BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 9751500)

  • 1. Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors.
    Liu Y; Takeshita A; Misiti S; Chin WW; Yen PM
    Endocrinology; 1998 Oct; 139(10):4197-204. PubMed ID: 9751500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear corepressors enhance the dominant negative activity of mutant receptors that cause resistance to thyroid hormone.
    Tagami T; Jameson JL
    Endocrinology; 1998 Feb; 139(2):640-50. PubMed ID: 9449636
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.
    Safer JD; Cohen RN; Hollenberg AN; Wondisford FE
    J Biol Chem; 1998 Nov; 273(46):30175-82. PubMed ID: 9804773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.
    Tagami T; Gu WX; Peairs PT; West BL; Jameson JL
    Mol Endocrinol; 1998 Dec; 12(12):1888-902. PubMed ID: 9849963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of the functional role of steroid receptor coactivator-1 in ligand-induced transactivation by thyroid hormone receptor.
    Jeyakumar M; Tanen MR; Bagchi MK
    Mol Endocrinol; 1997 Jun; 11(6):755-67. PubMed ID: 9171239
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional analyses of an LXXLL motif in nuclear receptor corepressor (N-CoR).
    Loinder K; Söderström M
    J Steroid Biochem Mol Biol; 2004 Aug; 91(4-5):191-6. PubMed ID: 15336696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
    Shibata H; Spencer TE; Oñate SA; Jenster G; Tsai SY; Tsai MJ; O'Malley BW
    Recent Prog Horm Res; 1997; 52():141-64; discussion 164-5. PubMed ID: 9238851
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired interaction of mutant thyroid hormone receptors associated with human hepatocellular carcinoma with transcriptional coregulators.
    Lin KH; Wu YH; Chen SL
    Endocrinology; 2001 Feb; 142(2):653-62. PubMed ID: 11159836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative analysis of DNA binding affinity and dimerization properties of wild-type and mutant thyroid hormone receptor beta1.
    Takeda T; Nagasawa T; Miyamoto T; Minemura K; Hashizume K; Degroot LJ
    Thyroid; 2000 Jan; 10(1):11-8. PubMed ID: 10691308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resistance to thyroid hormone caused by two mutant thyroid hormone receptors beta, R243Q and R243W, with marked impairment of function that cannot be explained by altered in vitro 3,5,3'-triiodothyroinine binding affinity.
    Yagi H; Pohlenz J; Hayashi Y; Sakurai A; Refetoff S
    J Clin Endocrinol Metab; 1997 May; 82(5):1608-14. PubMed ID: 9141558
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Direct interactions between corepressors and coactivators permit the integration of nuclear receptor-mediated repression and activation.
    Li X; Kimbrel EA; Kenan DJ; McDonnell DP
    Mol Endocrinol; 2002 Jul; 16(7):1482-91. PubMed ID: 12089344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
    Wu SY; Cohen RN; Simsek E; Senses DA; Yar NE; Grasberger H; Noel J; Refetoff S; Weiss RE
    J Clin Endocrinol Metab; 2006 May; 91(5):1887-95. PubMed ID: 16464943
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathological Interactions Between Mutant Thyroid Hormone Receptors and Corepressors and Their Modulation by a Thyroid Hormone Analogue with Therapeutic Potential.
    Harrus D; Déméné H; Vasquez E; Boulahtouf A; Germain P; Figueira AC; Privalsky ML; Bourguet W; le Maire A
    Thyroid; 2018 Dec; 28(12):1708-1722. PubMed ID: 30235988
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG; Yu CL; McPhie P; Wong R; Cheng SY
    Endocrinology; 1996 Feb; 137(2):712-21. PubMed ID: 8593822
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TR surfaces and conformations required to bind nuclear receptor corepressor.
    Marimuthu A; Feng W; Tagami T; Nguyen H; Jameson JL; Fletterick RJ; Baxter JD; West BL
    Mol Endocrinol; 2002 Feb; 16(2):271-86. PubMed ID: 11818500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor.
    Jeyakumar M; Webb P; Baxter JD; Scanlan TS; Katzenellenbogen JA
    Biochemistry; 2008 Jul; 47(28):7465-76. PubMed ID: 18558711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of nuclear coactivator and corepressor expression in mouse cerebellum by thyroid hormone.
    Ramos HE; Weiss RE
    Thyroid; 2006 Mar; 16(3):211-6. PubMed ID: 16571082
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Requirement of corepressor binding of thyroid hormone receptor mutants for dominant negative inhibition.
    Nagaya T; Fujieda M; Seo H
    Biochem Biophys Res Commun; 1998 Jun; 247(3):620-3. PubMed ID: 9647743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.