed mutagenesis, and molecular modeling.
Domanski TL; Schultz KM; Roussel F; Stevens JC; Halpert JR
J Pharmacol Exp Ther; 1999 Sep; 290(3):1141-7. PubMed ID: 10454488
[TBL] [Abstract][Full Text] [Related]
18. Subcellular localization, aggregation state, and catalytic activity of microsomal P450 cytochromes modified in the NH2-terminal region and expressed in Escherichia coli.
Pernecky SJ; Olken NM; Bestervelt LL; Coon MJ
Arch Biochem Biophys; 1995 Apr; 318(2):446-56. PubMed ID: 7733676
[TBL] [Abstract][Full Text] [Related]
19. Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.
Szklarz GD; He YQ; Kedzie KM; Halpert JR; Burnett VL
Arch Biochem Biophys; 1996 Mar; 327(2):308-18. PubMed ID: 8619620
[TBL] [Abstract][Full Text] [Related]
20. Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity.
Harlow GR; Halpert JR
J Biol Chem; 1997 Feb; 272(9):5396-402. PubMed ID: 9038138
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
