These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 9815960)

  • 1. Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome.
    Kuan CT; Pai LH; Pastan I
    Clin Cancer Res; 1995 Dec; 1(12):1589-94. PubMed ID: 9815960
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I; Pastan I
    Clin Cancer Res; 1995 Sep; 1(9):1023-9. PubMed ID: 9816075
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I; Pastan I
    J Biol Chem; 1995 Oct; 270(40):23373-80. PubMed ID: 7559495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.
    Bigner DD; Archer GE; McLendon RE; Friedman HS; Fuchs HE; Pai LH; Herndon JE; Pastan IH
    Clin Cancer Res; 1995 Dec; 1(12):1545-55. PubMed ID: 9815955
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Immunotoxins made with a recombinant form of Pseudomonas exotoxin A that do not require proteolysis for activity.
    Theuer CP; Kreitman RJ; FitzGerald DJ; Pastan I
    Cancer Res; 1993 Jan; 53(2):340-7. PubMed ID: 8417828
    [TBL] [Abstract][Full Text] [Related]  

  • 6. B3(Fab)-PE38M: a recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3.
    Choe M; Webber KO; Pastan I
    Cancer Res; 1994 Jul; 54(13):3460-7. PubMed ID: 8012967
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I; Padlan EA; Jung SH; Lee B; Pastan I
    Proc Natl Acad Sci U S A; 1994 Dec; 91(25):12051-5. PubMed ID: 7991583
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice.
    Benhar I; Reiter Y; Pai LH; Pastan I
    Int J Cancer; 1995 Jul; 62(3):351-5. PubMed ID: 7628878
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of caspases in immunotoxin-induced apoptosis of cancer cells.
    Keppler-Hafkemeyer A; Brinkmann U; Pastan I
    Biochemistry; 1998 Dec; 37(48):16934-42. PubMed ID: 9836586
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.
    Pai LH; Batra JK; FitzGerald DJ; Willingham MC; Pastan I
    Proc Natl Acad Sci U S A; 1991 Apr; 88(8):3358-62. PubMed ID: 2014255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome.
    Baluna R; Rizo J; Gordon BE; Ghetie V; Vitetta ES
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):3957-62. PubMed ID: 10097145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U; Lee BK; Pastan I
    J Immunol; 1993 Apr; 150(7):2774-82. PubMed ID: 8454854
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys.
    Pai LH; Batra JK; FitzGerald DJ; Willingham MC; Pastan I
    Cancer Res; 1992 Jun; 52(11):3189-93. PubMed ID: 1591729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of recombinant immunotoxins against LeY antigen expressing tumor cells: influence of affinity, size, and stability.
    Bera TK; Pastan I
    Bioconjug Chem; 1998; 9(6):736-43. PubMed ID: 9815167
    [TBL] [Abstract][Full Text] [Related]  

  • 15. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.
    Brinkmann U; Pai LH; FitzGerald DJ; Willingham M; Pastan I
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8616-20. PubMed ID: 1924323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of epitopes on a mutant form of Pseudomonas exotoxin using serum from humans treated with Pseudomonas exotoxin containing immunotoxins.
    Roscoe DM; Pai LH; Pastan I
    Eur J Immunol; 1997 Jun; 27(6):1459-68. PubMed ID: 9209499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.
    Onda M; Nagata S; Tsutsumi Y; Vincent JJ; Wang Q; Kreitman RJ; Lee B; Pastan I
    Cancer Res; 2001 Jul; 61(13):5070-7. PubMed ID: 11431343
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improved antitumor activity of a recombinant anti-Lewis(y) immunotoxin not requiring proteolytic activation.
    Kuan CT; Pastan I
    Proc Natl Acad Sci U S A; 1996 Feb; 93(3):974-8. PubMed ID: 8577771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin.
    Roscoe DM; Jung SH; Benhar I; Pai L; Lee BK; Pastan I
    Infect Immun; 1994 Nov; 62(11):5055-65. PubMed ID: 7927788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Treatment of advanced solid tumors with immunotoxin LMB-1: an antibody linked to Pseudomonas exotoxin.
    Pai LH; Wittes R; Setser A; Willingham MC; Pastan I
    Nat Med; 1996 Mar; 2(3):350-3. PubMed ID: 8612238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.