BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 9819392)

  • 1. Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation.
    Roof RW; Haskell MD; Dukes BD; Sherman N; Kinter M; Parsons SJ
    Mol Cell Biol; 1998 Dec; 18(12):7052-63. PubMed ID: 9819392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two SH2 domains of p120 Ras GTPase-activating protein bind synergistically to tyrosine phosphorylated p190 Rho GTPase-activating protein.
    Bryant SS; Briggs S; Smithgall TE; Martin GA; McCormick F; Chang JH; Parsons SJ; Jove R
    J Biol Chem; 1995 Jul; 270(30):17947-52. PubMed ID: 7629101
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors.
    Chang JH; Wilson LK; Moyers JS; Zhang K; Parsons SJ
    Oncogene; 1993 Apr; 8(4):959-67. PubMed ID: 7681161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.
    van der Geer P; Henkemeyer M; Jacks T; Pawson T
    Mol Cell Biol; 1997 Apr; 17(4):1840-7. PubMed ID: 9121432
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation.
    Chang JH; Gill S; Settleman J; Parsons SJ
    J Cell Biol; 1995 Jul; 130(2):355-68. PubMed ID: 7542246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein tyrosine phosphatase PTP20 induces actin cytoskeleton reorganization by dephosphorylating p190 RhoGAP in rat ovarian granulosa cells stimulated with follicle-stimulating hormone.
    Shiota M; Tanihiro T; Nakagawa Y; Aoki N; Ishida N; Miyazaki K; Ullrich A; Miyazaki H
    Mol Endocrinol; 2003 Apr; 17(4):534-49. PubMed ID: 12554790
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Changes in tyrosine-phosphorylated p190 and its association with p120 type I and p100 type II rasGAPs during myelomonocytic differentiation of human leukemic cells.
    Cheng JC; Frackelton AR; Bearer EL; Kumar PS; Kannan B; Santos-Moore A; Rifai A; Settleman J; Clark JW
    Cell Growth Differ; 1995 Feb; 6(2):139-48. PubMed ID: 7756172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion.
    Zrihan-Licht S; Fu Y; Settleman J; Schinkmann K; Shaw L; Keydar I; Avraham S; Avraham H
    Oncogene; 2000 Mar; 19(10):1318-28. PubMed ID: 10713673
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of p190 on Tyr1105 by c-Src is necessary but not sufficient for EGF-induced actin disassembly in C3H10T1/2 fibroblasts.
    Haskell MD; Nickles AL; Agati JM; Su L; Dukes BD; Parsons SJ
    J Cell Sci; 2001 May; 114(Pt 9):1699-708. PubMed ID: 11309200
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.
    Fincham VJ; Chudleigh A; Frame MC
    J Cell Sci; 1999 Mar; 112 ( Pt 6)():947-56. PubMed ID: 10036244
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation.
    Hu KQ; Settleman J
    EMBO J; 1997 Feb; 16(3):473-83. PubMed ID: 9034330
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosine phosphorylation of Ras GTPase-activating protein stabilizes its association with p62 at membranes of v-Src transformed cells.
    Park S; Jove R
    J Biol Chem; 1993 Dec; 268(34):25728-34. PubMed ID: 7503985
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src.
    Neet K; Hunter T
    Mol Cell Biol; 1995 Sep; 15(9):4908-20. PubMed ID: 7544435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complex formation between the p21ras GTPase-activating protein and phosphoproteins p62 and p190 is independent of p21ras signalling.
    Pronk GJ; de Vries-Smits AM; Ellis C; Bos JL
    Oncogene; 1993 Oct; 8(10):2773-80. PubMed ID: 8378086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation.
    Brouns MR; Matheson SF; Settleman J
    Nat Cell Biol; 2001 Apr; 3(4):361-7. PubMed ID: 11283609
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activated Src tyrosine kinase phosphorylates Tyr-457 of bovine GTPase-activating protein (GAP) in vitro and the corresponding residue of rat GAP in vivo.
    Park S; Liu X; Pawson T; Jove R
    J Biol Chem; 1992 Aug; 267(24):17194-200. PubMed ID: 1512257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo.
    Ridley AJ; Self AJ; Kasmi F; Paterson HF; Hall A; Marshall CJ; Ellis C
    EMBO J; 1993 Dec; 12(13):5151-60. PubMed ID: 8262058
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of extracellular signal-regulated kinase activity by p120 RasGAP does not involve its pleckstrin homology or calcium-dependent lipid binding domains but does require these domains to regulate cell proliferation.
    Koehler JA; Moran MF
    Cell Growth Differ; 2001 Nov; 12(11):551-61. PubMed ID: 11714636
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formation of complexes involving RasGAP and p190 RhoGAP during morphogenetic events of the gastrulation in xenopus.
    Dupont H; Blancq M
    Eur J Biochem; 1999 Oct; 265(2):530-8. PubMed ID: 10504383
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The GTPase and Rho GAP domains of p190, a tumor suppressor protein that binds the M(r) 120,000 Ras GAP, independently function as anti-Ras tumor suppressors.
    Wang DZ; Nur-E-Kamal MS; Tikoo A; Montague W; Maruta H
    Cancer Res; 1997 Jun; 57(12):2478-84. PubMed ID: 9192829
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.