BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1010 related articles for article (PubMed ID: 9806945)

  • 1. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
    Yamazaki H; Shimada T
    Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes.
    Yamazaki H; Shimada T
    Xenobiotica; 1998 Oct; 28(10):995-1004. PubMed ID: 9849646
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes.
    Yamazaki H; Urano T; Hiroki S; Shimada T
    J Toxicol Sci; 1996 Nov; 21(4):215-26. PubMed ID: 8959645
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes.
    Yamazaki H; Hiroki S; Urano T; Inoue K; Shimada T
    Xenobiotica; 1996 Nov; 26(11):1143-53. PubMed ID: 8948090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis.
    Wang RW; Newton DJ; Scheri TD; Lu AY
    Drug Metab Dispos; 1997 Apr; 25(4):502-7. PubMed ID: 9107550
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.
    Chiba M; Hensleigh M; Nishime JA; Balani SK; Lin JH
    Drug Metab Dispos; 1996 Mar; 24(3):307-14. PubMed ID: 8820421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro.
    Ufer M; Svensson JO; Krausz KW; Gelboin HV; Rane A; Tybring G
    Eur J Clin Pharmacol; 2004 May; 60(3):173-82. PubMed ID: 15054565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K; Konishi T; Nishikawa H; Kitamura S
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    Ball SE; Ahern D; Scatina J; Kao J
    Br J Clin Pharmacol; 1997 Jun; 43(6):619-26. PubMed ID: 9205822
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites.
    Sutton D; Butler AM; Nadin L; Murray M
    J Pharmacol Exp Ther; 1997 Jul; 282(1):294-300. PubMed ID: 9223567
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of rat liver estrogen 2/4-hydroxylase activity by troleandomycin: comparison with erythromycin and roxithromycin.
    Fisher D; Labbe G; Berson A; Tinel M; Loeper J; Larrey D; Pessayre D
    J Pharmacol Exp Ther; 1990 Sep; 254(3):1120-7. PubMed ID: 2395109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N; Oda Y; Hase I; Asada A
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes.
    Ren S; Yang JS; Kalhorn TF; Slattery JT
    Cancer Res; 1997 Oct; 57(19):4229-35. PubMed ID: 9331082
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.
    Huang Z; Guengerich FP; Kaminsky LS
    Carcinogenesis; 1998 May; 19(5):867-72. PubMed ID: 9635876
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha,7alpha,12alpha-triol in human liver microsomes.
    Furster C; Wikvall K
    Biochim Biophys Acta; 1999 Jan; 1437(1):46-52. PubMed ID: 9931427
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
    Yamazaki H; Gillam EM; Dong MS; Johnson WW; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1997 Jun; 342(2):329-37. PubMed ID: 9186495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of cytochrome P450 in the metabolism of rebamipide by the human liver.
    Koyama N; Sasabe H; Miyamoto G
    Xenobiotica; 2002 Jul; 32(7):573-86. PubMed ID: 12162853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 51.