These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 9754260)

  • 1. [Strategies for identification of secretases implicated in Alzheimer's disease].
    Marambaud P; Chevallier N; Lopez-Perez E; Drouot C; Vizzanova J; Fulcrand P; Martinez J; Wilk S; Checler F
    Ann Biol Clin (Paris); 1998; 56(3):277-84. PubMed ID: 9754260
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of the multicatalytic enzyme as a possible gamma-secretase for the amyloid precursor protein.
    Mundy DI
    Biochem Biophys Res Commun; 1994 Oct; 204(1):333-41. PubMed ID: 7945379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R; Bienkowski MJ; Shuck ME; Miao H; Tory MC; Pauley AM; Brashier JR; Stratman NC; Mathews WR; Buhl AE; Carter DB; Tomasselli AG; Parodi LA; Heinrikson RL; Gurney ME
    Nature; 1999 Dec; 402(6761):533-7. PubMed ID: 10591213
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease.
    Wolfe MS; Xia W; Moore CL; Leatherwood DD; Ostaszewski B; Rahmati T; Donkor IO; Selkoe DJ
    Biochemistry; 1999 Apr; 38(15):4720-7. PubMed ID: 10200159
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a novel aspartic protease (Asp 2) as beta-secretase.
    Hussain I; Powell D; Howlett DR; Tew DG; Meek TD; Chapman C; Gloger IS; Murphy KE; Southan CD; Ryan DM; Smith TS; Simmons DL; Walsh FS; Dingwall C; Christie G
    Mol Cell Neurosci; 1999 Dec; 14(6):419-27. PubMed ID: 10656250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proprotein convertase activity contributes to the processing of the Alzheimer's beta-amyloid precursor protein in human cells: evidence for a role of the prohormone convertase PC7 in the constitutive alpha-secretase pathway.
    Lopez-Perez E; Seidah NG; Checler F
    J Neurochem; 1999 Nov; 73(5):2056-62. PubMed ID: 10537065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
    Zhou S; Zhou H; Walian PJ; Jap BK
    Proc Natl Acad Sci U S A; 2005 May; 102(21):7499-504. PubMed ID: 15890777
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA; Liu WW; Todd SA; Coulson DT; Murphy S; Irvine GB; Passmore AP
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease.
    Hook V; Toneff T; Bogyo M; Greenbaum D; Medzihradszky KF; Neveu J; Lane W; Hook G; Reisine T
    Biol Chem; 2005 Sep; 386(9):931-40. PubMed ID: 16164418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
    Flood F; Murphy S; Cowburn RF; Lannfelt L; Walker B; Johnston JA
    Biochem J; 2005 Jan; 385(Pt 2):545-50. PubMed ID: 15473868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aspartic proteases involved in Alzheimer's disease.
    Schmidt B
    Chembiochem; 2003 May; 4(5):366-78. PubMed ID: 12740808
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
    Iwatsubo T
    Rinsho Shinkeigaku; 2004 Nov; 44(11):768-70. PubMed ID: 15651286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
    Sauder JM; Arthur JW; Dunbrack RL
    J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
    Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G
    Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.
    Pollack SJ; Lewis H
    Curr Opin Investig Drugs; 2005 Jan; 6(1):35-47. PubMed ID: 15675602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S; Sunyach C; Checler F
    J Neurochem; 2006 May; 97(3):807-17. PubMed ID: 16524370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.