370 related articles for article (PubMed ID: 9731497)
1. Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.
Rubsam LZ; Davidson BL; Shewach DS
Cancer Res; 1998 Sep; 58(17):3873-82. PubMed ID: 9731497
[TBL] [Abstract][Full Text] [Related]
2. Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells.
Rubsam LZ; Boucher PD; Murphy PJ; KuKuruga M; Shewach DS
Cancer Res; 1999 Feb; 59(3):669-75. PubMed ID: 9973216
[TBL] [Abstract][Full Text] [Related]
3. Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
Shewach DS; Zerbe LK; Hughes TL; Roessler BJ; Breakefield XO; Davidson BL
Cancer Gene Ther; 1994 Jun; 1(2):107-12. PubMed ID: 7621241
[TBL] [Abstract][Full Text] [Related]
4. Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir-mediated cytoxicity by hydroxyurea.
Boucher PD; Ostruszka LJ; Shewach DS
Cancer Res; 2000 Mar; 60(6):1631-6. PubMed ID: 10749133
[TBL] [Abstract][Full Text] [Related]
5. (E)-5-(2-bromovinyl)-2'-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase--expressing cells.
Hamel W; Zirkel D; Mehdorn HM; Westphal M; Israel MA
Cancer Gene Ther; 2001 May; 8(5):388-96. PubMed ID: 11477459
[TBL] [Abstract][Full Text] [Related]
6. Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin.
Hayashi K; Hayashi T; Sun HD; Takeda Y
Cancer Gene Ther; 2000 Jan; 7(1):45-52. PubMed ID: 10678355
[TBL] [Abstract][Full Text] [Related]
7. Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: implications for gene therapeutic approaches.
Thust R; Tomicic M; Klöcking R; Voutilainen N; Wutzler P; Kaina B
Cancer Gene Ther; 2000 Jan; 7(1):107-17. PubMed ID: 10678363
[TBL] [Abstract][Full Text] [Related]
8. Differential cytotoxicity and bystander effect of the rabbit cytochrome P450 4B1 enzyme gene by two different prodrugs: implications for pharmacogene therapy.
Frank S; Steffens S; Fischer U; Tlolko A; Rainov NG; Kramm CM
Cancer Gene Ther; 2002 Feb; 9(2):178-88. PubMed ID: 11857036
[TBL] [Abstract][Full Text] [Related]
9. BCR-ABL-expressing cells transduced with the HSV-tk gene die by apoptosis upon treatment with ganciclovir.
Rivas C; Miller AR; Collado M; Lam EW; Apperley JF; Melo JV
Mol Ther; 2001 May; 3(5 Pt 1):642-52. PubMed ID: 11356068
[TBL] [Abstract][Full Text] [Related]
10. Polyamine depletion and cell cycle manipulation in combination with HSV thymidine kinase/ganciclovir cancer gene therapy.
Wahlfors T; Karppinen A; Jänne J; Alhonen L; Wahlfors J
Int J Oncol; 2006 Jun; 28(6):1515-22. PubMed ID: 16685452
[TBL] [Abstract][Full Text] [Related]
11. Connexin-independent ganciclovir-mediated killing conferred on bystander effect-resistant cell lines by a herpes simplex virus-thymidine kinase-expressing colon cell line.
Drake RR; Pitlyk K; McMasters RA; Mercer KE; Young H; Moyer MP
Mol Ther; 2000 Nov; 2(5):515-23. PubMed ID: 11082325
[TBL] [Abstract][Full Text] [Related]
12. Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing.
Black ME; Kokoris MS; Sabo P
Cancer Res; 2001 Apr; 61(7):3022-6. PubMed ID: 11306482
[TBL] [Abstract][Full Text] [Related]
13. Differential chemosensitivity of breast cancer cells to ganciclovir treatment following adenovirus-mediated herpes simplex virus thymidine kinase gene transfer.
Li PX; Ngo D; Brade AM; Klamut HJ
Cancer Gene Ther; 1999; 6(2):179-90. PubMed ID: 10195885
[TBL] [Abstract][Full Text] [Related]
14. Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene.
van der Eb MM; Geutskens SB; van Kuilenburg AB; van Lenthe H; van Dierendonck JH; Kuppen PJ; van Ormondt H; van de Velde CJ; Wanders RJ; van Gennip AH; Hoeben RC
J Gene Med; 2003 Dec; 5(12):1018-27. PubMed ID: 14661177
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of prodrugs ability to induce effective ablation of cells transduced with viral thymidine kinase gene.
Kuriyama S; Nakatani T; Masui K; Sakamoto T; Tominaga K; Yoshikawa M; Fukui H; Ikenaka K; Tsujii T
Anticancer Res; 1996; 16(5A):2623-8. PubMed ID: 8917361
[TBL] [Abstract][Full Text] [Related]
16. [Adenovirus-mediated herpes simplex virus thymidine kinase gene transference and combined drug therapy leads to apoptosis of human epithelial ovarian cancer cells].
Jiang J; Kong B; Jiang S
Zhonghua Fu Chan Ke Za Zhi; 2000 Dec; 35(12):736-9. PubMed ID: 11286034
[TBL] [Abstract][Full Text] [Related]
17. Herpesvirus saimiri pathogenicity enhanced by thymidine kinase of herpes simplex virus.
Hiller C; Tamgüney G; Stolte N; Mätz-Rensing K; Lorenzen D; Hör S; Thurau M; Wittmann S; Slavin S; Fickenscher H
Virology; 2000 Dec; 278(2):445-55. PubMed ID: 11118367
[TBL] [Abstract][Full Text] [Related]
18. [Bystander effect mediated by herpes simplex virus-thymidine kinase/ganciclovir approach on prostatic cancer cells and its regulation].
Xing Y; Lu G; Xiao Y; Zeng F; Zhang Q; Xiong P; Feng W
Zhonghua Yi Xue Za Zhi; 2002 Nov; 82(21):1484-7. PubMed ID: 12509912
[TBL] [Abstract][Full Text] [Related]
19. Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.
Shewach DS; Murphy PJ; Robinson BW; Vuletich J; Boucher PD; Blobaum AL; Zerbe L; Secrist JA; Parker WB
Hum Gene Ther; 2002 Mar; 13(4):543-51. PubMed ID: 11874632
[TBL] [Abstract][Full Text] [Related]
20. Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1.
Bae PK; Kim JH; Kim HS; Chung IK; Paik SG; Lee CK
Antiviral Res; 2006 Jul; 70(3):93-104. PubMed ID: 16546268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]