These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 9748140)

  • 41. Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer.
    Belvedere O; Puglisi F; Di Loreto C; Cataldi P; Guglielmi A; Aschele C; Sobrero A
    Ann Oncol; 2004 Jan; 15(1):55-8. PubMed ID: 14679120
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Cell cycle-dependent potentiation of cisplatin by UCN-01 in non-small-cell lung carcinoma.
    Mack PC; Gandara DR; Lau AH; Lara PN; Edelman MJ; Gumerlock PH
    Cancer Chemother Pharmacol; 2003 Apr; 51(4):337-48. PubMed ID: 12721762
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Rb dephosphorylation and suppression of E2F activity in human breast tumor cells exposed to a pharmacological concentration of estradiol.
    Gewirtz DA; Di YM; Randolph JK; Jain PT; Valerie K; Bullock S; Nath N; Chellappan SP
    Arch Biochem Biophys; 2001 Apr; 388(2):243-52. PubMed ID: 11368161
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells.
    Yang D; Qu J; Qu X; Cao Y; Xu L; Hou K; Feng W; Liu Y
    Cancer Chemother Pharmacol; 2015 Sep; 76(3):575-86. PubMed ID: 26208739
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.
    Haddad MM; Xu W; Schwahn DJ; Liao F; Medrano EE
    Exp Cell Res; 1999 Dec; 253(2):561-72. PubMed ID: 10585280
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Functional interplay between p53 and E2F through co-activator p300.
    Lee CW; Sørensen TS; Shikama N; La Thangue NB
    Oncogene; 1998 May; 16(21):2695-710. PubMed ID: 9652736
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.
    Bras-Gonçalves RA; Pocard M; Formento JL; Poirson-Bichat F; De Pinieux G; Pandrea I; Arvelo F; Ronco G; Villa P; Coquelle A; Milano G; Lesuffleur T; Dutrillaux B; Poupon MF
    Gastroenterology; 2001 Mar; 120(4):874-88. PubMed ID: 11231942
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells.
    Yang HL; Dong YB; Elliott MJ; Liu TJ; McMasters KM
    Clin Cancer Res; 2000 Apr; 6(4):1579-89. PubMed ID: 10778992
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
    Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
    [TBL] [Abstract][Full Text] [Related]  

  • 50. p53 and WAF1 are induced and Rb protein is hypophosphorylated during cell growth inhibition by the thymidylate synthase inhibitor ZD1694 (Tomudex).
    Yin MB; Voigt W; Panadero A; Vanhoefer U; Frank C; Pajovic S; Azizkhan J; Rustum YM
    Mol Pharmacol; 1997 Apr; 51(4):630-6. PubMed ID: 9106628
    [TBL] [Abstract][Full Text] [Related]  

  • 51. UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line.
    Kawakami K; Futami H; Takahara J; Yamaguchi K
    Biochem Biophys Res Commun; 1996 Feb; 219(3):778-83. PubMed ID: 8645257
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Inducible pRb2/p130 expression and growth-suppressive mechanisms: evidence of a pRb2/p130, p27Kip1, and cyclin E negative feedback regulatory loop.
    Howard CM; Claudio PP; De Luca A; Stiegler P; Jori FP; Safdar NM; Caputi M; Khalili K; Giordano A
    Cancer Res; 2000 May; 60(10):2737-44. PubMed ID: 10825149
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V; Lahusen T; Leethanakul C; Igishi T; Kremer M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS; Senderowicz AM
    Clin Cancer Res; 2002 Nov; 8(11):3549-60. PubMed ID: 12429646
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431.
    Ahmad N; Gupta S; Mukhtar H
    Oncogene; 1999 Mar; 18(10):1891-6. PubMed ID: 10086343
    [TBL] [Abstract][Full Text] [Related]  

  • 55. E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells.
    Elliott MJ; Farmer MR; Atienza C; Stilwell A; Dong YB; Yang HL; Wong SL; McMasters KM
    Tumour Biol; 2002; 23(2):76-86. PubMed ID: 12065845
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Flavopiridol-induced apoptosis during S phase requires E2F-1 and inhibition of cyclin A-dependent kinase activity.
    Jiang J; Matranga CB; Cai D; Latham VM; Zhang X; Lowell AM; Martelli F; Shapiro GI
    Cancer Res; 2003 Nov; 63(21):7410-22. PubMed ID: 14612540
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Topoisomerase IIalpha mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression.
    Nip J; Hiebert SW
    Cell Biochem Biophys; 2000; 33(2):199-207. PubMed ID: 11325040
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Expression level of thymidylate synthase mRNA reflects 5-fluorouracil sensitivity with low dose and long duration in primary colorectal cancer.
    Okumura K; Mekata E; Shiomi H; Naitoh H; Abe H; Endo Y; Kurumi Y; Tani T
    Cancer Chemother Pharmacol; 2008 Apr; 61(4):587-94. PubMed ID: 17520254
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
    Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Vitamin D mediates its action in human colon carcinoma cells in a calcium-sensing receptor-dependent manner: downregulates malignant cell behavior and the expression of thymidylate synthase and survivin and promotes cellular sensitivity to 5-FU.
    Liu G; Hu X; Chakrabarty S
    Int J Cancer; 2010 Feb; 126(3):631-9. PubMed ID: 19621386
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.