BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 9760286)

  • 1. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.
    Chen Y; Shen L; Zhang F; Lau SS; van Breemen RB; Nikolic D; Bolton JL
    Chem Res Toxicol; 1998 Sep; 11(9):1105-11. PubMed ID: 9760286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
    Chang M; Zhang F; Shen L; Pauss N; Alam I; van Breemen RB; Blond SY; Bolton JL
    Chem Res Toxicol; 1998 Jul; 11(7):758-65. PubMed ID: 9671538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.
    Shen L; Qiu S; Chen Y; Zhang F; van Breemen RB; Nikolic D; Bolton JL
    Chem Res Toxicol; 1998 Feb; 11(2):94-101. PubMed ID: 9511900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
    Zhang F; Chen Y; Pisha E; Shen L; Xiong Y; van Breemen RB; Bolton JL
    Chem Res Toxicol; 1999 Feb; 12(2):204-13. PubMed ID: 10027800
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
    Pisha E; Lui X; Constantinou AI; Bolton JL
    Chem Res Toxicol; 2001 Jan; 14(1):82-90. PubMed ID: 11170511
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin.
    Kolbanovskiy A; Kuzmin V; Shastry A; Kolbanovskaya M; Chen D; Chang M; Bolton JL; Geacintov NE
    Chem Res Toxicol; 2005 Nov; 18(11):1737-47. PubMed ID: 16300383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Wang Z; Chandrasena ER; Yuan Y; Peng KW; van Breemen RB; Thatcher GR; Bolton JL
    Chem Res Toxicol; 2010 Aug; 23(8):1365-73. PubMed ID: 20509668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chen Y; Liu X; Pisha E; Constantinou AI; Hua Y; Shen L; van Breemen RB; Elguindi EC; Blond SY; Zhang F; Bolton JL
    Chem Res Toxicol; 2000 May; 13(5):342-50. PubMed ID: 10813650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases.
    Zhang F; Swanson SM; van Breemen RB; Liu X; Yang Y; Gu C; Bolton JL
    Chem Res Toxicol; 2001 Dec; 14(12):1654-9. PubMed ID: 11743748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.
    Yao J; Li Y; Chang M; Wu H; Yang X; Goodman JE; Liu X; Liu H; Mesecar AD; Van Breemen RB; Yager JD; Bolton JL
    Chem Res Toxicol; 2003 May; 16(5):668-75. PubMed ID: 12755597
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin.
    Li Y; Yao J; Chang M; Cuendet M; Bolton JL
    Toxicol Lett; 2004 Dec; 154(3):225-33. PubMed ID: 15501614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.
    Cuendet M; Liu X; Pisha E; Li Y; Yao J; Yu L; Bolton JL
    Mutat Res; 2004 Jun; 550(1-2):109-21. PubMed ID: 15135645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
    Liu X; Yao J; Pisha E; Yang Y; Hua Y; van Breemen RB; Bolton JL
    Chem Res Toxicol; 2002 Apr; 15(4):512-9. PubMed ID: 11952337
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-semiquinone anion radicals,
    Flowers L; Ohnishi ST; Penning TM
    Biochemistry; 1997 Jul; 36(28):8640-8. PubMed ID: 9214311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
    Liu X; Zhang F; Liu H; Burdette JE; Li Y; Overk CR; Pisha E; Yao J; van Breemen RB; Swanson SM; Bolton JL
    Chem Res Toxicol; 2003 Jun; 16(6):741-9. PubMed ID: 12807357
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.
    Shen L; Pisha E; Huang Z; Pezzuto JM; Krol E; Alam Z; van Breemen RB; Bolton JL
    Carcinogenesis; 1997 May; 18(5):1093-101. PubMed ID: 9163701
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.
    Chang M; Shin YG; van Breemen RB; Blond SY; Bolton JL
    Biochemistry; 2001 Apr; 40(15):4811-20. PubMed ID: 11294649
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Release of iron from ferritin storage by redox cycling of stilbene and steroid estrogen metabolites: a mechanism of induction of free radical damage by estrogen.
    Wyllie S; Liehr JG
    Arch Biochem Biophys; 1997 Oct; 346(2):180-6. PubMed ID: 9343364
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus.
    Wang Z; Wijewickrama GT; Peng KW; Dietz BM; Yuan L; van Breemen RB; Bolton JL; Thatcher GR
    J Biol Chem; 2009 Mar; 284(13):8633-42. PubMed ID: 19158089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Translesion synthesis past equine estrogen-derived 2'-deoxycytidine DNA adducts by human DNA polymerases eta and kappa.
    Suzuki N; Yasui M; Santosh Laxmi YR; Ohmori H; Hanaoka F; Shibutani S
    Biochemistry; 2004 Sep; 43(35):11312-20. PubMed ID: 15366941
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.