333 related articles for article (PubMed ID: 9767632)
21. Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.
Grobler JA; Stillmock K; Hu B; Witmer M; Felock P; Espeseth AS; Wolfe A; Egbertson M; Bourgeois M; Melamed J; Wai JS; Young S; Vacca J; Hazuda DJ
Proc Natl Acad Sci U S A; 2002 May; 99(10):6661-6. PubMed ID: 11997448
[TBL] [Abstract][Full Text] [Related]
22. Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
Ranise A; Spallarossa A; Cesarini S; Bondavalli F; Schenone S; Bruno O; Menozzi G; Fossa P; Mosti L; La Colla M; Sanna G; Murreddu M; Collu G; Busonera B; Marongiu ME; Pani A; La Colla P; Loddo R
J Med Chem; 2005 Jun; 48(11):3858-73. PubMed ID: 15916438
[TBL] [Abstract][Full Text] [Related]
23. Design, synthesis, and biological evaluation of chicoric acid analogs as inhibitors of HIV-1 integrase.
Charvat TT; Lee DJ; Robinson WE; Chamberlin AR
Bioorg Med Chem; 2006 Jul; 14(13):4552-67. PubMed ID: 16524737
[TBL] [Abstract][Full Text] [Related]
24. Symmetrical 1-pyrrolidineacetamide showing anti-HIV activity through a new binding site on HIV-1 integrase.
Du L; Zhao YX; Yang LM; Zheng YT; Tang Y; Shen X; Jiang HL
Acta Pharmacol Sin; 2008 Oct; 29(10):1261-7. PubMed ID: 18817633
[TBL] [Abstract][Full Text] [Related]
25. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
26. Newer tetracycline derivatives: synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase.
Sriram D; Yogeeswari P; Senchani G; Banerjee D
Bioorg Med Chem Lett; 2007 Apr; 17(8):2372-5. PubMed ID: 17376679
[TBL] [Abstract][Full Text] [Related]
27. Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.
Melamed JY; Egbertson MS; Varga S; Vacca JP; Moyer G; Gabryelski L; Felock PJ; Stillmock KA; Witmer MV; Schleif W; Hazuda DJ; Leonard Y; Jin L; Ellis JD; Young SD
Bioorg Med Chem Lett; 2008 Oct; 18(19):5307-10. PubMed ID: 18774711
[TBL] [Abstract][Full Text] [Related]
28. Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.
Velázquez S; Chamorro C; Pérez-Pérez MJ; Alvarez R; Jimeno ML; Martín-Domenech A; Pérez C; Gago F; De Clercq E; Balzarini J; San-Félix A; Camarasa MJ
J Med Chem; 1998 Nov; 41(23):4636-47. PubMed ID: 9804703
[TBL] [Abstract][Full Text] [Related]
29. Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.
Mazumder A; Neamati N; Sunder S; Schulz J; Pertz H; Eich E; Pommier Y
J Med Chem; 1997 Sep; 40(19):3057-63. PubMed ID: 9301668
[TBL] [Abstract][Full Text] [Related]
30. A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.
Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8420-9. PubMed ID: 17005407
[TBL] [Abstract][Full Text] [Related]
31. Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Wang P; Liu C; Sanches T; Zhong Y; Liu B; Xiong J; Neamati N; Zhao G
Bioorg Med Chem Lett; 2009 Aug; 19(16):4574-8. PubMed ID: 19625188
[TBL] [Abstract][Full Text] [Related]
32. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
[TBL] [Abstract][Full Text] [Related]
33. Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase.
Long YQ; Jiang XH; Dayam R; Sanchez T; Shoemaker R; Sei S; Neamati N
J Med Chem; 2004 May; 47(10):2561-73. PubMed ID: 15115398
[TBL] [Abstract][Full Text] [Related]
34. New HIV-1 replication inhibitors of the styryquinoline class bearing aroyl/acyl groups at the C-7 position: synthesis and biological activity.
Normand-Bayle M; Bénard C; Zouhiri F; Mouscadet JF; Leh H; Thomas CM; Mbemba G; Desmaële D; d'Angelo J
Bioorg Med Chem Lett; 2005 Sep; 15(18):4019-22. PubMed ID: 16002283
[TBL] [Abstract][Full Text] [Related]
35. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Mai A; Artico M; Ragno R; Sbardella G; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; Maga G; La Colla P
Bioorg Med Chem; 2005 Mar; 13(6):2065-77. PubMed ID: 15727860
[TBL] [Abstract][Full Text] [Related]
36. Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.
Rajamaki S; Innitzer A; Falciani C; Tintori C; Christ F; Witvrouw M; Debyser Z; Massa S; Botta M
Bioorg Med Chem Lett; 2009 Jul; 19(13):3615-8. PubMed ID: 19447621
[TBL] [Abstract][Full Text] [Related]
37. Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones.
He Y; Chen F; Yu X; Wang Y; De Clercq E; Balzarini J; Pannecouque C
Bioorg Chem; 2004 Dec; 32(6):536-48. PubMed ID: 15530994
[TBL] [Abstract][Full Text] [Related]
38. Hydrazide-containing inhibitors of HIV-1 integrase.
Zhao H; Neamati N; Sunder S; Hong H; Wang S; Milne GW; Pommier Y; Burke TR
J Med Chem; 1997 Mar; 40(6):937-41. PubMed ID: 9083482
[TBL] [Abstract][Full Text] [Related]
39. Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
Langford HM; Williams PD; Homnick CF; Vacca JP; Felock PJ; Stillmock KA; Witmer MV; Hazuda DJ; Gabryelski LJ; Schleif WA
Bioorg Med Chem Lett; 2008 Jan; 18(2):721-5. PubMed ID: 18078751
[TBL] [Abstract][Full Text] [Related]
40. 4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.
Benjahad A; Croisy M; Monneret C; Bisagni E; Mabire D; Coupa S; Poncelet A; Csoka I; Guillemont J; Meyer C; Andries K; Pauwels R; de Béthune MP; Himmel DM; Das K; Arnold E; Nguyen CH; Grierson DS
J Med Chem; 2005 Mar; 48(6):1948-64. PubMed ID: 15771439
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]