449 related articles for article (PubMed ID: 9776311)
1. Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3.
Lang DH; Yeung CK; Peter RM; Ibarra C; Gasser R; Itagaki K; Philpot RM; Rettie AE
Biochem Pharmacol; 1998 Oct; 56(8):1005-12. PubMed ID: 9776311
[TBL] [Abstract][Full Text] [Related]
2. Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli.
Rettie AE; Lawton MP; Sadeque AJ; Meier GP; Philpot RM
Arch Biochem Biophys; 1994 Jun; 311(2):369-77. PubMed ID: 8203899
[TBL] [Abstract][Full Text] [Related]
3. Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.
Störmer E; Roots I; Brockmöller J
Br J Clin Pharmacol; 2000 Dec; 50(6):553-61. PubMed ID: 11136294
[TBL] [Abstract][Full Text] [Related]
4. In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
Lang DH; Rettie AE
Br J Clin Pharmacol; 2000 Oct; 50(4):311-4. PubMed ID: 11012553
[TBL] [Abstract][Full Text] [Related]
5. Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases. Comparison of human liver and kidney microsomes and mammalian enzymes.
Hamman MA; Haehner-Daniels BD; Wrighton SA; Rettie AE; Hall SD
Biochem Pharmacol; 2000 Jul; 60(1):7-17. PubMed ID: 10807940
[TBL] [Abstract][Full Text] [Related]
6. Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk.
Zhu W; Buffa JA; Wang Z; Warrier M; Schugar R; Shih DM; Gupta N; Gregory JC; Org E; Fu X; Li L; DiDonato JA; Lusis AJ; Brown JM; Hazen SL
J Thromb Haemost; 2018 Sep; 16(9):1857-1872. PubMed ID: 29981269
[TBL] [Abstract][Full Text] [Related]
7. Flavin-containing monooxygenase (FMO)-dependent metabolism of methionine and evidence for FMO3 being the major FMO involved in methionine sulfoxidation in rabbit liver and kidney microsomes.
Duescher RJ; Lawton MP; Philpot RM; Elfarra AA
J Biol Chem; 1994 Jul; 269(26):17525-30. PubMed ID: 8021260
[TBL] [Abstract][Full Text] [Related]
8. Roles of FMO and CYP450 in the metabolism in human liver microsomes of S-methyl-N,N-diethyldithiocarbamate, a disulfiram metabolite.
Pike MG; Martin YN; Mays DC; Benson LM; Naylor S; Lipsky JJ
Alcohol Clin Exp Res; 1999 Jul; 23(7):1173-9. PubMed ID: 10443982
[TBL] [Abstract][Full Text] [Related]
9. Trimethylamine N-oxygenation and N-demethylation in rat liver microsomes.
Gut I; Conney AH
Biochem Pharmacol; 1993 Jul; 46(2):239-44. PubMed ID: 8347145
[TBL] [Abstract][Full Text] [Related]
10. Dietary phenolics and their microbial metabolites are poor inhibitors of trimethylamine oxidation to trimethylamine N-oxide by hepatic flavin monooxygenase 3.
Iglesias-Carres L; Chadwick-Corbin SA; Sweet MG; Neilson AP
J Nutr Biochem; 2023 Oct; 120():109428. PubMed ID: 37549832
[TBL] [Abstract][Full Text] [Related]
11. Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.
Siddens LK; Henderson MC; Vandyke JE; Williams DE; Krueger SK
Biochem Pharmacol; 2008 Jan; 75(2):570-9. PubMed ID: 17942081
[TBL] [Abstract][Full Text] [Related]
12. Detoxification of Trimethylamine N-Oxide by the Mitochondrial Amidoxime Reducing Component mARC.
Schneider J; Girreser U; Havemeyer A; Bittner F; Clement B
Chem Res Toxicol; 2018 Jun; 31(6):447-453. PubMed ID: 29856598
[TBL] [Abstract][Full Text] [Related]
13. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
Taniguchi-Takizawa T; Shimizu M; Kume T; Yamazaki H
Drug Metab Pharmacokinet; 2015 Feb; 30(1):64-9. PubMed ID: 25760531
[TBL] [Abstract][Full Text] [Related]
14. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
Chung WG; Park CS; Roh HK; Lee WK; Cha YN
Jpn J Pharmacol; 2000 Oct; 84(2):213-20. PubMed ID: 11128045
[TBL] [Abstract][Full Text] [Related]
15. Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood.
Shimizu M; Denton T; Kozono M; Cashman JR; Leeder JS; Yamazaki H
Br J Clin Pharmacol; 2011 Apr; 71(4):585-91. PubMed ID: 21395651
[TBL] [Abstract][Full Text] [Related]
16. Prochiral sulfides as in vitro probes for multiple forms of the flavin-containing monooxygenase.
Rettie AE; Meier GP; Sadeque AJ
Chem Biol Interact; 1995 Apr; 96(1):3-15. PubMed ID: 7720102
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes.
Pike MG; Mays DC; Macomber DW; Lipsky JJ
Drug Metab Dispos; 2001 Feb; 29(2):127-32. PubMed ID: 11159801
[TBL] [Abstract][Full Text] [Related]
18. Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3).
Shimizu M; Uno Y; Utoh M; Yamazaki H
Drug Metab Pharmacokinet; 2020 Dec; 35(6):571-573. PubMed ID: 32967780
[TBL] [Abstract][Full Text] [Related]
19. Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
Petriello MC; Hoffman JB; Sunkara M; Wahlang B; Perkins JT; Morris AJ; Hennig B
J Nutr Biochem; 2016 Jul; 33():145-53. PubMed ID: 27155921
[TBL] [Abstract][Full Text] [Related]
20.
Shimizu M; Makiguchi M; Uno Y; Yamazaki H
Drug Metab Dispos; 2024 May; ():. PubMed ID: 38769015
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
