BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 9731508)

  • 1. Regulation of expression of the DNA repair gene O6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling.
    Boldogh I; Ramana CV; Chen Z; Biswas T; Hazra TK; Grösch S; Grombacher T; Mitra S; Kaina B
    Cancer Res; 1998 Sep; 58(17):3950-6. PubMed ID: 9731508
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of human O6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone.
    Biswas T; Ramana CV; Srinivasan G; Boldogh I; Hazra TK; Chen Z; Tano K; Thompson EB; Mitra S
    Oncogene; 1999 Jan; 18(2):525-32. PubMed ID: 9927209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents.
    Grombacher T; Eichhorn U; Kaina B
    Oncogene; 1998 Aug; 17(7):845-51. PubMed ID: 9780001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
    Sato K; Kitajima Y; Nakagawachi T; Soejima H; Miyoshi A; Koga Y; Miyazaki K
    Oncol Rep; 2005 May; 13(5):899-906. PubMed ID: 15809756
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
    Srivenugopal KS; Shou J; Mullapudi SR; Lang FF; Rao JS; Ali-Osman F
    Clin Cancer Res; 2001 May; 7(5):1398-409. PubMed ID: 11350911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Kokkinakis DM; Ahmed MM; Delgado R; Fruitwala MM; Mohiuddin M; Albores-Saavedra J
    Cancer Res; 1997 Dec; 57(23):5360-8. PubMed ID: 9393761
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of 1,3-bis-(2-chloroethyl)-1-nitrosourea resistance in human tumor cells using hammerhead ribozymes designed to degrade O6-methylguanine DNA methyltransferase mRNA.
    Zhang Q; Ohannesian DW; Kreklau EL; Erickson LC
    J Pharmacol Exp Ther; 2001 Jul; 298(1):141-7. PubMed ID: 11408535
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.
    Hermes M; Geisler H; Osswald H; Riehle R; Kloor D
    Biochem Pharmacol; 2008 Jun; 75(11):2100-11. PubMed ID: 18395186
    [TBL] [Abstract][Full Text] [Related]  

  • 10. O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma.
    Zuo C; Ai L; Ratliff P; Suen JY; Hanna E; Brent TP; Fan CY
    Cancer Epidemiol Biomarkers Prev; 2004 Jun; 13(6):967-75. PubMed ID: 15184253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.
    Ma LC; Kuo CC; Liu JF; Chen LT; Chang JY
    Mol Pharmacol; 2008 Aug; 74(2):517-26. PubMed ID: 18492797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
    Bhakat KK; Mitra S
    Carcinogenesis; 2003 Aug; 24(8):1337-45. PubMed ID: 12807730
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase.
    Lavon I; Fuchs D; Zrihan D; Efroni G; Zelikovitch B; Fellig Y; Siegal T
    Cancer Res; 2007 Sep; 67(18):8952-9. PubMed ID: 17875738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.
    Blough MD; Zlatescu MC; Cairncross JG
    Cancer Res; 2007 Jan; 67(2):580-4. PubMed ID: 17234766
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells.
    Harris LC; Potter PM; Remack JS; Brent TP
    Cancer Res; 1992 Nov; 52(22):6404-6. PubMed ID: 1423289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors.
    Yin D; Xie D; Hofmann WK; Zhang W; Asotra K; Wong R; Black KL; Koeffler HP
    Mol Carcinog; 2003 Jan; 36(1):23-31. PubMed ID: 12503076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Study on MGMT assay and tumor individual predictable chemotherapy].
    Zhang YP
    Ai Zheng; 2004 Jun; 23(6):724-34. PubMed ID: 15191682
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC; Liu JF; Chang JY
    J Pharmacol Exp Ther; 2006 Feb; 316(2):946-54. PubMed ID: 16258022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The alleles of the DNA repair gene O6-alkylguanine-DNA alkyltransferase are expressed at different levels in normal human lung tissue.
    Heighway J; Margison GP; Santibáñez-Koref MF
    Carcinogenesis; 2003 Oct; 24(10):1691-4. PubMed ID: 12896905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.