276 related articles for article (PubMed ID: 9765459)
1. The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth.
Smith CC; Peng T; Kulka M; Aurelian L
J Virol; 1998 Nov; 72(11):9131-41. PubMed ID: 9765459
[TBL] [Abstract][Full Text] [Related]
2. Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth.
Smith CC; Nelson J; Aurelian L; Gober M; Goswami BB
J Virol; 2000 Nov; 74(22):10417-29. PubMed ID: 11044086
[TBL] [Abstract][Full Text] [Related]
3. Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10).
Aurelian L; Kokuba H; Smith CC
Vaccine; 1999 Apr; 17(15-16):1951-63. PubMed ID: 10217594
[TBL] [Abstract][Full Text] [Related]
4. The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2.
Peng T; Hunter JR; Nelson JW
Virology; 1996 Feb; 216(1):184-96. PubMed ID: 8614985
[TBL] [Abstract][Full Text] [Related]
5. A growth and latency compromised herpes simplex virus type 2 mutant (ICP10DeltaPK) has prophylactic and therapeutic protective activity in guinea pigs.
Wachsman M; Kulka M; Smith CC; Aurelian L
Vaccine; 2001 Feb; 19(15-16):1879-90. PubMed ID: 11228357
[TBL] [Abstract][Full Text] [Related]
6. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway.
Perkins D; Pereira EF; Gober M; Yarowsky PJ; Aurelian L
J Virol; 2002 Feb; 76(3):1435-49. PubMed ID: 11773417
[TBL] [Abstract][Full Text] [Related]
7. Herpes simplex virus type 2 growth and latency reactivation by cocultivation are inhibited with antisense oligonucleotides complementary to the translation initiation site of the large subunit of ribonucleotide reductase (RR1).
Aurelian L; Smith CC
Antisense Nucleic Acid Drug Dev; 2000 Apr; 10(2):77-85. PubMed ID: 10805158
[TBL] [Abstract][Full Text] [Related]
8. The transmembrane domain of the large subunit of HSV-2 ribonucleotide reductase (ICP10) is required for protein kinase activity and transformation-related signaling pathways that result in ras activation.
Smith CC; Luo JH; Hunter JC; Ordonez JV; Aurelian L
Virology; 1994 May; 200(2):598-612. PubMed ID: 8178446
[TBL] [Abstract][Full Text] [Related]
9. The large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is associated with the virion tegument and has PK activity.
Smith CC; Aurelian L
Virology; 1997 Aug; 234(2):235-42. PubMed ID: 9268154
[TBL] [Abstract][Full Text] [Related]
10. The 140-kDa RR1 protein from both HSV-1 and HSV-2 contains an intrinsic protein kinase activity capable of autophosphorylation but it is transphosphorylation defective.
Ali MA
Virology; 1995 Mar; 207(2):409-16. PubMed ID: 7886945
[TBL] [Abstract][Full Text] [Related]
11. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1.
Perkins D; Pereira EF; Aurelian L
J Virol; 2003 Jan; 77(2):1292-305. PubMed ID: 12502846
[TBL] [Abstract][Full Text] [Related]
12. A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus.
Fu X; Tao L; Cai R; Prigge J; Zhang X
Mol Ther; 2006 May; 13(5):882-90. PubMed ID: 16569513
[TBL] [Abstract][Full Text] [Related]
13. AP-1 cis-response elements are involved in basal expression and Vmw110 transactivation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).
Zhu J; Aurelian L
Virology; 1997 May; 231(2):301-12. PubMed ID: 9168892
[TBL] [Abstract][Full Text] [Related]
14. The protein kinase activity of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) fused to the extracellular domain of the epidermal growth factor receptor is ligand-inducible.
Smith CC; Luo JH; Aurelian L
Virology; 1996 Mar; 217(2):425-34. PubMed ID: 8610433
[TBL] [Abstract][Full Text] [Related]
15. The ribonucleotide reductase domain of the R1 subunit of herpes simplex virus type 2 ribonucleotide reductase is essential for R1 antiapoptotic function.
Chabaud S; Sasseville AM; Elahi SM; Caron A; Dufour F; Massie B; Langelier Y
J Gen Virol; 2007 Feb; 88(Pt 2):384-394. PubMed ID: 17251554
[TBL] [Abstract][Full Text] [Related]
16. Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10).
Chung TD; Wymer JP; Smith CC; Kulka M; Aurelian L
J Virol; 1989 Aug; 63(8):3389-98. PubMed ID: 2545912
[TBL] [Abstract][Full Text] [Related]
17. Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.
Wu N; Watkins SC; Schaffer PA; DeLuca NA
J Virol; 1996 Sep; 70(9):6358-69. PubMed ID: 8709264
[TBL] [Abstract][Full Text] [Related]
18. The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection.
Desai P; Ramakrishnan R; Lin ZW; Osak B; Glorioso JC; Levine M
J Virol; 1993 Oct; 67(10):6125-35. PubMed ID: 8396674
[TBL] [Abstract][Full Text] [Related]
19. A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.
Smith CC; Yu YX; Kulka M; Aurelian L
J Biol Chem; 2000 Aug; 275(33):25690-9. PubMed ID: 10833516
[TBL] [Abstract][Full Text] [Related]
20. ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10).
Nelson JW; Zhu J; Smith CC; Kulka M; Aurelian L
J Biol Chem; 1996 Jul; 271(29):17021-7. PubMed ID: 8663276
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
