234 related articles for article (PubMed ID: 9733481)
1. Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K.
Marquis RW; Yamashita DS; Ru Y; LoCastro SM; Oh HJ; Erhard KF; DesJarlais RL; Head MS; Smith WW; Zhao B; Janson CA; Abdel-Meguid SS; Tomaszek TA; Levy MA; Veber DF
J Med Chem; 1998 Sep; 41(19):3563-7. PubMed ID: 9733481
[No Abstract] [Full Text] [Related]
2. Structure-based design of cathepsin K inhibitors containing a benzyloxy-substituted benzoyl peptidomimetic.
Thompson SK; Smith WW; Zhao B; Halbert SM; Tomaszek TA; Tew DG; Levy MA; Janson CA; DAlessio KJ; McQueney MS; Kurdyla J; Jones CS; DesJarlais RL; Abdel-Meguid SS; Veber DF
J Med Chem; 1998 Oct; 41(21):3923-7. PubMed ID: 9767629
[TBL] [Abstract][Full Text] [Related]
3. Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.
Barrett DG; Catalano JG; Deaton DN; Hassell AM; Long ST; Miller AB; Miller LR; Ray JA; Samano V; Shewchuk LM; Wells-Knecht KJ; Willard DH; Wright LL
Bioorg Med Chem Lett; 2006 Mar; 16(6):1735-9. PubMed ID: 16376075
[TBL] [Abstract][Full Text] [Related]
4. Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.
Tavares FX; Boncek V; Deaton DN; Hassell AM; Long ST; Miller AB; Payne AA; Miller LR; Shewchuk LM; Wells-Knecht K; Willard DH; Wright LL; Zhou HQ
J Med Chem; 2004 Jan; 47(3):588-99. PubMed ID: 14736240
[TBL] [Abstract][Full Text] [Related]
5. P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.
Barrett DG; Boncek VM; Catalano JG; Deaton DN; Hassell AM; Jurgensen CH; Long ST; McFadyen RB; Miller AB; Miller LR; Payne JA; Ray JA; Samano V; Shewchuk LM; Tavares FX; Wells-Knecht KJ; Willard DH; Wright LL; Zhou HQ
Bioorg Med Chem Lett; 2005 Aug; 15(15):3540-6. PubMed ID: 15982880
[TBL] [Abstract][Full Text] [Related]
6. Benzodioxocin-3-ones and N-acyl-3-amino-3-buten-2-ones: novel classes of cathepsin K cysteine protease inhibitors.
Yamashita DS; Xie R; Lin H; Wang B; Shi SD; Quinn CJ; Hemling ME; Hissong C; Tomaszek TA; Veber DF
J Pept Res; 2004 Mar; 63(3):265-9. PubMed ID: 15049838
[TBL] [Abstract][Full Text] [Related]
7. Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K.
Altmann E; Cowan-Jacob SW; Missbach M
J Med Chem; 2004 Nov; 47(24):5833-6. PubMed ID: 15537340
[TBL] [Abstract][Full Text] [Related]
8. Acyclic, orally bioavailable ketone-based cathepsin K inhibitors.
Barrett DG; Catalano JG; Deaton DN; Long ST; McFadyen RB; Miller AB; Miller LR; Samano V; Tavares FX; Wells-Knecht KJ; Wright LL; Zhou HQ
Bioorg Med Chem Lett; 2007 Jan; 17(1):22-7. PubMed ID: 17157021
[TBL] [Abstract][Full Text] [Related]
9. Arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 2: Optimization of P1 and N-aryl.
Alper PB; Liu H; Chatterjee AK; Nguyen KT; Tully DC; Tumanut C; Li J; Harris JL; Tuntland T; Chang J; Gordon P; Hollenbeck T; Karanewsky DS
Bioorg Med Chem Lett; 2006 Mar; 16(6):1486-90. PubMed ID: 16412634
[TBL] [Abstract][Full Text] [Related]
10. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid.
