These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 9799520)

  • 1. H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate.
    Hightower KE; Huang CC; Casey PJ; Fierke CA
    Biochemistry; 1998 Nov; 37(44):15555-62. PubMed ID: 9799520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate.
    Huang CC; Casey PJ; Fierke CA
    J Biol Chem; 1997 Jan; 272(1):20-3. PubMed ID: 8995218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase.
    Hightower KE; Casey PJ; Fierke CA
    Biochemistry; 2001 Jan; 40(4):1002-10. PubMed ID: 11170422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of the zinc(II) center in protein farnesyltransferase by mutagenesis of the zinc(II) ligands.
    Harris CM; Derdowski AM; Poulter CD
    Biochemistry; 2002 Aug; 41(33):10554-62. PubMed ID: 12173942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation.
    Pickett JS; Bowers KE; Hartman HL; Fu HW; Embry AC; Casey PJ; Fierke CA
    Biochemistry; 2003 Aug; 42(32):9741-8. PubMed ID: 12911316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
    Long SB; Casey PJ; Beese LS
    Biochemistry; 1998 Jul; 37(27):9612-8. PubMed ID: 9657673
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state.
    Huang C; Hightower KE; Fierke CA
    Biochemistry; 2000 Mar; 39(10):2593-602. PubMed ID: 10704208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures.
    Long SB; Casey PJ; Beese LS
    Structure; 2000 Feb; 8(2):209-22. PubMed ID: 10673434
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.
    Troutman JM; Subramanian T; Andres DA; Spielmann HP
    Biochemistry; 2007 Oct; 46(40):11310-21. PubMed ID: 17854205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Yeast protein farnesyltransferase. pKas of peptide substrates bound as zinc thiolates.
    Rozema DB; Poulter CD
    Biochemistry; 1999 Oct; 38(40):13138-46. PubMed ID: 10529185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of metals in the reaction catalyzed by protein farnesyltransferase.
    Saderholm MJ; Hightower KE; Fierke CA
    Biochemistry; 2000 Oct; 39(40):12398-405. PubMed ID: 11015220
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.
    Subramanian T; Liu S; Troutman JM; Andres DA; Spielmann HP
    Chembiochem; 2008 Nov; 9(17):2872-82. PubMed ID: 18985644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase.
    Chehade KA; Kiegiel K; Isaacs RJ; Pickett JS; Bowers KE; Fierke CA; Andres DA; Spielmann HP
    J Am Chem Soc; 2002 Jul; 124(28):8206-19. PubMed ID: 12105898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity.
    Hartman HL; Hicks KA; Fierke CA
    Biochemistry; 2005 Nov; 44(46):15314-24. PubMed ID: 16285735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interplay of isoprenoid and peptide substrate specificity in protein farnesyltransferase.
    Reigard SA; Zahn TJ; Haworth KB; Hicks KA; Fierke CA; Gibbs RA
    Biochemistry; 2005 Aug; 44(33):11214-23. PubMed ID: 16101305
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of the carboxyterminal residue in peptide binding to protein farnesyltransferase and protein geranylgeranyltransferase.
    Roskoski R; Ritchie P
    Arch Biochem Biophys; 1998 Aug; 356(2):167-76. PubMed ID: 9705207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysine(164)alpha of protein farnesyltransferase is important for both CaaX substrate binding and catalysis.
    Hightower KE; De S; Weinbaum C; Spence RA; Casey PJ
    Biochem J; 2001 Dec; 360(Pt 3):625-31. PubMed ID: 11736652
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release.
    Furfine ES; Leban JJ; Landavazo A; Moomaw JF; Casey PJ
    Biochemistry; 1995 May; 34(20):6857-62. PubMed ID: 7756316
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Yeast protein farnesyltransferase: steady-state kinetic studies of substrate binding.
    Dolence JM; Cassidy PB; Mathis JR; Poulter CD
    Biochemistry; 1995 Dec; 34(51):16687-94. PubMed ID: 8527442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A rapid and convenient filter-binding assay for ras p21 processing enzyme farnesyltransferase.
    Khan SG; Mukhtar H; Agarwal R
    J Biochem Biophys Methods; 1995 Jun; 30(2-3):133-44. PubMed ID: 7494090
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.