These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

409 related articles for article (PubMed ID: 9804706)

  • 1. New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.
    Sicinski RR; Prahl JM; Smith CM; DeLuca HF
    J Med Chem; 1998 Nov; 41(23):4662-74. PubMed ID: 9804706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.
    Plonska-Ocypa K; Sicinski RR; Plum LA; Grzywacz P; Frelek J; Clagett-Dame M; DeLuca HF
    Bioorg Med Chem; 2009 Feb; 17(4):1747-63. PubMed ID: 19167893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel 2-alkyl-1alpha,25-dihydroxy-19-norvitamin D3: efficient synthesis with Julia olefination, evaluation of biological activity and development of new analyzing system for co-activator recruitment.
    Arai MA; Kittaka A
    Anticancer Res; 2006; 26(4A):2621-31. PubMed ID: 16886672
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New derivatives of 1alpha,25-dihydroxy-19-norvitamin D3 with two substituents at C-2: synthesis and biological activity.
    Shimizu M; Iwasaki Y; Shimazaki M; Amano Y; Yamamoto K; Reischl W; Yamada S
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1451-5. PubMed ID: 15713405
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New 2-alkylidene 1alpha,25-dihydroxy-19-norvitamin D3 analogues of high intestinal activity: synthesis and biological evaluation of 2-(3'-alkoxypropylidene) and 2-(3'-hydroxypropylidene) derivatives.
    Glebocka A; Sicinski RR; Plum LA; Clagett-Dame M; DeLuca HF
    J Med Chem; 2006 May; 49(10):2909-20. PubMed ID: 16686534
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New derivative of 1alpha,25-dihydroxy-19-norvitamin D3 with 3'-alkoxypropylidene moiety at C-2: synthesis, biological activity and conformational analysis.
    Glebocka A; Sicinski RR; DeLuca HF
    J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):25-30. PubMed ID: 15225741
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor.
    Grzywacz P; Plum LA; Sicinska W; Sicinski RR; Prahl JM; DeLuca HF
    J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):13-7. PubMed ID: 15225739
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.
    Shimazaki M; Miyamoto Y; Yamamoto K; Yamada S; Takami M; Shinki T; Udagawa N; Shimizu M
    Bioorg Med Chem; 2006 Jul; 14(13):4645-56. PubMed ID: 16513359
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.
    Ono K; Yoshida A; Saito N; Fujishima T; Honzawa S; Suhara Y; Kishimoto S; Sugiura T; Waku K; Takayama H; Kittaka A
    J Org Chem; 2003 Sep; 68(19):7407-15. PubMed ID: 12968893
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological activity of 1 alpha, 25-dihydroxy-18-norvitamin D3 and 1 alpha, 25-dihydroxy-18,19-dinorvitamin D3.
    Sicinski RR; Perlman KL; Prahl J; Smith C; DeLuca HF
    J Med Chem; 1996 Oct; 39(22):4497-506. PubMed ID: 8893845
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New 1alpha,25-dihydroxy-19-norvitamin D(3) compounds constrained in a single A-ring conformation: synthesis of the analogues by ring-closing metathesis route and their biological evaluation.
    Glebocka A; Sokolowska K; Sicinski RR; Plum LA; Deluca HF
    J Med Chem; 2009 Jun; 52(11):3496-504. PubMed ID: 19402630
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.
    Shimizu M; Miyamoto Y; Kobayashi E; Shimazaki M; Yamamoto K; Reischl W; Yamada S
    Bioorg Med Chem; 2006 Jun; 14(12):4277-94. PubMed ID: 16503143
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and Biological Activity of 2-Methylene Analogues of Calcitriol and Related Compounds.
    Sibilska IK; Szybinski M; Sicinski RR; Plum LA; DeLuca HF
    J Med Chem; 2015 Dec; 58(24):9653-62. PubMed ID: 26574921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
    Shimizu M; Miyamoto Y; Takaku H; Matsuo M; Nakabayashi M; Masuno H; Udagawa N; DeLuca HF; Ikura T; Ito N
    Bioorg Med Chem; 2008 Jul; 16(14):6949-64. PubMed ID: 18539034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D₃ (2MD): total synthesis, docking to the VDR, and biological evaluation.
    Plonska-Ocypa K; Sibilska I; Sicinski RR; Sicinska W; Plum LA; DeLuca HF
    Bioorg Med Chem; 2011 Dec; 19(23):7205-20. PubMed ID: 22018918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2-Ethyl and 2-ethylidene analogues of 1alpha,25-dihydroxy-19-norvitamin D(3): synthesis, conformational analysis, biological activities, and docking to the modeled rVDR ligand binding domain.
    Sicinski RR; Rotkiewicz P; Kolinski A; Sicinska W; Prahl JM; Smith CM; DeLuca HF
    J Med Chem; 2002 Aug; 45(16):3366-80. PubMed ID: 12139448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological activity of 2-(3'-hydroxypropylidene)-1α-hydroxy-19-norvitamin D analogues with shortened alkyl side chains.
    Glebocka A; Sicinski RR; Plum LA; Deluca HF
    J Med Chem; 2011 Oct; 54(19):6832-42. PubMed ID: 21902235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An analog of 1alpha,25-dihydroxy-19-norvitamin D3 with the 1alpha-hydroxy group fixed in the axial position lacks biological activity in vitro.
    Sicinski RR; Glebocka A; Plum LA; DeLuca HF
    J Steroid Biochem Mol Biol; 2007 Mar; 103(3-5):293-7. PubMed ID: 17223547
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methyl-introduced A-ring analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological evaluation.
    Fujishima T; Tsutsumi R; Negishi Y; Fujii S; Takayama H; Kittaka A; Kurihara M
    Anticancer Res; 2006; 26(4A):2633-6. PubMed ID: 16886673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and Biological Activity of 25-Hydroxy-2-methylene-vitamin D3 analogues monohydroxylated in the A-ring.
    Sibilska IK; Sicinski RR; Ochalek JT; Plum LA; DeLuca HF
    J Med Chem; 2014 Oct; 57(20):8319-31. PubMed ID: 25221942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.