BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 9780001)

  • 1. p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents.
    Grombacher T; Eichhorn U; Kaina B
    Oncogene; 1998 Aug; 17(7):845-51. PubMed ID: 9780001
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
    Srivenugopal KS; Shou J; Mullapudi SR; Lang FF; Rao JS; Ali-Osman F
    Clin Cancer Res; 2001 May; 7(5):1398-409. PubMed ID: 11350911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.
    Blough MD; Zlatescu MC; Cairncross JG
    Cancer Res; 2007 Jan; 67(2):580-4. PubMed ID: 17234766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wild-type p53 suppresses transcription of the human O6-methylguanine-DNA methyltransferase gene.
    Harris LC; Remack JS; Houghton PJ; Brent TP
    Cancer Res; 1996 May; 56(9):2029-32. PubMed ID: 8616846
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of expression of the DNA repair gene O6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling.
    Boldogh I; Ramana CV; Chen Z; Biswas T; Hazra TK; Grösch S; Grombacher T; Mitra S; Kaina B
    Cancer Res; 1998 Sep; 58(17):3950-6. PubMed ID: 9731508
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
    Esteller M; Risques RA; Toyota M; Capella G; Moreno V; Peinado MA; Baylin SB; Herman JG
    Cancer Res; 2001 Jun; 61(12):4689-92. PubMed ID: 11406538
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
    Lai JC; Cheng YW; Goan YG; Chang JT; Wu TC; Chen CY; Lee H
    DNA Repair (Amst); 2008 Aug; 7(8):1352-63. PubMed ID: 18555750
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells.
    Harris LC; Potter PM; Remack JS; Brent TP
    Cancer Res; 1992 Nov; 52(22):6404-6. PubMed ID: 1423289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.
    Hermes M; Geisler H; Osswald H; Riehle R; Kloor D
    Biochem Pharmacol; 2008 Jun; 75(11):2100-11. PubMed ID: 18395186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase.
    Lavon I; Fuchs D; Zrihan D; Efroni G; Zelikovitch B; Fellig Y; Siegal T
    Cancer Res; 2007 Sep; 67(18):8952-9. PubMed ID: 17875738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma.
    Zhang L; Lu W; Miao X; Xing D; Tan W; Lin D
    Carcinogenesis; 2003 Jun; 24(6):1039-44. PubMed ID: 12807758
    [TBL] [Abstract][Full Text] [Related]  

  • 13. O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
    Wolf P; Hu YC; Doffek K; Sidransky D; Ahrendt SA
    Cancer Res; 2001 Nov; 61(22):8113-7. PubMed ID: 11719438
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts.
    von Wronski MA; Harris LC; Tano K; Mitra S; Bigner DD; Brent TP
    Oncol Res; 1992; 4(4-5):167-74. PubMed ID: 1504376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status.
    Wu JY; Wang J; Lai JC; Cheng YW; Yeh KT; Wu TC; Chen CY; Lee H
    Ann Surg Oncol; 2008 Nov; 15(11):3272-7. PubMed ID: 18712569
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors.
    Yin D; Xie D; Hofmann WK; Zhang W; Asotra K; Wong R; Black KL; Koeffler HP
    Mol Carcinog; 2003 Jan; 36(1):23-31. PubMed ID: 12503076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent.
    Ochs K; Kaina B
    Cancer Res; 2000 Oct; 60(20):5815-24. PubMed ID: 11059778
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53.
    Wang Q; Beck WT
    Cancer Res; 1998 Dec; 58(24):5762-9. PubMed ID: 9865734
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
    Sato K; Kitajima Y; Nakagawachi T; Soejima H; Miyoshi A; Koga Y; Miyazaki K
    Oncol Rep; 2005 May; 13(5):899-906. PubMed ID: 15809756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.