BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

40 related articles for article (PubMed ID: 9749838)

  • 1.
    Zein J; Gaston B; Bazeley P; DeBoer MD; Igo RP; Bleecker ER; Meyers D; Comhair S; Marozkina NV; Cotton C; Patel M; Alyamani M; Xu W; Busse WW; Calhoun WJ; Ortega V; Hawkins GA; Castro M; Chung KF; Fahy JV; Fitzpatrick AM; Israel E; Jarjour NN; Levy B; Mauger DT; Moore WC; Noel P; Peters SP; Teague WG; Wenzel SE; Erzurum SC; Sharifi N
    Proc Natl Acad Sci U S A; 2020 Jan; 117(4):2187-2193. PubMed ID: 31932420
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline HSD3B1 Genetics and Prostate Cancer Outcomes.
    Thomas L; Sharifi N
    Urology; 2020 Nov; 145():13-21. PubMed ID: 32866512
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione Transferases as Efficient Ketosteroid Isomerases.
    Mannervik B; Ismail A; Lindström H; Sjödin B; Ing NH
    Front Mol Biosci; 2021; 8():765970. PubMed ID: 34881290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bicyclo[3.2.0]carbocyclic Molecules and Redox Biotransformations: The Evolution of Closed-Loop Artificial Linear Biocatalytic Cascades and Related Redox-Neutral Systems.
    Willetts A
    Molecules; 2023 Oct; 28(21):. PubMed ID: 37959669
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of human 3β-hydroxysteroid dehydrogenase type 2 by adrenal corticosteroids and product-feedback by androstenedione in human adrenarche.
    Thomas JL; Rajapaksha M; Mack VL; DeMars GA; Majzoub JA; Bose HS
    J Pharmacol Exp Ther; 2015 Jan; 352(1):67-76. PubMed ID: 25355646
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lipid-mediated unfolding of 3β-hydroxysteroid dehydrogenase 2 is essential for steroidogenic activity.
    Rajapaksha M; Thomas JL; Streeter M; Prasad M; Whittal RM; Bell JD; Bose HS
    Biochemistry; 2011 Dec; 50(51):11015-24. PubMed ID: 22106846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 as a potential treatment for breast cancer.
    Thomas JL; Bucholtz KM; Kacsoh B
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):57-65. PubMed ID: 20736065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis.
    Thomas JL; Mack VL; Sun J; Terrell JR; Bucholtz KM
    J Steroid Biochem Mol Biol; 2010 Jun; 120(4-5):192-9. PubMed ID: 20420909
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes.
    Kavanagh KL; Jörnvall H; Persson B; Oppermann U
    Cell Mol Life Sci; 2008 Dec; 65(24):3895-906. PubMed ID: 19011750
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for the selective inhibition of human 3beta-hydroxysteroid dehydrogenase 1 in human breast tumor MCF-7 cells.
    Thomas JL; Bucholtz KM; Sun J; Mack VL; Kacsoh B
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):174-82. PubMed ID: 18955108
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure/function of the inhibition of human 3beta-hydroxysteroid dehydrogenase type 1 and type 2 by trilostane.
    Thomas JL; Mack VL; Glow JA; Moshkelani D; Terrell JR; Bucholtz KM
    J Steroid Biochem Mol Biol; 2008 Jul; 111(1-2):66-73. PubMed ID: 18524572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure/function of human type 1 3beta-hydroxysteroid dehydrogenase: An intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for substrate and coenzyme utilization.
    Thomas JL; Huether R; Mack VL; Scaccia LA; Stoner RC; Duax WL
    J Steroid Biochem Mol Biol; 2007 Oct; 107(1-2):80-7. PubMed ID: 17624763
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rational proteomics V: structure-based mutagenesis has revealed key residues responsible for substrate recognition and catalysis by the dehydrogenase and isomerase activities in human 3beta-hydroxysteroid dehydrogenase/isomerase type 1.
    Pletnev VZ; Thomas JL; Rhaney FL; Holt LS; Scaccia LA; Umland TC; Duax WL
    J Steroid Biochem Mol Biol; 2006 Sep; 101(1):50-60. PubMed ID: 16889958
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.
    Thomas JL; Boswell EL; Scaccia LA; Pletnev V; Umland TC
    J Biol Chem; 2005 Jun; 280(22):21321-8. PubMed ID: 15797861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.
    Thomas JL; Evans BW; Blanco G; Mercer RW; Mason JI; Adler S; Nash WE; Isenberg KE; Strickler RC
    J Steroid Biochem Mol Biol; 1998 Sep; 66(5-6):327-34. PubMed ID: 9749838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The engineered, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase: purification, characterization and crystallization.
    Thomas JL; Mason JI; Blanco G; Veisaga ML
    J Mol Endocrinol; 2001 Aug; 27(1):77-83. PubMed ID: 11463578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional activity of 3beta-hydroxysteroid dehydrogenase/isomerase.
    Mason JI; Naville D; Evans BW; Thomas JL
    Endocr Res; 1998; 24(3-4):549-57. PubMed ID: 9888536
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Creation of a fully active, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase by the deletion of a membrane-spanning domain.
    Thomas JL; Evans BW; Blanco G; Mason JI; Strickler RC
    J Mol Endocrinol; 1999 Oct; 23(2):231-9. PubMed ID: 10514560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family.
    Simard J; Ricketts ML; Gingras S; Soucy P; Feltus FA; Melner MH
    Endocr Rev; 2005 Jun; 26(4):525-82. PubMed ID: 15632317
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.