203 related articles for article (PubMed ID: 9753690)
1. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy.
Renwick SB; Snell K; Baumann U
Structure; 1998 Sep; 6(9):1105-16. PubMed ID: 9753690
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
Scarsdale JN; Radaev S; Kazanina G; Schirch V; Wright HT
J Mol Biol; 2000 Feb; 296(1):155-68. PubMed ID: 10656824
[TBL] [Abstract][Full Text] [Related]
3. Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers.
Szebenyi DM; Liu X; Kriksunov IA; Stover PJ; Thiel DJ
Biochemistry; 2000 Nov; 39(44):13313-23. PubMed ID: 11063567
[TBL] [Abstract][Full Text] [Related]
4. Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.
Szebenyi DM; Musayev FN; di Salvo ML; Safo MK; Schirch V
Biochemistry; 2004 Jun; 43(22):6865-76. PubMed ID: 15170323
[TBL] [Abstract][Full Text] [Related]
5. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.
Daidone F; Florio R; Rinaldo S; Contestabile R; di Salvo ML; CutruzzolĂ F; Bossa F; Paiardini A
Eur J Med Chem; 2011 May; 46(5):1616-21. PubMed ID: 21371789
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
Trivedi V; Gupta A; Jala VR; Saravanan P; Rao GS; Rao NA; Savithri HS; Subramanya HS
J Biol Chem; 2002 May; 277(19):17161-9. PubMed ID: 11877399
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications.
Scarsdale JN; Kazanina G; Radaev S; Schirch V; Wright HT
Biochemistry; 1999 Jun; 38(26):8347-58. PubMed ID: 10387080
[TBL] [Abstract][Full Text] [Related]
8. The role of His-134, -147, and -150 residues in subunit assembly, cofactor binding, and catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
Jagath JR; Sharma B; Rao NA; Savithri HS
J Biol Chem; 1997 Sep; 272(39):24355-62. PubMed ID: 9305893
[TBL] [Abstract][Full Text] [Related]
9. Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization and comparison of recombinant zebrafish serine hydroxymethyltransferases.
Chang WN; Tsai JN; Chen BH; Huang HS; Fu TF
Drug Metab Dispos; 2007 Nov; 35(11):2127-37. PubMed ID: 17664250
[TBL] [Abstract][Full Text] [Related]
10. Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory.
Rajaram V; Bhavani BS; Kaul P; Prakash V; Appaji Rao N; Savithri HS; Murthy MR
FEBS J; 2007 Aug; 274(16):4148-60. PubMed ID: 17651438
[TBL] [Abstract][Full Text] [Related]
11. Identification of amino acid residues, essential for maintaining the tetrameric structure of sheep liver cytosolic serine hydroxymethyltransferase, by targeted mutagenesis.
Jala VR; Appaji Rao N; Savithri HS
Biochem J; 2003 Feb; 369(Pt 3):469-76. PubMed ID: 12392447
[TBL] [Abstract][Full Text] [Related]
12. Asp-89: a critical residue in maintaining the oligomeric structure of sheep liver cytosolic serine hydroxymethyltransferase.
Krishna Rao JV; Jagath JR; Sharma B; Appaji Rao N; Savithri HS
Biochem J; 1999 Oct; 343 Pt 1(Pt 1):257-63. PubMed ID: 10493937
[TBL] [Abstract][Full Text] [Related]
13. Cloning, expression, activity and folding studies of serine hydroxymethyltransferase: a target enzyme for cancer chemotherapy.
Agrawal S; Kumar A; Srivastava V; Mishra BN
J Mol Microbiol Biotechnol; 2003; 6(2):67-75. PubMed ID: 15044825
[TBL] [Abstract][Full Text] [Related]
14. Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.
Bhavani S; Trivedi V; Jala VR; Subramanya HS; Kaul P; Prakash V; Appaji Rao N; Savithri HS
Biochemistry; 2005 May; 44(18):6929-37. PubMed ID: 15865438
[TBL] [Abstract][Full Text] [Related]
15. Purification, crystallization and preliminary X-ray analysis of human recombinant cytosolic serine hydroxymethyltransferase.
Renwick SB; Skelly JV; Chave KJ; Sanders PG; Snell K; Baumann U
Acta Crystallogr D Biol Crystallogr; 1998 Sep; 54(Pt 5):1030-1. PubMed ID: 9757129
[TBL] [Abstract][Full Text] [Related]
16. Catalytic and ligand-binding characteristics of Plasmodium falciparum serine hydroxymethyltransferase.
Pang CK; Hunter JH; Gujjar R; Podutoori R; Bowman J; Mudeppa DG; Rathod PK
Mol Biochem Parasitol; 2009 Nov; 168(1):74-83. PubMed ID: 19591883
[TBL] [Abstract][Full Text] [Related]
17. The role of lysine-256 in the structure and function of sheep liver recombinant serine hydroxymethyltransferase.
Talwar R; Jagath JR; Datta A; Prakash V; Savithri HS; Rao NA
Acta Biochim Pol; 1997; 44(4):679-88. PubMed ID: 9584848
[TBL] [Abstract][Full Text] [Related]
18. Structure-function relationship in serine hydroxymethyltransferase.
Appaji Rao N; Ambili M; Jala VR; Subramanya HS; Savithri HS
Biochim Biophys Acta; 2003 Apr; 1647(1-2):24-9. PubMed ID: 12686103
[TBL] [Abstract][Full Text] [Related]
19. Importance of the amino terminus in maintenance of oligomeric structure of sheep liver cytosolic serine hydroxymethyltransferase.
Jagath JR; Sharma B; Bhaskar B; Datta A; Rao NA; Savithri HS
Eur J Biochem; 1997 Jul; 247(1):372-9. PubMed ID: 9249049
[TBL] [Abstract][Full Text] [Related]
20. Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Bhavani BS; Rajaram V; Bisht S; Kaul P; Prakash V; Murthy MR; Appaji Rao N; Savithri HS
FEBS J; 2008 Sep; 275(18):4606-19. PubMed ID: 18699779
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]