99 related articles for article (PubMed ID: 9807160)
1. Synthesis of new bifunctional compounds which selectively alkylate guanines in DNA.
Henderson ND; Lacy SM; O'Hare CC; Hartley JA; McClean S; Wakelin LP; Kelland LR; Robins DJ
Anticancer Drug Des; 1998 Oct; 13(7):749-68. PubMed ID: 9807160
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of new homochiral bispyrrolidines as potential DNA cross-linking antitumour agents.
Anderson FM; O'Hare CC; Hartley JA; Robins DJ
Anticancer Drug Des; 2000 Apr; 15(2):119-26. PubMed ID: 10901299
[TBL] [Abstract][Full Text] [Related]
3. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
Atwell GJ; Fan JY; Tan K; Denny WA
J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of novel DNA cross-linking antitumour agents based on polyazamacrocycles.
Parker LL; Anderson FM; O'Hare CC; Lacy SM; Bingham JP; Robins DJ; Hartley JA
Bioorg Med Chem; 2005 Apr; 13(7):2389-95. PubMed ID: 15755641
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and anti-cancer activity of 2,6-disubstituted N-methylpiperidine derivatives and their N-oxides.
Henderson ND; Plumb JA; Robins DJ; Workman P
Anticancer Drug Des; 1996 Sep; 11(6):421-38. PubMed ID: 8836108
[TBL] [Abstract][Full Text] [Related]
6. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: potential for development of tumor-selective N-oxides.
Pors K; Shnyder SD; Teesdale-Spittle PH; Hartley JA; Zloh M; Searcey M; Patterson LH
J Med Chem; 2006 Nov; 49(24):7013-23. PubMed ID: 17125254
[TBL] [Abstract][Full Text] [Related]
9. Unsymmetrical DNA cross-linking agents: combination of the CBI and PBD pharmacophores.
Tercel M; Stribbling SM; Sheppard H; Siim BG; Wu K; Pullen SM; Botting KJ; Wilson WR; Denny WA
J Med Chem; 2003 May; 46(11):2132-51. PubMed ID: 12747786
[TBL] [Abstract][Full Text] [Related]
10. Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes.
Kakadiya R; Dong H; Lee PC; Kapuriya N; Zhang X; Chou TC; Lee TC; Kapuriya K; Shah A; Su TL
Bioorg Med Chem; 2009 Aug; 17(15):5614-26. PubMed ID: 19576785
[TBL] [Abstract][Full Text] [Related]
11. Adenine-containing DNA-DNA cross-links of antitumor nitrogen mustards.
Balcome S; Park S; Quirk Dorr DR; Hafner L; Phillips L; Tretyakova N
Chem Res Toxicol; 2004 Jul; 17(7):950-62. PubMed ID: 15257621
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of novel chloroethylaminoanthraquinones with potent cytotoxic activity against cisplatin-resistant tumor cells.
Pors K; Paniwnyk Z; Ruparelia KC; Teesdale-Spittle PH; Hartley JA; Kelland LR; Patterson LH
J Med Chem; 2004 Mar; 47(7):1856-9. PubMed ID: 15027879
[TBL] [Abstract][Full Text] [Related]
13. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
Smaill JB; Fan JY; Denny WA
Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
[TBL] [Abstract][Full Text] [Related]
14. Alkylating agent and chromatin structure determine sequence context-dependent formation of alkylpurines.
Cloutier JF; Castonguay A; O'Connor TR; Drouin R
J Mol Biol; 2001 Feb; 306(2):169-88. PubMed ID: 11237592
[TBL] [Abstract][Full Text] [Related]
15. Sequence-specific DNA interactions by novel alkylating anthracycline derivatives.
Marchini S; Gonzalez Paz O; Ripamonti M; Geroni C; Bargiotti A; Caruso M; Todeschi S; D'Incalci M; Broggini M
Anticancer Drug Des; 1995 Dec; 10(8):641-53. PubMed ID: 8595123
[TBL] [Abstract][Full Text] [Related]
16. Cross-linking and sequence-specific alkylation of DNA by aziridinylquinones. 3. Effects of alkyl substituents.
Hargreaves RH; O'Hare CC; Hartley JA; Ross D; Butler J
J Med Chem; 1999 Jun; 42(12):2245-50. PubMed ID: 10377230
[TBL] [Abstract][Full Text] [Related]
17. Novel nitrogen mustard-armed combi-molecules for the selective targeting of epidermal growth factor receptor overexperessing solid tumors: discovery of an unusual structure-activity relationship.
Rachid Z; Brahimi F; Qiu Q; Williams C; Hartley JM; Hartley JA; Jean-Claude BJ
J Med Chem; 2007 May; 50(11):2605-8. PubMed ID: 17472358
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, DNA binding and cytotoxicity of 1-[[omega-(9-acridinyl)amino]alkyl]carbonyl -3-(chloromethyl)-6-hydroxyindolines, a new class of DNA-targeted alkylating agents.
Fan JY; Tercel M; Denny WA
Anticancer Drug Des; 1997 Jun; 12(4):277-93. PubMed ID: 9199660
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
[TBL] [Abstract][Full Text] [Related]
20. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]