196 related articles for article (PubMed ID: 9780228)
1. The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.
Motamedi H; Shafiee A
Eur J Biochem; 1998 Sep; 256(3):528-34. PubMed ID: 9780228
[TBL] [Abstract][Full Text] [Related]
2. The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.
Wu K; Chung L; Revill WP; Katz L; Reeves CD
Gene; 2000 Jun; 251(1):81-90. PubMed ID: 10863099
[TBL] [Abstract][Full Text] [Related]
3. Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506.
Motamedi H; Cai SJ; Shafiee A; Elliston KO
Eur J Biochem; 1997 Feb; 244(1):74-80. PubMed ID: 9063448
[TBL] [Abstract][Full Text] [Related]
4. Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme.
Gatto GJ; McLoughlin SM; Kelleher NL; Walsh CT
Biochemistry; 2005 Apr; 44(16):5993-6002. PubMed ID: 15835888
[TBL] [Abstract][Full Text] [Related]
5. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
Tang L; Yoon YJ; Choi CY; Hutchinson CR
Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
[TBL] [Abstract][Full Text] [Related]
6. Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases.
Ikeda H; Nonomiya T; Omura S
J Ind Microbiol Biotechnol; 2001 Sep; 27(3):170-6. PubMed ID: 11780788
[TBL] [Abstract][Full Text] [Related]
7. Origin of the allyl group in FK506 biosynthesis.
Goranovic D; Kosec G; Mrak P; Fujs S; Horvat J; Kuscer E; Kopitar G; Petkovic H
J Biol Chem; 2010 May; 285(19):14292-300. PubMed ID: 20194504
[TBL] [Abstract][Full Text] [Related]
8. Biosynthesis of ansatrienin (mycotrienin) and naphthomycin. Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892.
Chen S; von Bamberg D; Hale V; Breuer M; Hardt B; Müller R; Floss HG; Reynolds KA; Leistner E
Eur J Biochem; 1999 Apr; 261(1):98-107. PubMed ID: 10103039
[TBL] [Abstract][Full Text] [Related]
9. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
Florova G; Kazanina G; Reynolds KA
Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
[TBL] [Abstract][Full Text] [Related]
10. Characterization of methyltransferase and hydroxylase genes involved in the biosynthesis of the immunosuppressants FK506 and FK520.
Motamedi H; Shafiee A; Cai SJ; Streicher SL; Arison BH; Miller RR
J Bacteriol; 1996 Sep; 178(17):5243-8. PubMed ID: 8752344
[TBL] [Abstract][Full Text] [Related]
11. The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.
Aparicio JF; Colina AJ; Ceballos E; Martín JF
J Biol Chem; 1999 Apr; 274(15):10133-9. PubMed ID: 10187796
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
Chen S; Xue Y; Sherman DH; Reynolds KA
Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
[TBL] [Abstract][Full Text] [Related]
13. The product of dpsC confers starter unit fidelity upon the daunorubicin polyketide synthase of Streptomyces sp. strain C5.
Rajgarhia VB; Priestley ND; Strohl WR
Metab Eng; 2001 Jan; 3(1):49-63. PubMed ID: 11162232
[TBL] [Abstract][Full Text] [Related]
14. Streptomyces chrysomallus FKBP-33 is a novel immunophilin consisting of two FK506 binding domains; its gene is transcriptionally coupled to the FKBP-12 gene.
Pahl A; Keller U
EMBO J; 1994 Aug; 13(15):3472-80. PubMed ID: 8062824
[TBL] [Abstract][Full Text] [Related]
15. Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.
Mo S; Kim DH; Lee JH; Park JW; Basnet DB; Ban YH; Yoo YJ; Chen SW; Park SR; Choi EA; Kim E; Jin YY; Lee SK; Park JY; Liu Y; Lee MO; Lee KS; Kim SJ; Kim D; Park BC; Lee SG; Kwon HJ; Suh JW; Moore BS; Lim SK; Yoon YJ
J Am Chem Soc; 2011 Feb; 133(4):976-85. PubMed ID: 21175203
[TBL] [Abstract][Full Text] [Related]
16. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
Tang Y; Lee TS; Kobayashi S; Khosla C
Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
[TBL] [Abstract][Full Text] [Related]
17. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.
Ikeda H; Nonomiya T; Usami M; Ohta T; Omura S
Proc Natl Acad Sci U S A; 1999 Aug; 96(17):9509-14. PubMed ID: 10449723
[TBL] [Abstract][Full Text] [Related]
18. Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering.
Lechner A; Wilson MC; Ban YH; Hwang JY; Yoon YJ; Moore BS
ACS Synth Biol; 2013 Jul; 2(7):379-83. PubMed ID: 23654255
[TBL] [Abstract][Full Text] [Related]
19. A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain.
Ruan X; Stassi D; Lax SA; Katz L
Gene; 1997 Dec; 203(1):1-9. PubMed ID: 9426000
[TBL] [Abstract][Full Text] [Related]
20. Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis.
Blažič M; Kosec G; Baebler Š; Gruden K; Petković H
Microb Cell Fact; 2015 Oct; 14():164. PubMed ID: 26466669
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]