Schirmeister T
J Med Chem; 1999 Feb; 42(4):560-72. PubMed ID: 10052963
[TBL] [Abstract][Full Text] [Related]
11. 3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity.
Setti EL; Davis D; Janc JW; Jeffery DA; Cheung H; Yu W
Bioorg Med Chem Lett; 2005 Mar; 15(5):1529-34. PubMed ID: 15713422
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K.
Duffy KJ; Ridgers LH; DesJarlais RL; Tomaszek TA; Bossard MJ; Thompson SK; Keenan RM; Veber DF
Bioorg Med Chem Lett; 1999 Jul; 9(14):1907-10. PubMed ID: 10450951
[TBL] [Abstract][Full Text] [Related]
13. Novel and potent cyclic cyanamide-based cathepsin K inhibitors.
Deaton DN; Hassell AM; McFadyen RB; Miller AB; Miller LR; Shewchuk LM; Tavares FX; Willard DH; Wright LL
Bioorg Med Chem Lett; 2005 Apr; 15(7):1815-9. PubMed ID: 15780613
[TBL] [Abstract][Full Text] [Related]
14. Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K.
Fenwick AE; Garnier B; Gribble AD; Ife RJ; Rawlings AD; Witherington J
Bioorg Med Chem Lett; 2001 Jan; 11(2):195-8. PubMed ID: 11206457
[TBL] [Abstract][Full Text] [Related]
15. Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.
Barrett DG; Catalano JG; Deaton DN; Hassell AM; Long ST; Miller AB; Miller LR; Shewchuk LM; Wells-Knecht KJ; Willard DH; Wright LL
Bioorg Med Chem Lett; 2004 Oct; 14(19):4897-902. PubMed ID: 15341947
[TBL] [Abstract][Full Text] [Related]
16. 2-Cyano-pyrimidines: a new chemotype for inhibitors of the cysteine protease cathepsin K.
Altmann E; Aichholz R; Betschart C; Buhl T; Green J; Irie O; Teno N; Lattmann R; Tintelnot-Blomley M; Missbach M
J Med Chem; 2007 Feb; 50(4):591-4. PubMed ID: 17256925
[TBL] [Abstract][Full Text] [Related]
17. Potent and selective ketoamide-based inhibitors of cysteine protease, cathepsin K.
Tavares FX; Deaton DN; Miller AB; Miller LR; Wright LL; Zhou HQ
J Med Chem; 2004 Oct; 47(21):5049-56. PubMed ID: 15456248
[TBL] [Abstract][Full Text] [Related]
18. Dioxo-triazines as a novel series of cathepsin K inhibitors.
Rankovic Z; Cai J; Fradera X; Dempster M; Mistry A; Mitchell A; Long C; Hamilton E; King A; Boucharens S; Jamieson C; Gillespie J; Cumming I; Uitdehaag J; van Zeeland M
Bioorg Med Chem Lett; 2010 Mar; 20(5):1488-90. PubMed ID: 20153187
[TBL] [Abstract][Full Text] [Related]
19. Discovery and parallel synthesis of a new class of cathepsin K inhibitors.
Smith RA; Bhargava A; Browe C; Chen J; Dumas J; Hatoum-Mokdad H; Romero R
Bioorg Med Chem Lett; 2001 Nov; 11(22):2951-4. PubMed ID: 11677133
[TBL] [Abstract][Full Text] [Related]
20. Identification of a potent and selective non-basic cathepsin K inhibitor.
Li CS; Deschenes D; Desmarais S; Falgueyret JP; Gauthier JY; Kimmel DB; Léger S; Massé F; McGrath ME; McKay DJ; Percival MD; Riendeau D; Rodan SB; Thérien M; Truong VL; Wesolowski G; Zamboni R; Black WC
Bioorg Med Chem Lett; 2006 Apr; 16(7):1985-9. PubMed ID: 16413777
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
