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2. Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway. Waldmann H; Karaguni IM; Carpintero M; Gourzoulidou E; Herrmann C; Brockmann C; Oschkinat H; Müller O Angew Chem Int Ed Engl; 2004 Jan; 43(4):454-8. PubMed ID: 14735533 [No Abstract] [Full Text] [Related]
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4. The new sulindac derivative IND 12 reverses Ras-induced cell transformation. Karaguni IM; Herter P; Debruyne P; Chtarbova S; Kasprzynski A; Herbrand U; Ahmadian MR; Glüsenkamp KH; Winde G; Mareel M; Möröy T; Müller O Cancer Res; 2002 Mar; 62(6):1718-23. PubMed ID: 11912145 [TBL] [Abstract][Full Text] [Related]
5. Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Zhang XF; Settleman J; Kyriakis JM; Takeuchi-Suzuki E; Elledge SJ; Marshall MS; Bruder JT; Rapp UR; Avruch J Nature; 1993 Jul; 364(6435):308-13. PubMed ID: 8332187 [TBL] [Abstract][Full Text] [Related]
6. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Piazza GA; Rahm AL; Krutzsch M; Sperl G; Paranka NS; Gross PH; Brendel K; Burt RW; Alberts DS; Pamukcu R Cancer Res; 1995 Jul; 55(14):3110-6. PubMed ID: 7606732 [TBL] [Abstract][Full Text] [Related]
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8. How does p21ras transform cells? Marshall CJ Trends Genet; 1991 Mar; 7(3):91-5. PubMed ID: 2031288 [TBL] [Abstract][Full Text] [Related]
9. Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine. Lawson KR; Ignatenko NA; Piazza GA; Cui H; Gerner EW Cancer Epidemiol Biomarkers Prev; 2000 Nov; 9(11):1155-62. PubMed ID: 11097222 [TBL] [Abstract][Full Text] [Related]
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13. Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites. Rice PL; Goldberg RJ; Ray EC; Driggers LJ; Ahnen DJ Cancer Res; 2001 Feb; 61(4):1541-7. PubMed ID: 11245463 [TBL] [Abstract][Full Text] [Related]
15. Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells. Huang Y; He Q; Hillman MJ; Rong R; Sheikh MS Cancer Res; 2001 Sep; 61(18):6918-24. PubMed ID: 11559570 [TBL] [Abstract][Full Text] [Related]
17. Sulfone metabolite of sulindac inhibits mammary carcinogenesis. Thompson HJ; Jiang C; Lu J; Mehta RG; Piazza GA; Paranka NS; Pamukcu R; Ahnen DJ Cancer Res; 1997 Jan; 57(2):267-71. PubMed ID: 9000566 [TBL] [Abstract][Full Text] [Related]
18. Ras-interacting domain of Ral GDP dissociation stimulator like (RGL) reverses v-Ras-induced transformation and Raf-1 activation in NIH3T3 cells. Okazaki M; Kishida S; Murai H; Hinoi T; Kikuchi A Cancer Res; 1996 May; 56(10):2387-92. PubMed ID: 8625316 [TBL] [Abstract][Full Text] [Related]
19. Induction of apoptosis by sulindac sulfide in HL60 cells is enhanced by p21CiP1 or p27KiP1. Ikui AE; Yao Y; Zhou P; Weinstein IB Anticancer Res; 2001; 21(4A):2297-303. PubMed ID: 11724286 [TBL] [Abstract][Full Text] [Related]
20. Mechanisms of sulindac-induced apoptosis and cell cycle arrest. Jung B; Barbier V; Brickner H; Welsh J; Fotedar A; McClelland M Cancer Lett; 2005 Feb; 219(1):15-25. PubMed ID: 15694660 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]