125 related articles for article (PubMed ID: 9815193)
1. Thioether adducts of a new imine reactive intermediate of the pneumotoxin 3-methylindole.
Skordos KW; Laycock JD; Yost GS
Chem Res Toxicol; 1998 Nov; 11(11):1326-31. PubMed ID: 9815193
[TBL] [Abstract][Full Text] [Related]
2. Evidence supporting the formation of 2,3-epoxy-3-methylindoline: a reactive intermediate of the pneumotoxin 3-methylindole.
Skordos KW; Skiles GL; Laycock JD; Lanza DL; Yost GS
Chem Res Toxicol; 1998 Jul; 11(7):741-9. PubMed ID: 9671536
[TBL] [Abstract][Full Text] [Related]
3. Metabolism and bioactivation of 3-methylindole by human liver microsomes.
Yan Z; Easterwood LM; Maher N; Torres R; Huebert N; Yost GS
Chem Res Toxicol; 2007 Jan; 20(1):140-8. PubMed ID: 17226936
[TBL] [Abstract][Full Text] [Related]
4. Identification of a cysteinyl adduct of oxidized 3-methylindole from goat lung and human liver microsomal proteins.
Ruangyuttikarn W; Skiles GL; Yost GS
Chem Res Toxicol; 1992; 5(5):713-9. PubMed ID: 1446013
[TBL] [Abstract][Full Text] [Related]
5. Metabolism and bioactivation of 3-methylindole by Clara cells, alveolar macrophages, and subcellular fractions from rabbit lungs.
Thornton-Manning JR; Nichols WK; Manning BW; Skiles GL; Yost GS
Toxicol Appl Pharmacol; 1993 Oct; 122(2):182-90. PubMed ID: 8212000
[TBL] [Abstract][Full Text] [Related]
6. Structure of the glutathione adduct of activated 3-methylindole indicates that an imine methide is the electrophilic intermediate.
Nocerini MR; Yost GS; Carlson JR; Liberato DJ; Breeze RG
Drug Metab Dispos; 1985; 13(6):690-4. PubMed ID: 2867872
[TBL] [Abstract][Full Text] [Related]
7. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.
Thornton-Manning J; Appleton ML; Gonzalez FJ; Yost GS
J Pharmacol Exp Ther; 1996 Jan; 276(1):21-9. PubMed ID: 8558432
[TBL] [Abstract][Full Text] [Related]
8. Mechanistic studies on the cytochrome P450-catalyzed dehydrogenation of 3-methylindole.
Skiles GL; Yost GS
Chem Res Toxicol; 1996; 9(1):291-7. PubMed ID: 8924606
[TBL] [Abstract][Full Text] [Related]
9. Identification of phase I metabolites of 3-methylindole produced by pig liver microsomes.
Diaz GJ; Skordos KW; Yost GS; Squires EJ
Drug Metab Dispos; 1999 Oct; 27(10):1150-6. PubMed ID: 10497141
[TBL] [Abstract][Full Text] [Related]
10. Detection and characterization of DNA adducts of 3-methylindole.
Regal KA; Laws GM; Yuan C; Yost GS; Skiles GL
Chem Res Toxicol; 2001 Aug; 14(8):1014-24. PubMed ID: 11511175
[TBL] [Abstract][Full Text] [Related]
11. Production and characterization of specific antibodies: utilization to predict organ- and species-selective pneumotoxicity of 3-methylindole.
Kaster JK; Yost GS
Toxicol Appl Pharmacol; 1997 Apr; 143(2):324-37. PubMed ID: 9144449
[TBL] [Abstract][Full Text] [Related]
12. Electrophilic metabolites of 3-methylindole as toxic intermediates in pulmonary oedema.
Nocerini MR; Carlson JR; Yost GS
Xenobiotica; 1984 Jul; 14(7):561-4. PubMed ID: 6506769
[TBL] [Abstract][Full Text] [Related]
13. Isolation of a mercapturate adduct produced subsequent to glutathione conjugation of bioactivated 3-methylindole.
Skiles GL; Smith DJ; Appleton ML; Carlson JR; Yost GS
Toxicol Appl Pharmacol; 1991 May; 108(3):531-7. PubMed ID: 2020974
[TBL] [Abstract][Full Text] [Related]
14. Metabolic activation of a novel 3-substituted indole-containing TNF-alpha inhibitor: dehydrogenation and inactivation of CYP3A4.
Sun H; Yost GS
Chem Res Toxicol; 2008 Feb; 21(2):374-85. PubMed ID: 18095656
[TBL] [Abstract][Full Text] [Related]
15. Identification of goat and mouse urinary metabolites of the pneumotoxin, 3-methylindole.
Smith DJ; Skiles GL; Appleton ML; Carlson JR; Yost GS
Xenobiotica; 1993 Sep; 23(9):1025-44. PubMed ID: 8291262
[TBL] [Abstract][Full Text] [Related]
16. Identification of a novel glutathione adduct of diclofenac, 4'-hydroxy-2'-glutathion-deschloro-diclofenac, upon incubation with human liver microsomes.
Yu LJ; Chen Y; Deninno MP; O'Connell TN; Hop CE
Drug Metab Dispos; 2005 Apr; 33(4):484-8. PubMed ID: 15640374
[TBL] [Abstract][Full Text] [Related]
17. Identification of beta-glucuronidase-resistant diastereomeric glucuronides of 3-hydroxy-3-methyloxindole formed during 3-methylindole metabolism in goats.
Smith DJ; Appleton ML; Carlson JR; Yost GS
Drug Metab Dispos; 1996 Jan; 24(1):119-25. PubMed ID: 8825199
[TBL] [Abstract][Full Text] [Related]
18. Decreased pneumotoxicity of deuterated 3-methylindole: bioactivation requires methyl C-H bond breakage.
Huijzer JC; Adams JD; Yost GS
Toxicol Appl Pharmacol; 1987 Aug; 90(1):60-8. PubMed ID: 3629592
[TBL] [Abstract][Full Text] [Related]
19. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
Tang W; Stearns RA; Wang RW; Chiu SH; Baillie TA
Chem Res Toxicol; 1999 Feb; 12(2):192-9. PubMed ID: 10027798
[TBL] [Abstract][Full Text] [Related]
20. Glutathione adduct formation with microsomally activated metabolites of the pulmonary alkylating and cytotoxic agent, 3-methylindole.
Nocerini MR; Carlson JR; Yost GS
Toxicol Appl Pharmacol; 1985 Oct; 81(1):75-84. PubMed ID: 4049423
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
