167 related articles for article (PubMed ID: 9748136)
1. Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy.
Zhang L; Taub JW; Williamson M; Wong SC; Hukku B; Pullen J; Ravindranath Y; Matherly LH
Clin Cancer Res; 1998 Sep; 4(9):2169-77. PubMed ID: 9748136
[TBL] [Abstract][Full Text] [Related]
2. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
Belkov VM; Krynetski EY; Schuetz JD; Yanishevski Y; Masson E; Mathew S; Raimondi S; Pui CH; Relling MV; Evans WE
Blood; 1999 Mar; 93(5):1643-50. PubMed ID: 10029593
[TBL] [Abstract][Full Text] [Related]
3. Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
Ding BC; Witt TL; Hukku B; Heng H; Zhang L; Matherly LH
Biochem Pharmacol; 2001 Mar; 61(6):665-75. PubMed ID: 11266651
[TBL] [Abstract][Full Text] [Related]
4. Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.
Gorlick R; Goker E; Trippett T; Steinherz P; Elisseyeff Y; Mazumdar M; Flintoff WF; Bertino JR
Blood; 1997 Feb; 89(3):1013-8. PubMed ID: 9028333
[TBL] [Abstract][Full Text] [Related]
5. Reduced folate carrier mutations are not the mechanism underlying methotrexate resistance in childhood acute lymphoblastic leukemia.
Kaufman Y; Drori S; Cole PD; Kamen BA; Sirota J; Ifergan I; Arush MW; Elhasid R; Sahar D; Kaspers GJ; Jansen G; Matherly LH; Rechavi G; Toren A; Assaraf YG
Cancer; 2004 Feb; 100(4):773-82. PubMed ID: 14770434
[TBL] [Abstract][Full Text] [Related]
6. Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.
Levy AS; Sather HN; Steinherz PG; Sowers R; La M; Moscow JA; Gaynon PS; Uckun FM; Bertino JR; Gorlick R;
J Pediatr Hematol Oncol; 2003 Sep; 25(9):688-95. PubMed ID: 12972803
[TBL] [Abstract][Full Text] [Related]
7. Variable expression of RFC1 in human leukemia cell lines resistant to antifolates.
Kobayashi H; Takemura Y; Ohnuma T
Cancer Lett; 1998 Feb; 124(2):135-42. PubMed ID: 9500202
[TBL] [Abstract][Full Text] [Related]
8. Methotrexate pharmacology and resistance in childhood acute lymphoblastic leukemia.
Matherly LH; Taub JW
Leuk Lymphoma; 1996 May; 21(5-6):359-68. PubMed ID: 9172800
[TBL] [Abstract][Full Text] [Related]
9. P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in methotrexate accumulation due to a point mutation in the reduced folate carrier gene.
Gifford AJ; Kavallaris M; Madafiglio J; Matherly LH; Stewart BW; Haber M; Norris MD
Int J Cancer; 1998 Oct; 78(2):176-81. PubMed ID: 9754649
[TBL] [Abstract][Full Text] [Related]
10. Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.
Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH
Clin Cancer Res; 2001 Nov; 7(11):3416-22. PubMed ID: 11705857
[TBL] [Abstract][Full Text] [Related]
11. Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start.
Flatley RM; Payton SG; Taub JW; Matherly LH
Clin Cancer Res; 2004 Aug; 10(15):5111-22. PubMed ID: 15297414
[TBL] [Abstract][Full Text] [Related]
12. Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.
Wong SC; Zhang L; Witt TL; Proefke SA; Bhushan A; Matherly LH
J Biol Chem; 1999 Apr; 274(15):10388-94. PubMed ID: 10187828
[TBL] [Abstract][Full Text] [Related]
13. Increased frequency of expression of elevated dihydrofolate reductase in T-cell versus B-precursor acute lymphoblastic leukemia in children.
Matherly LH; Taub JW; Wong SC; Simpson PM; Ekizian R; Buck S; Williamson M; Amylon M; Pullen J; Camitta B; Ravindranath Y
Blood; 1997 Jul; 90(2):578-89. PubMed ID: 9226157
[TBL] [Abstract][Full Text] [Related]
14. The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number.
Gregers J; Christensen IJ; Dalhoff K; Lausen B; Schroeder H; Rosthoej S; Carlsen N; Schmiegelow K; Peterson C
Blood; 2010 Jun; 115(23):4671-7. PubMed ID: 20335220
[TBL] [Abstract][Full Text] [Related]
15. Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation.
Gorlick R; Cole P; Banerjee D; Longo G; Li WW; Hochhauser D; Bertino JR
Adv Exp Med Biol; 1999; 457():543-50. PubMed ID: 10500832
[TBL] [Abstract][Full Text] [Related]
16. 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.
McGuire JJ; Haile WH; Yeh CC
Cancer Res; 2006 Apr; 66(7):3836-44. PubMed ID: 16585211
[TBL] [Abstract][Full Text] [Related]
17. The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Whitehead VM; Payment C; Cooley L; Lauer SJ; Mahoney DH; Shuster JJ; Vuchich MJ; Bernstein ML; Look AT; Pullen DJ; Camitta B
Leukemia; 2001 Jul; 15(7):1081-8. PubMed ID: 11455977
[TBL] [Abstract][Full Text] [Related]
18. Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.
Rothem L; Ifergan I; Kaufman Y; Priest DG; Jansen G; Assaraf YG
Biochem J; 2002 Nov; 367(Pt 3):741-50. PubMed ID: 12139489
[TBL] [Abstract][Full Text] [Related]
19. Gene amplification and increased expression of the reduced folate carrier in transport elevated K562 cells.
Wong SC; Zhang L; Proefke SA; Hukku B; Matherly LH
Biochem Pharmacol; 1998 Apr; 55(7):1135-8. PubMed ID: 9605439
[TBL] [Abstract][Full Text] [Related]
20. hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.
Borssén M; Cullman I; Norén-Nyström U; Sundström C; Porwit A; Forestier E; Roos G
Exp Hematol; 2011 Dec; 39(12):1144-51. PubMed ID: 21914494
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
