These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 9737679)

  • 1. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product.
    Kiyoi H; Towatari M; Yokota S; Hamaguchi M; Ohno R; Saito H; Naoe T
    Leukemia; 1998 Sep; 12(9):1333-7. PubMed ID: 9737679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.
    Yamamoto Y; Kiyoi H; Nakano Y; Suzuki R; Kodera Y; Miyawaki S; Asou N; Kuriyama K; Yagasaki F; Shimazaki C; Akiyama H; Saito K; Nishimura M; Motoji T; Shinagawa K; Takeshita A; Saito H; Ueda R; Ohno R; Naoe T
    Blood; 2001 Apr; 97(8):2434-9. PubMed ID: 11290608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Better detection of FLT3 internal tandem duplication using peripheral blood plasma DNA.
    Jilani I; Estey E; Manshuri T; Caligiuri M; Keating M; Giles F; Thomas D; Kantarjian H; Albitar M
    Leukemia; 2003 Jan; 17(1):114-9. PubMed ID: 12529667
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain.
    Kiyoi H; Ohno R; Ueda R; Saito H; Naoe T
    Oncogene; 2002 Apr; 21(16):2555-63. PubMed ID: 11971190
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FLT3 mutations in acute myeloid leukemia cell lines.
    Quentmeier H; Reinhardt J; Zaborski M; Drexler HG
    Leukemia; 2003 Jan; 17(1):120-4. PubMed ID: 12529668
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Internal tandem duplication of fms-like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome.
    Shih LY; Lin TL; Wang PN; Wu JH; Dunn P; Kuo MC; Huang CF
    Cancer; 2004 Sep; 101(5):989-98. PubMed ID: 15329908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FLT3/ITD mutation signaling includes suppression of SHP-1.
    Chen P; Levis M; Brown P; Kim KT; Allebach J; Small D
    J Biol Chem; 2005 Feb; 280(7):5361-9. PubMed ID: 15574429
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines.
    Yokota S; Kiyoi H; Nakao M; Iwai T; Misawa S; Okuda T; Sonoda Y; Abe T; Kahsima K; Matsuo Y; Naoe T
    Leukemia; 1997 Oct; 11(10):1605-9. PubMed ID: 9324277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor.
    Grundler R; Thiede C; Miething C; Steudel C; Peschel C; Duyster J
    Blood; 2003 Jul; 102(2):646-51. PubMed ID: 12663439
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase.
    Komeno Y; Kurokawa M; Imai Y; Takeshita M; Matsumura T; Kubo K; Yoshino T; Nishiyama U; Kuwaki T; Kubo K; Osawa T; Ogawa S; Chiba S; Miwa A; Hirai H
    Leukemia; 2005 Jun; 19(6):930-5. PubMed ID: 15815726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia.
    Shih LY; Huang CF; Wang PN; Wu JH; Lin TL; Dunn P; Kuo MC
    Leukemia; 2004 Mar; 18(3):466-75. PubMed ID: 14737077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.
    Nakao M; Yokota S; Iwai T; Kaneko H; Horiike S; Kashima K; Sonoda Y; Fujimoto T; Misawa S
    Leukemia; 1996 Dec; 10(12):1911-8. PubMed ID: 8946930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clinical impact of internal tandem duplications and activating point mutations in FLT3 in acute myeloid leukemia in elderly patients.
    Andersson A; Johansson B; Lassen C; Mitelman F; Billström R; Fioretos T
    Eur J Haematol; 2004 May; 72(5):307-13. PubMed ID: 15059064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prognostic significance of FLT3 ITD and D835 mutations in AML patients.
    Sheikhha MH; Awan A; Tobal K; Liu Yin JA
    Hematol J; 2003; 4(1):41-6. PubMed ID: 12692519
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.
    Schwäble J; Choudhary C; Thiede C; Tickenbrock L; Sargin B; Steur C; Rehage M; Rudat A; Brandts C; Berdel WE; Müller-Tidow C; Serve H
    Blood; 2005 Mar; 105(5):2107-14. PubMed ID: 15536149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FLT3-TKD mutation in childhood acute myeloid leukemia.
    Liang DC; Shih LY; Hung IJ; Yang CP; Chen SH; Jaing TH; Liu HC; Wang LY; Chang WH
    Leukemia; 2003 May; 17(5):883-6. PubMed ID: 12750701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor.
    Tse KF; Allebach J; Levis M; Smith BD; Bohmer FD; Small D
    Leukemia; 2002 Oct; 16(10):2027-36. PubMed ID: 12357354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.
    Whitman SP; Archer KJ; Feng L; Baldus C; Becknell B; Carlson BD; Carroll AJ; Mrózek K; Vardiman JW; George SL; Kolitz JE; Larson RA; Bloomfield CD; Caligiuri MA
    Cancer Res; 2001 Oct; 61(19):7233-9. PubMed ID: 11585760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.
    Yang X; Liu L; Sternberg D; Tang L; Galinsky I; DeAngelo D; Stone R
    Cancer Res; 2005 Aug; 65(16):7338-47. PubMed ID: 16103085
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group.
    Abu-Duhier FM; Goodeve AC; Wilson GA; Gari MA; Peake IR; Rees DC; Vandenberghe EA; Winship PR; Reilly JT
    Br J Haematol; 2000 Oct; 111(1):190-5. PubMed ID: 11091200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.