BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 9787110)

  • 1. Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects.
    Majer M; Popov KM; Harris RA; Bogardus C; Prochazka M
    Mol Genet Metab; 1998 Oct; 65(2):181-6. PubMed ID: 9787110
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone.
    Holness MJ; Bulmer K; Smith ND; Sugden MC
    Biochem J; 2003 Feb; 369(Pt 3):687-95. PubMed ID: 12435272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets.
    Xu J; Han J; Epstein PN; Liu YQ
    Biochem Biophys Res Commun; 2006 Jun; 344(3):827-33. PubMed ID: 16631612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).
    Holness MJ; Bulmer K; Gibbons GF; Sugden MC
    Biochem J; 2002 Sep; 366(Pt 3):839-46. PubMed ID: 12099888
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects.
    Bandyopadhyay GK; Yu JG; Ofrecio J; Olefsky JM
    Diabetes; 2006 Aug; 55(8):2277-85. PubMed ID: 16873691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyruvate dehydrogenase activation and kinase expression in human skeletal muscle during fasting.
    Spriet LL; Tunstall RJ; Watt MJ; Mehan KA; Hargreaves M; Cameron-Smith D
    J Appl Physiol (1985); 2004 Jun; 96(6):2082-7. PubMed ID: 14966024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Therapeutic potential of the mammalian pyruvate dehydrogenase kinases in the prevention of hyperglycaemia.
    Sugden MC; Holness MJ
    Curr Drug Targets Immune Endocr Metabol Disord; 2002 Jul; 2(2):151-65. PubMed ID: 12476789
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin suppresses PDK-4 expression in skeletal muscle independently of plasma FFA.
    Lee FN; Zhang L; Zheng D; Choi WS; Youn JH
    Am J Physiol Endocrinol Metab; 2004 Jul; 287(1):E69-74. PubMed ID: 15026305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased expression of hepatic pyruvate dehydrogenase kinases 2 and 4 in young and middle-aged Otsuka Long-Evans Tokushima Fatty rats: induction by elevated levels of free fatty acids.
    Bajotto G; Murakami T; Nagasaki M; Qin B; Matsuo Y; Maeda K; Ohashi M; Oshida Y; Sato Y; Shimomura Y
    Metabolism; 2006 Mar; 55(3):317-23. PubMed ID: 16483874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduced PDK4 expression associates with increased insulin sensitivity in postobese patients.
    Rosa G; Di Rocco P; Manco M; Greco AV; Castagneto M; Vidal H; Mingrone G
    Obes Res; 2003 Feb; 11(2):176-82. PubMed ID: 12582211
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Postabsorptive respiratory quotient and insulin-stimulated glucose storage rate in nondiabetic pima indians are related To glycogen synthase fractional activity in cultured myoblasts.
    Mott DM; Pratley RE; Bogardus C
    J Clin Invest; 1998 May; 101(10):2251-6. PubMed ID: 9593781
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism.
    Vestergaard H
    Dan Med Bull; 1999 Feb; 46(1):13-34. PubMed ID: 10081651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of elevated lipid concentrations on human skeletal muscle gene expression.
    Tunstall RJ; Cameron-Smith D
    Metabolism; 2005 Jul; 54(7):952-9. PubMed ID: 15988707
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin resistance in Pima Indians. A combined effect of genetic predisposition and obesity-related skeletal muscle cell hypertrophy.
    Lillioja S; Bogardus C
    Acta Med Scand Suppl; 1988; 723():103-19. PubMed ID: 3134799
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downregulation of the skeletal muscle pyruvate dehydrogenase complex in the Otsuka Long-Evans Tokushima Fatty rat both before and after the onset of diabetes mellitus.
    Bajotto G; Murakami T; Nagasaki M; Tamura T; Tamura N; Harris RA; Shimomura Y; Sato Y
    Life Sci; 2004 Sep; 75(17):2117-30. PubMed ID: 15312755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 protein expression in starvation and after refeeding.
    Sugden MC; Bulmer K; Gibbons GF; Holness MJ
    Arch Biochem Biophys; 2001 Nov; 395(2):246-52. PubMed ID: 11697863
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular mechanisms of diabetes reversibility after bariatric surgery.
    Rosa G; Mingrone G; Manco M; Euthine V; Gniuli D; Calvani R; Calvani M; Favuzzi AM; Castagneto M; Vidal H
    Int J Obes (Lond); 2007 Sep; 31(9):1429-36. PubMed ID: 17515913
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin.
    Sugden MC; Bulmer K; Gibbons GF; Knight BL; Holness MJ
    Biochem J; 2002 Jun; 364(Pt 2):361-8. PubMed ID: 12023878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Basic disturbances in skeletal muscle fatty acid metabolism in obesity and type 2 diabetes mellitus.
    Blaak EE
    Proc Nutr Soc; 2004 May; 63(2):323-30. PubMed ID: 15294050
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retinoid X receptor expression in skeletal muscle of nondiabetic, obese and type 2 diabetic individuals.
    Codner E; Loviscach M; Ciaraldi TP; Rehman N; Carter L; Mudaliar S; Henry RR
    Metabolism; 2001 Jul; 50(7):830-4. PubMed ID: 11436190
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.